Results 71 to 80 of about 3,323 (218)

Working with clients engaging in recurrent suicidal behavior: impacts on community mental health practitioners

Frontiers in Public Health
BackgroundPractitioners have reported negative emotional impacts following client suicide. However, there is a paucity of literature exploring the impacts of working with clients engaging in suicidal behavior and on the impacts of repeat exposure to ...
Megan Collisson, Jacinta Hawgood
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Inflammation impairs post-hospital discharge growth among children hospitalised with acute illness in sub-Saharan Africa and south Asia

Nature Communications
In resource-limited settings, children often experience poor growth following illness, but the mechanisms are poorly understood. This cohort study in six countries in sub-Saharan Africa and south Asia investigates pathways linking inflammation and post ...
James M. Njunge, Evans O. Mudibo, Jasper Bogaert, Benedict Orindi, Charles J. Sande, Celine Bourdon, Caroline Tigoi, Moses M. Ngari, Narshion Ngao, Elisha Omer, Wilson Gumbi, Robert Musyimi, Molline Timbwa, Shalton Mwaringa, Agnes Gwela, Johnstone Thitiri, Ezekiel Mupere, Christina L. Lancioni, Gerard Bryan Gonzales, Benson O. Singa, Emmie Mbale, Wieger P. Voskuijl, Donna M. Denno, Abdoulaye Hama Diallo, Roseline Maϊmouna Bamouni, Mohammod Jobayer Chisti, Abu Sadat Mohammad Sayeem Bin Shahid, Tahmeed Ahmed, Ali Faisal Saleem, Syed Asad Ali, Holm H. Uhlig, Kirkby D. Tickell, Robert H. J. Bandsma, Judd L. Walson, James A. Berkley   +34 more
doaj   +1 more source

Exploring the impacts of colostrum on systemic immune development in dairy calves

Journal of Dairy Science
: Colostrum provides essential immune components, but its role in shaping neonatal immune development is not fully understood. Twenty-four Holstein calves were randomly assigned to 1 of 3 treatments: fresh colostrum (n = 8), frozen colostrum (n = 8), or ...
M. Cid de la Paz, F. Viquez-Umana, M. Mancheno, T. Fernandez-Wallace, H.C. Mantovani, L.R. Cangiano   +5 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Information impact on transportation systems

Journal of Computational Science, 2015
AbstractWith a broader distribution of personal smart devices and with an increasing availability of advanced navigation tools, more drivers can have access to real time information regarding the traffic situation. Our research focuses on determining how using the real time information about a transportation system could influence the system itself. We
Sorina Litescu, Vaisagh Viswanathan, Michael Lees, Alois C. Knoll, Heiko Aydt   +4 more
openaire   +3 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

The impact of fraud on reputation systems

Games and Economic Behavior
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Jan Philipp Krügel, Fabian Paetzel
openaire   +1 more source