Results 91 to 100 of about 3,045,517 (253)

PCIC corporate report 2019-2020 [PDF]

, 2020
The Pacific Climate Impacts Constortium (PCIC) corporate report for 2019 ...
Pacific Climate Impacts Consortium (PCIC)
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Systemic Weather Risk and Crop Insurance: The Case of China [PDF]

The supply of affordable crop insurance is hampered by the existence of systemic weather risk which results in large risk premiums. In this article, we assess the systemic nature of weather risk for 17 agricultural production regions in China and explore
Wei Xu, Martin Odening, Ji Cao, Ostap Okhrin   +3 more
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Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

The threat of systemic risk in banking: evidence for Europe [PDF]

This paper attempts to answer the question whether the threat of systemic risk in banking exists only on a national or on a European level. Following De Nicolo and Kwast (2001), mean rolling-window correlations between bank stock returns are used as a ...
Schüler, Martin
core  

PCIC corporate report 2018-2019 [PDF]

, 2019
The Pacific Climate Impacts Constortium (PCIC) corporate report for 2018 ...
Pacific Climate Impacts Consortium (PCIC)
core  

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

The impacts of gender differences on systemic lupus erythematosus and lupus nephritis

Linchuang shenzangbing zazhi, 2019
Systemic lupus erythematosus is a common autoimmune disease,and lupus nephritis is one of its common complications. Their clinical manifestations have differences. The incidence ratio of male to female varies by age group.
LI Chun-hong, TIAN Jie
doaj  

Osteoimmunological impacts of micro/nanoplastics: systemic translocation, inflammatory responses, and bone remodeling disruption

Frontiers in Immunology
Ingested environmental micro- and nanoplastics (MNPs) may represent an emerging systemic health concern. Although toxicological research has mainly focused on the gastrointestinal tract, increasing evidence suggests that the highly vascularized bone ...
Jinzhu Fan, Jinmeng Li, Chao Hao, Yigeng Hui   +3 more
doaj   +1 more source