Results 131 to 140 of about 3,434,192 (362)

Sarcopenia correlates with systemic inflammation in COPD

, 2017
Min Kwang Byun,1 Eun Na Cho,1 Joon Chang,2 Chul Min Ahn,1 Hyung Jung Kim1 1Division of Pulmonology, Department of Internal Medicine, Gangnam Severance Hospital, 2Division of Pulmonology, Department of Internal Medicine, Severance Hospital, Yonsei ...
Ahn CM, Byun MK, Kim HJ, Chang J, Cho EN
core  

Tissue Destruction in Bullous Pemphigoid Can Be Complement Independent and May Be Mitigated by C5aR2

Frontiers in Immunology, 2018
Bullous pemphigoid (BP), the most frequent autoimmune bullous disorder, is a paradigmatic autoantibody-mediated disease associated with autoantibodies against BP180 (type XVII collagen, Col17).
Christian M. Karsten, Tina Beckmann, Maike M. Holtsche, Jenny Tillmann, Sabrina Tofern, Franziska S. Schulze, Eva Nina Heppe, Ralf J. Ludwig, Detlef Zillikens, Inke R. König, Jörg Köhl, Jörg Köhl, Enno Schmidt, Enno Schmidt   +13 more
doaj   +1 more source

BCG vaccination in humans inhibits systemic inflammation in a sex-dependent manner.

Journal of Clinical Investigation, 2020
BACKGROUND Induction of innate immune memory, also termed trained immunity, by the anti-tuberculosis vaccine Bacillus Calmette-Guérin (BCG) contributes to protection against heterologous infections.
V. Koeken, L. Bree, V. Mourits, S. Moorlag, J. Walk, B. Cirovic, R. Arts, M. Jaeger, H. Dijkstra, H. Lemmers, L. Joosten, C. Benn, R. Crevel, M. Netea, M. Netea   +14 more
semanticscholar   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Moderate glucose supply reduces hemolysis during systemic inflammation

, 2018
Johannes Jägers,1 Stephan Brauckmann,2 Michael Kirsch,1 Katharina Effenberger-Neidnicht1,3 1Institute of Physiological Chemistry, University Hospital Essen, Essen, Germany; 2Clinic for Anesthesiology and Intensive Care, University Hospital Essen ...
Effenberger-Neidnicht K, Kirsch M, Jägers J, Brauckmann S   +3 more
core  

Systemic Immune-Inflammation and Systemic Inflammation Response Indices are Predictive Markers of Mortality in Inpatients Internal Medicine Services

International Journal of General Medicine, 2023
Betül Çavuşoğlu Türker,1 Süleyman Ahbab,1 Fatih Türker,1 Emre Hoca,1 Ece Çiftçi Öztürk,1 Atay Can Kula,2 Hüseyin Öztürk,3 Ayşe Öznur Urvasızoğlu,1 Merve Bulut,4 Özge Yasun,5 Hayriye Esra Ataoğlu1 1Department of ...
Çavuşoğlu Türker B, Ahbab S, Türker F, Hoca E, Çiftçi Öztürk E, Kula AC, Öztürk H, Urvasızoğlu AÖ, Bulut M, Yasun Ö, Ataoğlu HE   +10 more
doaj  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Use of electronic health records to investigate the role of acute inflammation and infection in vascular disease [PDF]

Previous studies have demonstrated that acute systemic inflammation after surgery or infection is associated with a transient increase in the risk of vascular events. This suggests that vascular risk is not stable but fluctuates within short periods in
Minassian, C
core   +1 more source

Age-Associated Microbial Dysbiosis Promotes Intestinal Permeability, Systemic Inflammation, and Macrophage Dysfunction

Cell Host and Microbe, 2017
Summary Levels of inflammatory mediators in circulation are known to increase with age, but the underlying cause of this age-associated inflammation is debated.
Netusha Thevaranjan, Alicja Puchta, Christian Schulz, Avee Naidoo, J. Szamosi, C. Verschoor, Dessi Loukov, L. P. Schenck, J. Jury, K. Foley, J. Schertzer, M. Larché, D. Davidson, E. Verdú, M. Surette, D. Bowdish   +15 more
semanticscholar   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source