Results 191 to 200 of about 736,102 (303)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Effect and safety of sivelestat on acute severe pancreatitis with systemic inflammatory response syndrome: a retrospective study. [PDF]

Sci Rep
Xie J, Lei R, Pei H, Gu Y, Zhang L, Liu J, Huang Y, Zhang Y, Zi Y, Zhu C, Zhu Z.   +10 more
europepmc   +1 more source

RIP kinase-dependent necrosis drives lethal systemic inflammatory response syndrome.

Immunity, 2011
L. Duprez, N. Takahashi, F. Van Hauwermeiren, B. Vandendriessche, V. Goossens, T. Vanden Berghe, W. Declercq, C. Libert, A. Cauwels, P. Vandenabeele   +9 more
semanticscholar   +1 more source

Dual Covalent Targeting of STING Cysteines 292/309 Disrupts Functional Oligomerization and Enables Potent Antagonist Development

Advanced Science, EarlyView.
We report a rational design strategy for STING antagonists by dual covalent targeting of Cys292/309 in its C‐terminal domain, directly preventing functional oligomerization. Through covalent warhead repurposing, we identified P005091 and revealed its unique dual‐cysteine mechanism.
Yuxuan Zhao, Ling Huang, Wenjing Qin, Bin Zhang, Yang Yang, Xue Chen, Xiaoquan Wang, Weilin Zhou, Feiyang Chen, Zhenyu Li, Liyuan Le, Yiqiu Zhang, Zhen Xiang, Lu Zhang, Fei Wang, Dan Lei, Zi‐zhe Cai, Ying Gao, Yong Chen, Xuecen Wang, Junmin Quan, Shuixing Zhang, Xianzhang Bu, Xin Yue   +23 more
wiley   +1 more source

Association of Systemic Inflammatory Response Syndrome With Cardiovascular Events After Mitral Transcatheter Edge-to-Edge Repair. [PDF]

J Am Heart Assoc
Mannina C, Sharma A, Carbone A, Bossone E, Tuttolomondo A, Argulian E, Neibart E, Hadley MB, Halperin J, Dangas G, Sharma SK, Kini A, Lerakis S.   +12 more
europepmc   +1 more source

NEUTROPHILS AND SYSTEMIC INFLAMMATORY RESPONSE SYNDROME

Wounds and wound infections. The prof. B.M. Kostyuchenok journal, 2015
A. A. Galkin, V. S. Demidova
openaire   +2 more sources

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

Stored RBC transfusions leads to the systemic inflammatory response syndrome in anemic murine neonates. [PDF]

Inflamm Res
Ramatchandirin B, Balamurugan MA, Desiraju S, Chung Y, Wojczyk BS, MohanKumar K.   +5 more
europepmc   +1 more source

Innovative Metasurface Colorimetric Cell‐on‐a‐Chip Sensor for Continuous, Label‐Free, Non‐Destructive Assessment of Intestinal Barrier Dynamics

Advanced Science, EarlyView.
We developed a real‐time, label‐free, high‐throughput cell‐on‐a‐chip system based on a metasurface plasmon resonance colorimetric sensor (MetaSPRCS) to evaluate intestinal barrier function. This platform enables continuous monitoring of cell adhesion, proliferation, and barrier layer formation, disruption, and repair.
Youqian Chen, Wen Li, Jiaying Feng, Yue Shu, Yihui Yang, Yuyan Wang, Rui Li, Hanlin Zhou, Xinfan Yang, Yuxue Guo, Mingqian Chen, Wenjun Hu, Gang Logan Liu, Liping Huang, Yanan Li   +14 more
wiley   +1 more source

Exploring Core Genes Associated with Sepsis and Systemic Inflammatory Response Syndrome Using Single-Cell Sequencing Technology. [PDF]

J Inflamm Res
Shen Y, Leng L, Hu Y.
europepmc   +1 more source