Abstract Monitoring subpopulations of CD4+ T cells in blood, especially regulatory CD4+CD25+Foxp3+CD127loT cells, has the potential to identify tolerance to transplants and defects that cause autoimmunity. CD45RA is expressed by naïve/resting CD4+, not by activated cells.
Nirupama D. Verma+7 more
wiley +1 more source
Phenome-wide causal proteomics enhance systemic lupus erythematosus flare prediction: A study in Asian populations [PDF]
Objective: Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by unpredictable flares. This study aimed to develop a novel proteomics-based risk prediction model specifically for Asian SLE populations to enhance personalized disease management and early intervention.
arxiv
Epidemiology of common allergic diseases in China: Current position and implications
Abstract The prevalence of common allergic diseases, including allergic rhinitis, asthma, atopic dermatitis, and food allergy, has increased dramatically with rising industrialization in China, leading to a significant socio‐economic burden.
Xu Xu+4 more
wiley +1 more source
LP-126 The infectious complication in multitarget therapy of class V lupus nephritis: a case report
Anastasiia Shumilova+3 more
doaj +1 more source
A data-driven approach to discover and quantify systemic lupus erythematosus etiological heterogeneity from electronic health records [PDF]
Systemic lupus erythematosus (SLE) is a complex heterogeneous disease with many manifestational facets. We propose a data-driven approach to discover probabilistic independent sources from multimodal imperfect EHR data. These sources represent exogenous variables in the data generation process causal graph that estimate latent root causes of the ...
arxiv
Abstract Aims Inflammation plays a critical role in both the development and progression of heart failure (HF), which is a leading cause of morbidity and mortality worldwide. However, the causality between specific inflammation‐related proteins and HF risk remains unclear.
Xian‐Guan Zhu+9 more
wiley +1 more source
LP-048 Characteristics and clinical outcome of incomplete systemic lupus erythematosus
Anastasiia Shumilova+6 more
doaj +1 more source
The Relation of Immunoglobulin Class, Pattern of Antinuclear Antibody, and Complement-Fixing Antibodies to DNA in Sera from Patients with Systemic Lupus Erythematosus* [PDF]
Naomi F. Rothfield, B. David Stollar
openalex +1 more source
Estimating treatment effects with competing intercurrent events in randomized controlled trials [PDF]
The analysis of randomized controlled trials is often complicated by intercurrent events (ICEs) -- events that occur after treatment initiation and affect either the interpretation or existence of outcome measurements. Examples include treatment discontinuation or the use of additional medications.
arxiv