Results 11 to 20 of about 872,427 (309)

Stratification of Systemic Lupus Erythematosus Patients Using Gene Expression Data to Reveal Expression of Distinct Immune Pathways [PDF]

open access: yes, 2020
Systemic lupus erythematosus (SLE) is the tenth leading cause of death in females 15-24 years old in the US. The diversity of symptoms and immune pathways expressed in SLE patients causes difficulties in treating SLE as well as in new clinical trials.
arxiv   +1 more source

Systemic Lupus Erythematosus [PDF]

open access: yesBMJ, 1957
Lupus is a serious, potentially life-threatening disease. Its natural history is to culminate in a crescendo of autoimmunity and organ involvement. Difficulty arriving at the diagnosis may delay institution of therapy, which although helpful brings new problems. The fundamental understanding of this disease has made major strides. There is no consensus
openaire   +6 more sources

Risk of herpes zoster in patients with systemic lupus erythematosus: a three-year follow-up study using a nationwide population-based cohort

open access: yesClinics, 2011
OBJECTIVE: The goal of the present study was to estimate the risk ratio of herpes zoster among systemic lupus erythematosus patients after disease onset compared with a cohort of patients without systemic lupus erythematosus over a three-year period ...
Hsin-Hua Chen   +5 more
doaj   +1 more source

Determinant Factors of Morbidity in Patients with Systemic Lupus Erythematosus

open access: yesActa Médica Portuguesa, 2017
Introduction: Severity in systemic lupus erythematosus may vary from mild to even fatal consequences. There are no biomarkers to predict the disease’s prognosis.
Margarida Jacinto   +3 more
doaj   +1 more source

Lupus erythematosus: considerations about clinical, cutaneous and therapeutic aspects [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2014
Systemic Lupus Erythematosus is a chronic inflammatory disease with multifactorial etiology. Although clinical manifestations are varied, the skin is an important target-organ, which contributes to the inclusion of skin lesions in 4 out of the 17 new ...
Jucelio Pereira Moura Filho   +6 more
doaj   +1 more source

Natural language processing to identify lupus nephritis phenotype in electronic health records [PDF]

open access: yesarXiv, 2021
Systemic lupus erythematosus (SLE) is a rare autoimmune disorder characterized by an unpredictable course of flares and remission with diverse manifestations. Lupus nephritis, one of the major disease manifestations of SLE for organ damage and mortality, is a key component of lupus classification criteria.
arxiv  

Classification of histopathology images using ConvNets to detect Lupus Nephritis [PDF]

open access: yesarXiv, 2021
Systemic lupus erythematosus (SLE) is an autoimmune disease in which the immune system of the patient starts attacking healthy tissues of the body. Lupus Nephritis (LN) refers to the inflammation of kidney tissues resulting in renal failure due to these attacks.
arxiv  

The significance of M1/M2 macrophage-like monocytes in children with systemic lupus erythematosus

open access: yesEuropean Journal of Inflammation, 2019
Monocytes/macrophages are important in the development of systemic lupus erythematosus. To research M1 and M2 macrophage-like monocytes in the peripheral blood of children with systemic lupus erythematosus and explore the clinical significance, M1 and M2
Xiao-Ling Niu   +6 more
doaj   +1 more source

Systemic Lupus Erythematosus

open access: yesDeckerMed Family Medicine, 2019
Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune illness characterized by autoantibodies directed at nuclear antigens that cause clinical and laboratory abnormalities, such as rash, arthritis, leukopenia and thrombocytopenia, alopecia, fever, nephritis, and neurologic disease.
Kyriakos A. Kirou, Michael D. Lockshin
openaire   +1 more source

Serum interleukin-17 levels are associated with nephritis in childhood-onset systemic lupus erythematosus

open access: yesClinics, 2015
OBJECTIVES: To determine the serum interleukin-17 (IL-17) levels in childhood-onset systemic lupus erythematosus patients and to evaluate the association between IL-17 and clinical manifestations, disease activity, laboratory findings and treatment ...
Karina de Oliveira Peliçari   +7 more
doaj   +1 more source

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