Results 221 to 230 of about 197,714 (301)

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Polymorphism of HLA class II alleles and tumor necrosis factor alpha promoter alleles in Hungarian patients with systemic lupus erythematosus and with primary Sjögren's syndrome [PDF]

, 2006
Kovács Attila
core  

Diversity in clinical Trials: The example of systemic lupus erythematosus. [PDF]

Contemp Clin Trials Commun
Bevan A, Carroll N, Wallstrom G, Sridharan S.   +3 more
europepmc   +1 more source

Metrnβ drives sepsis immunosuppression via macrophage reprogramming: A novel prognostic biomarker and therapeutic target

Interdisciplinary Medicine, EarlyView.
Metrnβ serves as a novel prognostic biomarker for sepsis and that targeted blockade of the Metrnβ‐c‐Kit axis represents a promising therapeutic strategy for sepsis. Abstract Sepsis is a heterogeneous syndrome critically driven by immunosuppression, yet lacking personalized prognostic markers and therapeutic targets. Here, we provide evidence to support
Xiao Li, Ai Chen, Chen Zhang, Meihong Da, Yonghui Liu, Zhi He, Chenyan Yuan, Shuo Ma, Yuming Yao, Dawen Chen, Meiling Zhou, Zhixin Song, Wenjing Lu, Chun‐Kwok Wong, Guoqiu Wu, Xun Gao   +15 more
wiley   +1 more source

Potential Roles of Prostaglandins PGD2, PGJ2, and PGE2 in the Pathogenesis of Systemic Lupus Erythematosus. [PDF]

Int J Mol Sci
Xu T, Luo XM.
europepmc   +1 more source

Preliminary Evaluation of a Novel Lupus Anticoagulant Activity Assay Unaffected by Anticoagulants

Journal of Clinical Laboratory Analysis, EarlyView.
A novel one‐step lupus anticoagulant (LA) assay based on the LA‐sensitivity ratio (LA‐SR) was developed to simplify diagnostic testing and reduce potential interference from anticoagulants. The LA‐SR method showed good agreement with guideline‐based LA testing (dRVVT and/or LA‐sensitive APTT) for the detection of LA and demonstrated limited influence ...
Ayu Hidaka, Risa Kaneshige, Seika Nakamura, Yukari Motoki, Junzo Nojima   +4 more
wiley   +1 more source

Validity and applicability of machine learning models for systemic lupus erythematosus diagnosis. [PDF]

Lupus Sci Med
Li RC, Huang AF, Su LC, Wang DC, Xu WD.
europepmc   +1 more source

Shared genetic and molecular architecture between neurodevelopmental disorders and type 1 diabetes

Journal of Intelligent Medicine, EarlyView.
Abstract Epidemiological and clinical studies have suggested possible associations between type 1 diabetes (T1D) and neurodevelopmental disorders (NDDs), but these relationships remain inconsistent across disorders and populations. To clarify whether such mixed findings, we investigated the genetic architecture linking T1D with autism spectrum disorder
Jingxuan Zhang, Zhentao Zhou, Lirong Zhu, Wei Liu   +3 more
wiley   +1 more source

TLR7 and TLR9 have overlapping but distinct roles in systemic lupus erythematosus and Sjögren's disease. [PDF]

Front Immunol
Biswas S, Kramer JM.
europepmc   +1 more source

Impact of pre‐surgical anxiety and fear on patient satisfaction following periodontal and implant surgical procedures

Journal of Periodontology, EarlyView.
Abstract Background Pre‐surgical anxiety (PSA) and pre‐surgical fear (PSF) may hinder patient compliance, while patient satisfaction (PS) is vital for adherence to treatment recommendations. This prospective study investigated the impact of PSA and PSF, and the influence of patient demographics and postoperative pain, on PS after periodontal and ...
Anum Haider, Dimitris N. Tatakis, Manuel Lagravere, Hollis Lai, Monica P. Gibson   +4 more
wiley   +1 more source