Results 21 to 30 of about 857,167 (170)

Lupus erythematosus: considerations about clinical, cutaneous and therapeutic aspects [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2014
Systemic Lupus Erythematosus is a chronic inflammatory disease with multifactorial etiology. Although clinical manifestations are varied, the skin is an important target-organ, which contributes to the inclusion of skin lesions in 4 out of the 17 new ...
Jucelio Pereira Moura Filho   +6 more
doaj   +1 more source

Antineutrophil Cytoplasmic Autoantibody-Negative Pauci-Immune Crescentic Glomerulonephritis in a Patient with Systemic Lupus Erythematosus

open access: yesCase Reports in Nephrology and Dialysis, 2022
Renal involvement in systemic lupus erythematosus is usually exhibited as lupus nephritis, which is a form of immune complex-mediated glomerulonephritis and one of the most severe organ manifestations of systemic lupus erythematosus.
Chee Eng Chan   +3 more
doaj   +1 more source

A Systematic Review of the Progression of Cutaneous Lupus to Systemic Lupus Erythematosus

open access: yesFrontiers in Immunology, 2022
Lupus erythematosus is an autoimmune disease that may manifest in a variety of organs and tissues including the skin, kidney, brain, heart and lung. Many patients present with cutaneous lupus, where disease is often limited to the skin, but are at risk ...
Paul Curtiss   +2 more
doaj   +1 more source

Migraine In Systemic Lupus Erythematosus in Rheumatological outpatients unit

open access: yesمجله كليه طب الكندي, 2019
Background: Migraine is common in systemic lupus erythematosus.It is a significant source of patient disability. Objective: To determine the rate of migraine in patients with systemic lupus erythematosus, to assess migraine type, severity, and the ...
Ameer Shaker
doaj   +1 more source

GPA-Tree: Statistical Approach for Functional-Annotation-Tree-Guided Prioritization of GWAS Results [PDF]

open access: yesarXiv, 2021
Motivation: In spite of great success of genome-wide association studies (GWAS), multiple challenges still remain. First, complex traits are often associated with many single nucleotide polymorphisms (SNPs), each with small or moderate effect sizes. Second, our understanding of the functional mechanisms through which genetic variants are associated ...
arxiv  

Clustering methods and Bayesian inference for the analysis of the evolution of immune disorders [PDF]

open access: yesarXiv, 2020
Choosing appropriate hyperparameters for unsupervised clustering algorithms in an optimal way depending on the problem under study is a long standing challenge, which we tackle while adapting clustering algorithms for immune disorder diagnoses. We compare the potential ability of unsupervised clustering algorithms to detect disease flares and remission
arxiv  

High Expression of CDK1 and NDC80 Predicts Poor Prognosis of Bladder Cancer [PDF]

open access: yesarXiv, 2021
Background: Bladder cancer is the 10th most common cancer worldwide, and its prevalence is increasing, especially in developing countries. Objective: In the present study, we employed gene expression profiles from the GSE163209 data set in the GEO database to identify potential molecular and genetic markers in BC patients.
arxiv  

Pincer nails: an initial and isolated cutaneous manifestation of systemic lupus erythematosus

open access: yesPrzegląd Dermatologiczny, 2017
Introduction . Pincer nail deformity due to systemic lupus erythematosus is a rare phenomenon and only three cases have been reported to date. Objective . To present a case of pincer nails in a systemic lupus erythematosus patient and a brief review of
Manoj Karbhari Pawar
doaj   +1 more source

Depressed serum IgM levels in SLE are restricted to defined subgroups [PDF]

open access: yes, 2017
Natural IgM autoantibodies have been proposed to convey protection from autoimmune pathogenesis. Herein, we investigated the IgM responses in 396 systemic lupus erythematosus (SLE) patients, divided into subgroups based on distinct autoantibody profiles. Depressed IgM levels were more common in SLE than in matched population controls.
arxiv   +1 more source

Psychiatric manifestations of systemic lupus erythematosus: A brief review with two case-reports

open access: yesSAGE Open Medical Case Reports
Neuropsychiatric systemic lupus erythematosus is a severe neurological and psychiatric manifestation following systemic lupus erythematosus. Neuropsychiatric systemic lupus erythematosus is a global concern with limited data on its impact on quality of ...
Faiz Mohammed Kassim   +4 more
doaj   +1 more source

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