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Nature Reviews Disease Primers, 2016
Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect many organs, including the skin, joints, the central nervous system and the kidneys. Women of childbearing age and certain racial groups are typically predisposed to developing the condition. Rare, inherited, single-gene complement deficiencies are strongly associated with SLE,
Arvind Kaul +2 more
exaly +11 more sources
Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect many organs, including the skin, joints, the central nervous system and the kidneys. Women of childbearing age and certain racial groups are typically predisposed to developing the condition. Rare, inherited, single-gene complement deficiencies are strongly associated with SLE,
Arvind Kaul +2 more
exaly +11 more sources
Pediatric Clinics of North America, 2005
Systemic lupus erythematosus (SLE) in children and adolescents is a multisystem autoimmune disease with a great variability in disease presentation and course. The diagnosis of SLE is based on the clinical and laboratory features consistent with this illness in the absence of other autoimmune disease that could explain the findings.
Earl D. Silverman, Susanne M. Benseler
openaire +4 more sources
Systemic lupus erythematosus (SLE) in children and adolescents is a multisystem autoimmune disease with a great variability in disease presentation and course. The diagnosis of SLE is based on the clinical and laboratory features consistent with this illness in the absence of other autoimmune disease that could explain the findings.
Earl D. Silverman, Susanne M. Benseler
openaire +4 more sources
New England Journal of Medicine, 2008
In their review article, Rahman and Isenberg (Feb. 28 issue)1 emphasize the role of anti–double-stranded DNA antibodies in the pathogenesis of systemic lupus erythematosus. Such antibodies also occur, however, in 23 to 64% of patients with type 1 autoimmune hepatitis, depending on the assay used.2 Interestingly, 36% of patients with type 1 autoimmune ...
Cynthia Aranow +2 more
openaire +4 more sources
In their review article, Rahman and Isenberg (Feb. 28 issue)1 emphasize the role of anti–double-stranded DNA antibodies in the pathogenesis of systemic lupus erythematosus. Such antibodies also occur, however, in 23 to 64% of patients with type 1 autoimmune hepatitis, depending on the assay used.2 Interestingly, 36% of patients with type 1 autoimmune ...
Cynthia Aranow +2 more
openaire +4 more sources
Systemic Lupus Erythematosus [PDF]
Journal of the American Academy of Nurse Practitioners, 1992 The reported change in the incidence of systemic lupus erythematosus (SLE) is mainly due to a greater awareness of the disease, and to the introduction of serological detection methods such as the LE cell assay and subsequently a variety of other antinuclear antibody assays.
Ruud J.T. Smeenk +2 more
openaire +5 more sources
Medical Clinics of North America, 1986
Systemic lupus erythematosus is a multisystem inflammatory disease characterized by autoantibody production. Recent investigations are providing insights into the immunoregulatory disturbances underlying this disease, and are clarifying the approach to diagnosis and treatment.
openaire +5 more sources
Systemic lupus erythematosus is a multisystem inflammatory disease characterized by autoantibody production. Recent investigations are providing insights into the immunoregulatory disturbances underlying this disease, and are clarifying the approach to diagnosis and treatment.
openaire +5 more sources
Drugs of Today, 2002
Systemic lupus erythematosus is a pleomorphic, autoimmune disorder of unknown cause that can afflict all parts of the body. New insights into its pathogenesis, the employment of preventive measures and combinations of immunosuppressive therapy, as well as the introduction of biologics, are beginning to alter the prognosis and improve the quality of ...
openaire +4 more sources
Systemic lupus erythematosus is a pleomorphic, autoimmune disorder of unknown cause that can afflict all parts of the body. New insights into its pathogenesis, the employment of preventive measures and combinations of immunosuppressive therapy, as well as the introduction of biologics, are beginning to alter the prognosis and improve the quality of ...
openaire +4 more sources
The Journal of the American Dental Association, 1980
A case of osteomyelitis of the mandible in a patient with systemic lupus erythematosus is described. Both the disease process and the treatment modalities must be understood for correct management.
Steven J. Samuelson +2 more
openaire +6 more sources
A case of osteomyelitis of the mandible in a patient with systemic lupus erythematosus is described. Both the disease process and the treatment modalities must be understood for correct management.
Steven J. Samuelson +2 more
openaire +6 more sources