Results 31 to 40 of about 456,719 (283)

Complement Activation in Patients With Probable Systemic Lupus Erythematosus and Ability to Predict Progression to American College of Rheumatology-Classified Systemic Lupus Erythematosus. [PDF]

, 2020
ObjectiveTo evaluate the frequency of cell-bound complement activation products (CB-CAPs) as a marker of complement activation in patients with suspected systemic lupus erythematosus (SLE) and the usefulness of this biomarker as a predictor of the ...
Alexander, Roberta Vezza, Arriens, Cristina, Collins, Christopher E, Dervieux, Thierry, Kalunian, Kenneth C, Massarotti, Elena M, Narain, Sonali, O'Malley, Tyler, Putterman, Chaim, Ramsey-Goldman, Rosalind, Saxena, Amit, Wallace, Daniel J, Weinstein, Arthur   +12 more
core   +2 more sources

Belimumab : a technological advance for systemic lupus erythematosus patients? Report of a systematic review and meta-analysis [PDF]

, 2013
Objectives: To undertake a systematic review and meta-analysis to investigate clinical effectiveness of belimumab for patients with systemic lupus erythematosus (SLE) and antinuclear and/or anti-double-stranded DNA (dsDNA) autoantibodies.
Clarke, Aileen, Connock, M., Court, Rachel A., Cummins, E., Gordon, Caroline, Grove, Amy L., Hartley, Louise, Kandala, Ngianga-Bakwin, Mohiuddin, Syed, Sutcliffe, P. (Paul)   +9 more
core   +1 more source

Trial of Anifrolumab in Active Systemic Lupus Erythematosus.

New England Journal of Medicine, 2019
BACKGROUND Anifrolumab, a human monoclonal antibody to type I interferon receptor subunit 1 investigated for the treatment of systemic lupus erythematosus (SLE), did not have a significant effect on the primary end point in a previous phase 3 trial.
E. Morand, R. Furie, Yoshiya Tanaka, I. Bruce, A. Askanase, C. Richez, S. Bae, P. Brohawn, L. Pineda, A. Berglind, R. Tummala   +10 more
semanticscholar   +1 more source

Systemic lupus erythematosus [PDF]

Postgraduate Medical Journal, 1988
Summary Systemic lupus erythematosus is a common disease--studies throughout the world broadly agree on a prevalence of 1 in 1000 women. Recently an important clinical advance has come from the description of a syndrome of recurrent thrombosis, recurrent abortion and neurological disease associated with antiphospholipid antibodies.
openaire   +3 more sources

The development and initial validation of the Systemic Lupus International Collaborating Clinics/American College of Rheumatology damage index for systemic lupus erythematosus.

Arthritis & Rheumatism, 1996
OBJECTIVE To develop and perform an initial validation of a damage index for systemic lupus erythematosus (SLE). METHODS A list of items considered to reflect damage in SLE was generated through a nominal group process. A consensus as to which items to
D. Gladman, E. Ginzler, C. Goldsmith, P. Fortin, Matthew H. Liang, J. Sánchez-Guerrero, M. Urowitz, P. Bacon, S. Bombardieri, J. Hanly, John Jones, E. Hay, D. Symmons, D. Isenberg, Kenneth Kalunion, P. Maddison, O. Nived, G. Sturfelt, M. Petri, Martin Richter, M. Snaith, A. Zoma   +21 more
semanticscholar   +1 more source

Mapping Systemic Lupus Erythematosus heterogeneity at the single-cell level

Nature Immunology, 2020
Patients with systemic lupus erythematosus (SLE) display a complex blood transcriptome whose cellular origin is poorly resolved. Using single-cell RNA sequencing, we profiled ~276,000 peripheral blood mononuclear cells from 33 children with SLE with ...
Djamel Nehar-Belaid, Seunghee Hong, R. Marches, Guo Chen, M. Bolisetty, Jeanine Baisch, Lynnette Walters, M. Punaro, R. Rossi, C. Chung, Richie Huynh, Prashant Singh, W. Flynn, Joy-Ann Tabanor-Gayle, N. Kuchipudi, A. Mejías, Magalie A. Collet, Anna Lisa Lucido, K. Palucka, P. Robson, S. Lakshminarayanan, O. Ramilo, Tracey Wright, V. Pascual, J. Banchereau   +24 more
semanticscholar   +1 more source

Determinant Factors of Morbidity in Patients with Systemic Lupus Erythematosus

Acta Médica Portuguesa, 2017
Introduction: Severity in systemic lupus erythematosus may vary from mild to even fatal consequences. There are no biomarkers to predict the disease’s prognosis.
Margarida Jacinto, Eliana Silva, Nuno Riso, Maria Francisca Moraes-Fontes   +3 more
doaj   +1 more source

Review of presentations at the 6th European Lupus Meeting 3-5 March 2005. [PDF]

, 2005
The 6th European Lupus Meeting was held at the Royal College of Physicians of London and was attended by 450 delegates. The conference brought together leading speakers from Europe and North America who reviewed current knowledge and exciting new ...
Bowman, SJ, Giles, IP, Ioannou, Y, Rahman, A   +3 more
core   +1 more source

Systemic lupus erythematosus [PDF]

BMJ, 2007
Systemic lupus erythematosus in pregnancy brings risks for the mother, and possible harm to the fetus if the disease is treated.
Lucy H, Mackillop, Sarah J, Germain, Catherine, Nelson-Piercy   +2 more
openaire   +2 more sources

Skin involvement in systemic lupus erythematosus: a review article [PDF]

Romanian Journal of Rheumatology, 2023
Cutaneous disease is one of the most frequent manifestations of systemic lupus erythematosus (SLE), being classified as LE-specific and LE-nonspecific.
Teodora Baciu, Stefan Neculai Nica, Sanziana Daia-Iliescu, Andreea Borangiu, Claudia Cobilinski, Daniela Opris-Belinski, Ruxandra Ionescu, Ioana Cristina Saulescu   +7 more
doaj   +1 more source