Львівський клінічний вісник, 2017 Introduction. Systemic lupus erythematosus is one of the autoimmune diseases prevailing in women of reproductive age and is, quite often, the cause of their disability. In recent years, the attention of researchers has been focused on clarifying the role
Abrahamovych U. +2 more
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multi-GPA-Tree: Statistical Approach for Pleiotropy Informed and Functional Annotation Tree Guided Prioritization of GWAS Results [PDF]
arXiv, 2023 Genome-wide association studies (GWAS) have successfully identified over two hundred thousand genotype-trait associations. Yet some challenges remain. First, complex traits are often associated with many single nucleotide polymorphisms (SNPs), most with small or moderate effect sizes, making them difficult to detect. Second, many complex traits share a
arxiv
MIRACLE: Multi-task Learning based Interpretable Regulation of Autoimmune Diseases through Common Latent Epigenetics [PDF]
arXiv, 2023 DNA methylation is a crucial regulator of gene transcription and has been linked to various diseases, including autoimmune diseases and cancers. However, diagnostics based on DNA methylation face challenges due to large feature sets and small sample sizes, resulting in overfitting and suboptimal performance. To address these issues, we propose MIRACLE,
arxiv
Audiovestibular Dysfunction in Systemic Lupus Erythematosus Patients: A Systematic Review
DiagnosticsAudiovestibular dysfunction in patients with systemic lupus erythematosus has been underestimated for decades. Systemic lupus erythematosus can affect both the auditory and vestibular systems simultaneously.
Jiann-Jy Chen +5 more
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A new stochastic differential equation modelling incidence and prevalence with an application to systemic lupus erythematosus in England and Wales, 1995 [PDF]
arXiv, 2012 This article reformulates a common illness-death model in terms of a new system of stochastical differential equations (SDEs). The SDEs are used to estimate epidemiological characteristics and burden of systemic lupus erythematosus in England and Wales in 1995.
arxiv
Systemic lupus erythematosus in African-American women: Cognitive physiological modules, autoimmune disease, and structured psychosocial stress [PDF]
arXiv, 2003 Examining elevated rates of systemic lupus erythematosus in African-American women from perspectives of immune cognition suggests the disease constitutes an internalized physiological image of external structured psychosocial stress, a 'pathogenic social hierarchy' involving the synergism of racism and gender discrimination in the context of policy ...
arxiv
Alcohol, smoking and illicit drug use in pediatric systemic lupus erythematosus patients
Revista Brasileira de Reumatologia, 2016 Objective To evaluate alcohol, smoking and/or illicit drug use, and history of bullying in adolescent childhood-onset systemic lupus erythematosus and healthy controls. Methods 174 adolescents with pediatric rheumatic diseases were selected.
Marlon van Weelden +5 more
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European Journal of Case Reports in Internal Medicine, 2020 Manifestations of chronic cutaneous lupus erythematosus are variable. Periorbital and facial swelling occurs in dermatomyositis and systemic lupus, but it has been rarely reported as a manifestation of exclusively cutaneous lupus.
Mónica García-Arpa +4 more
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SAGE Open Medicine, 2018 Objective: Infections are a major cause of morbidity and mortality in systemic lupus erythematosus. Clinical outcomes of systemic lupus erythematosus patients hospitalized due to infections vary among different ethnic populations. Thus, we determined the
Patricia Jordán-González +3 more
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Systemic lupus erythematosus with subacute cutaneous manifestation – acute on chronic.
Galicia Clínica, 2018 Systemic Lupus Erythematosus (SLE) presents as a continuum, with some patients demonstrating only cutaneous manifestations, such as Chronic Cutaneous Lupus Erythematosus (CCLE) or other more severe organ manifestations as in SLE.
Juliana Lopes, Isabel Almeida
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