COMO: A Pipeline for Multi-Omics Data Integration in Metabolic Modeling and Drug Discovery [PDF]
arXiv, 2020 Identifying potential drug targets using metabolic modeling requires integrating multiple modeling methods and heterogenous biological datasets, which can be challenging without sophisticated tools. We developed COMO, a user-friendly pipeline that integrates multi-omics data processing, context-specific metabolic model development, simulations, drug ...
arxiv
The Spitzer c2d Survey of Large, Nearby, Interstellar Clouds. XI. Lupus Observed With IRAC and MIPS [PDF]
, 2008 We present c2d Spitzer/IRAC observations of the Lupus I, III and IV dark clouds and discuss them in combination with optical and near-infrared and c2d MIPS data. With the Spitzer data, the new sample contains 159 stars, 4 times larger than the previous one.
arxiv +1 more source
The Lupus Transit Survey For Hot Jupiters: Results and Lessons [PDF]
, 2009 We present the results of a deep, wide-field transit survey targeting Hot Jupiter planets in the Lupus region of the Galactic plane conducted over 53 nights concentrated in two epochs separated by a year. Using the Australian National University 40-inch telescope at Siding Spring Observatory (SSO), the survey covered a 0.66 sq. deg. region close to the
arxiv +1 more source
A case of Lemierre syndrome combined with a suspected systemic lupus erythematosus flare
SAGE Open Medical Case Reports, 2019 Lemierre syndrome develops in healthy young patients as a result of bacteremia after oral cavity infection. It causes thrombophlebitis in the internal jugular vein.
Teruhiro Fujii +4 more
doaj +1 more source
Lupus cardiomyopathy in young woman with high lupus activity [PDF]
Българска кардиологияSystemic lupus erythematosus is a chronic autoimmune disorder affecting predominantly young women. Cardiac involvement in systemic lupus erythematosus is common and the typical manifestations are pericarditis, myocarditis, valvular disease, coronary ...
A. Borizanova-Petkova +5 more
doaj +3 more sources
Integrated machine learning pipeline for aberrant biomarker enrichment (i-mAB): characterizing clusters of differentiation within a compendium of systemic lupus erythematosus patients [PDF]
arXiv, 2018 Clusters of differentiation (CD) are cell surface biomarkers that denote key biological differences between cell types and disease state. CD-targeting therapeutic monoclonal antibodies (mAB) afford rich trans-disease repositioning opportunities. Within a compendium of systemic lupus erythematous (SLE) patients, we applied the Integrated machine ...
arxiv
Lupus-TR-3b: A Low-Mass Transiting Hot Jupiter in the Galactic Plane? [PDF]
, 2007 We present a strong case for a transiting Hot Jupiter planet identified during a single-field transit survey towards the Lupus Galactic plane. The object, Lupus-TR-3b, transits a V=17.4 K1V host star every 3.91405d. Spectroscopy and stellar colors indicate a host star with effective temperature 5000 +/- 150K, with a stellar mass and radius of 0.87 ...
arxiv +1 more source
Visual Analytics of Group Differences in Tensor Fields: Application to Clinical DTI [PDF]
arXiv, 2017 We present a visual analytics system for exploring group differences in tensor fields with respect to all six degrees of freedom that are inherent in symmetric second-order tensors. Our framework closely integrates quantitative analysis, based on multivariate hypothesis testing and spatial cluster enhancement, with suitable visualization tools that ...
arxiv
Journal of Translational Autoimmunity, 2020 Neuropsychiatric systemic lupus erythematosus is an autoimmune disorder characterized by an irregular exchange between the central nervous system and the immune system, leading to the outbreak of neurological conditions with possible disabling effects ...
Sangita Khatri +7 more
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