Results 51 to 60 of about 872,427 (309)

Systemic lupus erythematosus in African-American women: Cognitive physiological modules, autoimmune disease, and structured psychosocial stress [PDF]

open access: yesarXiv, 2003
Examining elevated rates of systemic lupus erythematosus in African-American women from perspectives of immune cognition suggests the disease constitutes an internalized physiological image of external structured psychosocial stress, a 'pathogenic social hierarchy' involving the synergism of racism and gender discrimination in the context of policy ...
arxiv  

Mixed Autoimmune Hemolytic Anemia: A Systematic Review of Epidemiology, Clinical Characteristics, Therapies, and Outcomes

open access: yesAmerican Journal of Hematology, EarlyView.
Mixed autoimmune hemolytic anemia (AIHA) is a rare condition characterized by the presence of both warm and cold autoantibodies, often leading to severe, treatment‐resistant hemolysis. In this systematic review of 81 patients across 35 studies, the median age was 45 years with a notable female predominance.
Jeremy W. Jacobs   +12 more
wiley   +1 more source

Audiovestibular Dysfunction in Systemic Lupus Erythematosus Patients: A Systematic Review

open access: yesDiagnostics
Audiovestibular dysfunction in patients with systemic lupus erythematosus has been underestimated for decades. Systemic lupus erythematosus can affect both the auditory and vestibular systems simultaneously.
Jiann-Jy Chen   +5 more
doaj   +1 more source

A Transcriptome‐Wide Mendelian Randomization Study in Isolated Human Immune Cells Highlights Risk Genes Involved in Viral Infections and Potential Drug Repurposing Opportunities for Schizophrenia

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Schizophrenia is a neurodevelopmental psychiatric disorder characterized by symptoms of psychosis, thought disorder, and flattened affect. Immune mechanisms are associated with schizophrenia, though the precise nature of this relationship (causal, correlated, consequential) and the mechanisms involved are not fully understood.
David Stacey   +6 more
wiley   +1 more source

Persistent Facial Oedema and Erythema in a Woman, An Uncommon Manifestation of Chronic Cutaneous Lupus Erythematosus

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2020
Manifestations of chronic cutaneous lupus erythematosus are variable. Periorbital and facial swelling occurs in dermatomyositis and systemic lupus, but it has been rarely reported as a manifestation of exclusively cutaneous lupus.
Mónica García-Arpa   +4 more
doaj   +1 more source

Systemic lupus erythematosus [PDF]

open access: yesClinical Medicine, 2017
Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune disease that is highly heterogeneous in its presentation. This can pose significant challenges for physicians responsible for the diagnosis and treatment of such patients. SLE arises from a combination of genetic, epigenetic and environmental factors.
Natasha Jordan   +2 more
openaire   +3 more sources

Psychoses of Epilepsy: Unravelling the Phenotypic and Genotypic Features

open access: yesAnnals of Neurology, EarlyView.
Objectives We analyzed the genotypic and phenotypic features of patients with psychosis of epilepsy (POE). Methods Patients with POE recruited to an epilepsy genetics research program underwent phenotyping and genetic analysis. The latter included screening for rare pathogenic variants in epilepsy genes, and polygenic risk score (PRS) calculation for ...
Genevieve Rayner   +4 more
wiley   +1 more source

Lupus cardiomyopathy in young woman with high lupus activity [PDF]

open access: yesБългарска кардиология
Systemic lupus erythematosus is a chronic autoimmune disorder affecting predominantly young women. Cardiac involvement in systemic lupus erythematosus is common and the typical manifestations are pericarditis, myocarditis, valvular disease, coronary ...
A. Borizanova-Petkova   +5 more
doaj   +3 more sources

New Horizons for Multiple Sclerosis Therapy: 2025 and Beyond

open access: yesAnnals of Neurology, EarlyView.
The advances achieved against multiple sclerosis (MS) represent one of the great success stories of modern molecular medicine. The development of therapies with increasing selectivity and safety, guided by gains in understanding the fundamental immunology, neurobiology, genetics, and triggers of this disease, have broadened the traditional focus on ...
Joseph J. Sabatino Jr.   +2 more
wiley   +1 more source

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