Results 71 to 80 of about 304,324 (330)

Association between Toxoplasma gondii and systemic lupus erythematosus: A systematic review and meta-analysis

Journal of Translational Autoimmunity, 2022
Infecting approximately one-third of the world's population, the intraneuronal parasite Toxoplasma gondii has been associated with several autoimmune diseases.
Pierce Bassett, Brinley N. Zabriskie, Ashley Catchpole, Dawson Hedges   +3 more
doaj  

Persistent Facial Oedema and Erythema in a Woman, An Uncommon Manifestation of Chronic Cutaneous Lupus Erythematosus

European Journal of Case Reports in Internal Medicine, 2020
Manifestations of chronic cutaneous lupus erythematosus are variable. Periorbital and facial swelling occurs in dermatomyositis and systemic lupus, but it has been rarely reported as a manifestation of exclusively cutaneous lupus.
Mónica García-Arpa, María Rodríguez-Vázquez, David Bellido-Pastrana, Natalia Villasanti-Rivas, Marcos Carmona-Rodríguez   +4 more
doaj   +1 more source

Engineered Foxp1high Exosomes Ameliorates Systemic Lupus Erythematosus

Advanced Science, EarlyView.
This study presents a dual‐engineering strategy combining mesenchymal stem cell aggregation and Foxp1 overexpression to generate Foxp1high aggregation exosomes with enhanced immunomodulatory properties. These engineered exosomes exhibit immune organ targeting and superior efficacy in systemic lupus erythematosus treatment by promoting Treg ...
Luhan Niu, Qianmin Ou, Qianhui Ren, Zhengshi Li, Hongcheng Chen, Fangcao Lei, Xueli Mao, Songtao Shi, Zetao Chen, Wei Teng   +9 more
wiley   +1 more source

The classification of glomerulonephritis in systemic lupus erythematosus revisited.

Kidney International, 2004
The currently used classification reflects our understanding of the pathogenesis of the various forms of lupus nephritis, but clinicopathologic studies have revealed the need for improved categorization and terminology.
J. Weening, V. D’Agati, M. Schwartz, S. Seshan, C. Alpers, G. Appel, J. Balow, J. Bruijn, T. Cook, F. Ferrario, A. Fogo, E. Ginzler, L. Hebert, G. Hill, P. Hill, J. Jennette, N. Kong, P. Lesavre, M. Lockshin, L. Looi, H. Makino, L. A. Moura, Michio Nagata   +22 more
semanticscholar   +1 more source

Integrated Transcriptome and Metabolomics Analyses Show MYC as a Potential Therapeutic Target for Behçet's Uveitis

Advanced Science, EarlyView.
Integrated single‐cell transcriptomic and metabolomic analyses reveal that MYC‐driven glycolysis activates the PI3K‐AKT‐FOXO1 pathway, disrupting Th17/Treg balance and promoting uveitis. MYC inhibition restores immune homeostasis and alleviates disease symptoms.
He Li, Lei Zhu, Zhaohuai Li, Yihan Zhang, Genxian Zhang, Xuening Peng, Dongting Wu, Qi Jiang, Rong Wang, Renbing Jia, Song Guo Zheng, Wenru Su   +11 more
wiley   +1 more source

Alcohol, smoking and illicit drug use in pediatric systemic lupus erythematosus patients

Revista Brasileira de Reumatologia, 2016
Objective To evaluate alcohol, smoking and/or illicit drug use, and history of bullying in adolescent childhood-onset systemic lupus erythematosus and healthy controls. Methods 174 adolescents with pediatric rheumatic diseases were selected.
Marlon van Weelden, Lígia B. Queiroz, Daniela M.R. Lourenço, Katia Kozu, Benito Lourenço, Clovis A. Silva   +5 more
doaj   +1 more source

Type I Interferon Signaling Augments Autoimmunity in Neuromyelitis Optica Spectrum Disorder

Advanced Science, EarlyView.
The cGAS‐STING innate immune pathway is excessively activated both in peripheral monocytes and CNS microglia in patients with NMOSD, leading to an overproduction of IFN‐I. IFN‐I subsequently acts on AQP4‐specific autoreactive T cells. Blocking this pathway may offer novel therapeutic options for individuals with NMOSD.
Tian‐Xiang Zhang, Xiaoxiao Yang, Xue Gao, Xiaoshan Du, Xuegan Lian, Naiyuan Shao, Ye Liu, Zhenning Huang, Dongmei Jia, Alexander Y. L. Lau, Zhiguo Li, Zaal Kokaia, Fu‐Dong Shi, Chao Zhang   +13 more
wiley   +1 more source

Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance

Advanced Science, EarlyView.
Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai, Kefei Wu, Qi Lin, Zhenzhen Cao, Yankun Jia, Ping Zhu   +5 more
wiley   +1 more source

Acute pancreatitis as an initial presentation of systemic lupus erythematosus: a case report

Journal of Medical Case Reports
Background Systemic lupus erythematosus is a systemic autoimmune disease affecting different organ systems. Gastrointestinal symptoms in patients with systemic lupus erythematosus are common. But systemic lupus erythematosus-related acute pancreatitis is
Mengyu Li, Sutong Li
doaj   +1 more source

Clinical correlates and outcomes in a group of Puerto Ricans with systemic lupus erythematosus hospitalized due to severe infections

SAGE Open Medicine, 2018
Objective: Infections are a major cause of morbidity and mortality in systemic lupus erythematosus. Clinical outcomes of systemic lupus erythematosus patients hospitalized due to infections vary among different ethnic populations. Thus, we determined the
Patricia Jordán-González, Lee Ming Shum, Lorena González-Sepúlveda, Luis M Vilá   +3 more
doaj   +1 more source