Results 211 to 220 of about 28,304 (252)

The Impact of Social Inequities on Presentation of Juvenile-Onset Systemic Lupus Erythematosus at a Large Tertiary Center.

Journal of clinical rheumatology
OBJECTIVE The prevalence of juvenile-onset systemic lupus erythematosus (JSLE) differs by race/ethnicity with environmental, genetic, and social factors implicated in disease severity and outcomes. Yet, the role of social determinants of health (SDoH) in
Emily F Beil, M. Deguzman, A. Ramirez, C. Yildirim-Toruner, A. Oluyomi, Omar Rosales, Danielle Guffey, Eyal Muscal, E. Peckham-Gregory   +8 more
semanticscholar   +1 more source

Endocrine and metabolic comorbidities in juvenile-onset systemic lupus erythematosus

Frontiers in Medicine
Background and aims Juvenile-onset systemic lupus erythematosus (JSLE) is a chronic autoimmune disease affecting individuals under 18, causing multi-system impairment.
Su Jin Park, Moon Bae Ahn, Dae Chul Jeong   +2 more
semanticscholar   +1 more source

DcR3 Mutations in Patients with Juvenile-onset Systemic Lupus Erythematosus Lead to Enhanced Lymphocyte Proliferation

The Journal of Rheumatology, 2013
Objective.Previous studies suggested a role for the death decoy receptor 3 (DcR3) in the pathogenesis of adult systemic lupus erythematosus (SLE). We investigated the role of DcR3 in juvenile-onset SLE, to identify polymorphisms that might alter the function of this protein.Methods.DcR3 was measured in the serum of 61 patients with juvenile SLE.
Chayanin, Chokdeemeeboon, Pramuk, Ammarinthnukrowh, Siraprapa, Tongkobpetch, Chalurmpon, Srichomtong, Tawatchai, Deekajorndech, Pornpimol, Rianthavorn, Pornchai, Kingwattanakul, Yingyos, Avihingsanon, Helen L, Wright, Piyaporn, Akkahat, Voravee P, Hoven, Wanwimon, Mekboonsonglarp, Steven W, Edwards, Nattiya, Hirankarn, Kanya, Suphapeetiporn, Vorasuk, Shotelersuk   +15 more
openaire   +2 more sources

Significance of the weighted complement domain of the EULAR/ACR classification criteria in juvenile onset systemic lupus erythematosus

Lupus, 2023
Objective We aimed to compare the clinical and laboratory characteristics of patients with SLE according to the weighted complement status of the EULAR/ACR criteria and investigate whether different weighting of the complement status at disease onset is ...
H. Kısaoğlu, Ozge Baba, M. Kalyoncu
semanticscholar   +1 more source

Bone Mineral Density and Serum Vitamin D 25-hydroxyvitamin D Levels in Childhood- or Juvenile-onset Systemic Lupus Erythematosus: A Systematic Review and Meta-analysis

Academic and Clinical Pediatrics
Patients with systemic lupus erythematosus (SLE), particularly those with childhood or juvenile onset, face a higher risk of complications due to low bone mineral density (BMD) and reduced serum Vitamin D levels. The aim of this study was to
Leonardo Alpha Diaz, Vanessa Els, Ni Wayan Puspita Sari, Madeline Juliand Sitranata, R. Suteja, Ketut Dewi Kumara Wati   +5 more
semanticscholar   +1 more source

Genetic and epigenetic factors shape phenotypes and outcomes in systemic lupus erythematosus – focus on juvenile-onset systemic lupus erythematosus

Current Opinion in Rheumatology
Purpose of review Systemic lupus erythematosus (SLE) is a severe autoimmune/inflammatory disease. Patients with juvenile disease-onset and those of non-European ancestry are most severely affected.
A. Charras, Linda T Hiraki, Laura B Lewandowski, C. Hedrich   +3 more
semanticscholar   +1 more source

A systematic review of pharmacological therapies and their effectiveness on health-related quality of life outcomes in patients with juvenile-onset systemic lupus erythematosus

Lupus, 2020
Juvenile-onset systemic lupus erythematosus (JSLE) presents with an aggressive course and high morbidity associated with disease and treatment. JSLE patients have a poorer health-related quality of life (HRQoL) when compared with age-matched patients ...
Dahima Cintron, J. M. Alanís, N. Álvarez-Villalobos, Rene Rodriguez-Gutierrez, Rene Rodriguez-Gutierrez, Luis M. Vilá   +5 more
semanticscholar   +1 more source

FRI0432 Comparison of Pregnancy Outcomes in Women with Juvenile and Adult Onset Systemic Lupus Erythematosus

Annals of the Rheumatic Diseases, 2014
Background Juvenile-onset systemic lupus erythematosus (JSLE) is characterized by severe organ involvement. Information about pregnancy in these patients is very limited. Objectives Compare the maternal and fetal outcomes in women with juvenile-onset systemic lupus erythematosus (JSLE) with adult-onset SLE (ASLE).
M.A. Saavedra, P. Cruz-Dominguez, S. Morales, A. Sanchez, L.J. Jara   +4 more
openaire   +1 more source

A Study on Semaphorin 3A Level in Juvenile-onset Systemic Lupus Erythematosus Patients.

Current Rheumatology Reviews
BACKGROUND Juvenile-onset systemic lupus erythematosus (jSLE) is an uncommon yet severe autoimmune/inflammatory condition affecting multiple bodily systems, typically manifest-ing before the age of 18.
Huda Marzouk, Dina Hesham Ahmed, Hend Mohamed Abu Shady, Hussien Tarek Abdelrahman Sarhan, Mohamed Salah Eldin Mohamed AbdelKader   +4 more
semanticscholar   +1 more source

Serious infections and tuberculosis adversely impact outcomes of juvenile onset systemic lupus erythematosus in India

Lupus
Background Infections are a major cause of morbidity and mortality in juvenile systemic lupus erythematosus (SLE). We assessed the incidence and risk factors for major infections in juvenile SLE. Methods A retrospective review of 225 patients of juvenile
Rudrarpan Chatterjee, S. Pattanaik, D. Misra, V. Agarwal, Able Lawrence, Ramnath Misra, A. Aggarwal   +6 more
semanticscholar   +1 more source