Results 71 to 80 of about 28,304 (252)

Disease characteristics in patients with juvenile- and adult-onset systemic lupus erythematosus: A multi-center comparative study

Archives of Rheumatology, 2022
Objectives: This study aims to compare disease characteristics in patients with juvenile-onset systemic lupus erythematosus (JSLE) and adult-onset systemic lupus erythematosus (ASLE). Patients and methods: Between June 2010 and March 2020, a total of 186 patients with JSLE (23 males, 163 females; median age: 25 years; range, 20 to 30.3 years) and 236 ...
Gamal, Sherif M, Fouad, Nermeen, Yosry, Nora, Badr, Wael, Sobhy, Nesreen   +4 more
openaire   +3 more sources

Diagnostic performance and clinical associations of antibodies to the chromatin antigenic system in juvenile systemic lupus erythematosus [PDF]

, 2012
OBJECTIVES: To determine the frequency of antibodies to chromatin components in juvenile systemic lupus erythematosus (JSLE), and to correlate the presence of these autoantibodies with clinical manifestations and disease activity. METHODS: Anti-chromatin
Andrade, Luiz Eduardo Coelho [UNIFESP], Hilário, Maria Odete Esteves [UNIFESP], Keusseyan, Silene Peres [UNIFESP], Okuda, Eunice Mitiko, Silva, Neusa Pereira da [UNIFESP], Terreri, Maria Teresa Ramos Ascensão [UNIFESP]   +5 more
core   +2 more sources

Serum Cytokine Profiling Differentiates Underlying Diseases in Cytokine Storm Syndrome

Arthritis &Rheumatology, EarlyView.
Serum cytokine profiling was performed using Luminex (48 cytokines) and ELISA (5 cytokines). Assessment of key cytokines (IFN‐α, IL‐18, IL‐6, CXCL9) delineated five dominant inflammatory patterns: I, IFN‐α–dominant CSS; II, IL‐18–dominant CSS; III, IL‐6–dominant CSS; IV, IFN‐γ–dominant CSS; and V, IL‐6 & IFN‐γ intermediate CSS.
Shuya Kaneko, Maho Hatano, Asami Shimbo, Futaba Miyaoka, Hitoshi Irabu, Yuko Akutsu, Yuko Hayashi, Mao Mizuta, Yasuo Nakagishi, Keiji Akamine, Naomi Iwata, Kenji Furuno, Takayuki Tanaka, Kazuyuki Ueno, Shuhei Fujita, Koji Yokoyama, Toshinori Minato, Kazushi Izawa, Takahiro Yasumi, Tadashi Matsubayashi, Tadashi Hosoya, Hiroki Nishikawa, Junya Fujimura, Ryoko Asano, Yuko Sugita, Kenichi Watanabe, Anna Kobayashi, Takuya Endo, Katsuhide Eguchi, Ryuta Nishikomori, Ryuhei Yasuoka, Takaki Asano, Miyako Kanno, Kazuya Hamada, Yuji Fujita, Daisuke Hayashi, Shojiro Watanabe, Takeshi Shiba, Shinsuke Yasuda, Masaaki Mori, Hirokazu Kanegane, Masatoshi Takagi, Masaki Shimizu   +42 more
wiley   +1 more source

Juvenile idiopathic inflammatory myopathies: the value of magnetic resonance imaging in the detection of muscle involvement [PDF]

, 2000
CONTEXT: One of the major current challenges related to juvenile idiopathic inflammatory myopathy is the search for highly sensitive and specific non-invasive methods for diagnosis as well as for follow-up.
Hilário, Maria Odete Esteves, Lederman, Henrique Manoel, Len, Claudio Arnaldo, Lutti, Daniela, Terreri, Maria Teresa Ramos Ascensão, Yamashita, Helio Kiitiro   +5 more
core   +4 more sources

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Mental disorders in children with rheumatic diseases

Научно-практическая ревматология
The prevalence of concomitant mental disorders in children with rheumatic diseases is notably higher than in the overall population. However, psychiatric comorbidity in pediatric rheumatology remains poorly understood, whereas approaches to mental ...
A. V. Santimov, S. V. Grechanyi, G. A. Novik   +2 more
doaj   +1 more source

Cutaneous manifestations of juvenile onset lupus erythematosus: A clinical study

Indian Journal of Paediatric Dermatology, 2018
Introduction: Juvenile-onset systemic lupus erythematosus (SLE) is one of the most common systemic autoimmune connective tissue disorders in children.
Vinitha Panicker, Anil Mathew, Gopikrishnan Anjaneyan, Soumya Jagadeesan, S. Lekshmi, Jacob Thomas   +5 more
doaj   +1 more source

Neuropsychiatric lupus in Malaysian children: clinical characteristics, imaging features and 12-month outcomes

The Turkish Journal of Pediatrics, 2021
Background. Neuropsychiatric lupus (NPSLE) serves as a marker of severe disease in children with juvenile onset systemic lupus erythematosus (JSLE). This study aims to characterise the clinical and imaging features at diagnosis; and outcomes after
Sern Chin Lim, Yusma Lyana Md-Yusof, Bushra Johari, Roqiah Fatmawati Abdul-Kadir, Swee Ping Tang   +4 more
doaj   +1 more source

Depression and anxiety and their association with healthcare utilization in pediatric lupus and mixed connective tissue disease patients: a cross-sectional study [PDF]

, 2014
Background Depression and anxiety adversely affects outcomes in systemic lupus erythematosus (SLE) and healthcare utilization is high for pediatric SLE.
Gerdes, Marsha, Gutstein, Allyson, Keren, Ron, Knight, Andrea, Morales, Knashawn, Vickery, Michelle, Wise, Pamela   +6 more
core   +1 more source

Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus: Data from the UK Juvenile-onset systemic lupus erythematosus cohort study

Lupus, 2021
Introduction Juvenile-onset systemic lupus erythematosus (JSLE) is a rare autoimmune/inflammatory disease with significant morbidity and mortality.
T. Giani, E. Smith, E. Al-Abadi, K. Armon, K. Bailey, C. Ciurtin, J. Davidson, J. Gardner-Medwin, K. Haslam, D. Hawley, A. Leahy, V. Leone, F. McErlane, D. Mewar, G. Modgil, R. Moots, C. Pilkington, F. Pregnolato, A. Ramanan, S. Rangaraj, P. Riley, A. Sridhar, N. Wilkinson, R. Cimaz, M. Beresford, C. Hedrich   +25 more
semanticscholar   +1 more source