Results 81 to 90 of about 67,974,619 (226)

Endocrine and metabolic comorbidities in juvenile-onset systemic lupus erythematosus

Frontiers in Medicine
Background and aimsJuvenile-onset systemic lupus erythematosus (JSLE) is a chronic autoimmune disease affecting individuals under 18, causing multi-system impairment. Patients with JSLE exhibit more severe disease when compared to patients with adult-onset SLE.
Su Jin Park, Moon Bae Ahn, Dae Chul Jeong   +2 more
openaire   +3 more sources

Eating disorders in children with rheumatic diseases

Научно-практическая ревматология
The high comorbidity of eating disorders, especially anorexia nervosa, and various autoimmune diseases is well known but only a few foreign publications address the prevalence and course of eating disorders in children with immuneinflammatory rheumatic ...
A. V. Santimov, S. V. Grechanyi, G. A. Novik, M. V. Zhdanova, N. V. Slizovskii   +4 more
doaj   +1 more source

Association of STAT4 gene single nucleotide polymorphisms with Iranian juvenile-onset systemic lupus erythematosus patients

The Turkish Journal of Pediatrics, 2017
Juvenile-onset systemic lupus erythematosus (JSLE) is a complex autoimmune disease, characterized by multi-organ involvement. Single nucleotide polymorphisms (SNPs) of signal transducer and activator of transcription 4 (STAT4) gene have been reported to
Arash Salmaninejad, Mahdi Mahmoudi, Saeed Aslani, Shiva Poursani, Vahid Ziaee, Nima Rezaei   +5 more
doaj   +1 more source

Precision immunomodulation for pediatric hemophagocytic lymphohistiocytosis in intensive care

Pediatric Investigation, EarlyView.
This review presents a bedside framework for recognizing pediatric hemophagocytic lymphohistiocytosis and cytokine storm, stabilizing organ dysfunction, identifying the underlying phenotype, selecting targeted immunomodulation, considering extracorporeal adjuncts, and reassessing response within 24–72 h. ABSTRACT Hemophagocytic lymphohistiocytosis (HLH)
Weerapong Lilitwat, Prakreeti Bhandari
wiley   +1 more source

Effects of rituximab-based B-cell depletion therapy on skin manifestations of lupus erythematosus--report of 17 cases and review of the literature [PDF]

, 2013
Cutaneous manifestations occur frequently in systemic lupus erythematosus (SLE) and are pathognomonic in subacute-cutaneous lupus erythematosus (SCLE) and chronic cutaneous lupus erythematosus (CCLE).
Morris, SD, Hofmann, SC, Leandro, MJ, Isenberg, DA   +3 more
core  

Toll‐Like Receptor 4 Signaling in Natural N‐Acylethanolamines and Derivative NAE‐Like Compounds: Mechanisms and Implications for Neuroimmune and Inflammatory Processes in a Systematic Search Approach

Phytotherapy Research, EarlyView.
ABSTRACT N‐acylethanolamines (NAEs) are endogenous fatty acid amides structurally related to the endocannabinoid anandamide and function as bioactive lipid mediators with broad regulatory roles in inflammation and neuroinflammation. Among pattern‐recognition receptors, Toll‐like receptor 4 (TLR4) occupies a central position in innate immune ...
Damiana Scuteri, Francesca Guida, Giacinto Bagetta, Sabatino Maione, Maria Tiziana Corasaniti, Morena Zusso   +5 more
wiley   +1 more source

Multicenter Clinical Comparison Between Anti‐NXP2 and Anti‐TIF1‐γ Antibody‐Positive Myositis, and Analysis of the Clinical Significance of Anti‐NXP2 Antibody Titers in Idiopathic Inflammatory Myopathies

The Journal of Dermatology, EarlyView.
ABSTRACT We aimed to measure anti‐nuclear matrix protein 2 antibody (anti‐NXP2) titers in patients with anti‐NXP2‐positive idiopathic inflammatory myopathies, investigate whether these titers are associated with clinical manifestations, malignancy risk, and treatment response, and compare the clinical and serological features between anti‐NXP2‐positive
Satoshi Kamiya, Mariko Ogawa‐Momohara, Yoshinao Muro, Yuta Yamashita, Satoko Yuasa, Masato Kakeda, Kimiko Nakajima, Hiroyuki Morita, Mitsuyo Kinjo, Takako Hashimoto, Ken Yoshida, Takuya Takeichi, Haruka Koizumi, Norika Akashi, Eori Noda, Masashi Akiyama   +15 more
wiley   +1 more source

Revisiting Childhood-Onset Systemic Lupus Erythematosus

Childhood-onset systemic lupus erythematosus (cSLE) is a chronic autoimmune disease with a multisystemic involvement diagnosed during childhood. The disease is marked by the production of autoantibodies targeting self-antigens, often before symptoms ...
Pınar Özge Avar-Aydın, Hermine I. Brunner   +1 more
core   +1 more source

Childhood-onset bullous systemic lupus erythematosus

, 2014
Bullous systemic lupus erythematosus has rarely been described in pediatric lupus population and the real prevalence of childhood-onset bullous systemic lupus erythematosus has not been reported.
Campos, L. M. A., Romiti, R., Aikawa, N. E., Lourenco, D. M. R., Gomes, R. Cunha, Silva, C. A.   +5 more
core   +1 more source

Fibrillar‐Type Dermatitis Herpetiformis: An Underrecognized Variant That Is Rarely Associated With Celiac Disease and Lacking Epidermal Transglutaminase Deposition: A Report of Two Cases

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Dermatitis herpetiformis (DH) is a rare, intensely pruritic cutaneous manifestation of celiac disease (CD), typically presenting with excoriated papulovesicular lesions on extensor surfaces. DH is associated with IgA autoantibodies against epidermal transglutaminase (eTG), which form granular immune deposits in the papillary dermis and induce ...
Jeffrey Damman, Elodie Mendels, Sven van der Woude, Sharon Veenbergen, Gilles F. H. Diercks, Martijn B. van Doorn   +5 more
wiley   +1 more source