Results 101 to 110 of about 53,292,385 (218)

Juvenile and juvenile-onset systemic lupus erythematosus patients: Clinical characteristics, disease activity and damage

Egyptian Pediatric Association Gazette, 2017
Background: The diagnosis of systemic lupus erythematosus (SLE) in children is challenging. The heterogeneous manifestations and disease impact on the child’s growth highlight the importance of timely diagnosis and management.
Rasha E. Gheith, Iman I. El-Gazzar, Hussein S. El Fishawy, Abeer M. Nour El-Din, Dina M.R. Bahgat, Tamer A. Gheita   +5 more
doaj   +1 more source

Heterogeneity of macrophage activation syndrome and treatment progression

Frontiers in Immunology
Macrophage activation syndrome (MAS) is a rare complication of autoimmune inflammatory rheumatic diseases (AIIRD) characterized by a progressive and life-threatening condition with features including cytokine storm and hemophagocytosis.
Yuanji Dong, Ting Wang, Huaxiang Wu
doaj   +1 more source

Use of rituximab in systemic lupus erythematosus in children: a review

Научно-практическая ревматология, 2019
Juvenile-onset  systemic lupus erythematosus (SLE) is a significant and urgent problem in the practice of pediatricians and rheumatologists  in both verifying its diagnosis and choosing treatment policies, by taking into account the features of the onset,
A. N. Arefyeva
doaj   +1 more source

Case report: Single infusion of combined anti-CD20 and anti-CD38 monoclonal antibodies in pediatric refractory lupus nephritis

Frontiers in Immunology
Lupus nephritis (LN), present in 30%–50% of systemic lupus erythematosus (SLE) patients, often necessitates standard immunosuppressive therapy (glucocorticoids, MMF, CYC) as suggested by the European League Against Rheumatism/European Renal Association ...
Decimo Silvio Chiarenza, Raul Mancini, Carolina Bigatti, Carolina Bigatti, Gianluca Caridi, Alessandro Consolaro, Alessandro Consolaro, Valentina Natoli, Valentina Natoli, Gabriele Mortari, Xhuliana Kajana, Francesca Lugani, Marco Gattorno, Marco Gattorno, Gian Marco Ghiggeri, Edoardo La Porta, Gabriele Gaggero, Enrico E. Verrina, Andrea Angeletti   +18 more
doaj   +1 more source

Pharmacological Treatment of Systemic Lupus Erythematosus

, 2022
The aim of this thesis is to review and explain the possible treatments of Systemic Lupus Erythematosus. This thesis takes a dive in the possible pharmacological treatments present and developing treatments for SLE.hbkáltalános orvosangolegységes ...
Sager, Motasem
core  

Comparison of estimates of body fat content in childhood-onset systemic lupus erythematosus

, 2017
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)We aimed to compare estimates of body fat content with respect to their ability to predict the percentage of body fat, confirmed by dual-energy X-ray absorptiometry scans in childhood ...
Peres, F. A., Ramos, C. D., Santos, A. de Oliveira, Appenzeller, S., Sinicato, N. A., Pelicari, K. de Oliveira, Marini, R.   +6 more
core   +1 more source

Antiphospholipid Syndrome: Expanding the Spectrum of Autoimmune Thrombosis [PDF]

, 2007
[eng] The antiphospholipid syndrome (APS) is an acquired prothrombotic syndrome characterized by venous or arterial thromboses and pregnancy morbidity.
Gómez-Puerta, José Alfredo
core   +2 more sources

Damage index in childhood-onset systemic lupus erythematosus in Egypt

Pediatric Rheumatology Online Journal, 2011
Background To investigate the prevalence of cumulative organ damage among Egyptian children with juvenile-onset systemic lupus erythematosus (jSLE) and the relationships between the organ damage and the demographic data, clinical variables, and disease ...
Salah Samia, Lotfy Hala M, Mokbel Abir N, Kaddah Ahmed M, Fahmy Nouran   +4 more
doaj   +1 more source

Clinical presentations and outcomes of Filipino juvenile systemic lupus erythematosus

Pediatric Rheumatology Online Journal, 2011
Objective Juvenile Systemic Lupus Erythematosus (SLE) varies by location and ethnicity. This study describes the clinical, laboratory profile and outcome of juvenile SLE seen at Philippine General Hospital (PGH) from 2004-2008.
Dans Leonila F, Gulay Carien B
doaj   +1 more source

Juvenile-onset Systemic Lupus Erythematosus: Recent Advances in Pathogenesis and Treatment

Current Rheumatology Reports
Abstract Purpose of Review This review summarizes recent advances in understanding the pathogenesis and therapeutic landscape of juvenile-onset systemic lupus erythematosus (jSLE), with a focus on how emerging genetic and immunologic insights inform patient stratification, targeted treatments ...
Natoli, Valentina, Charras, Amandine, Smith, Eve MD, Hedrich, Christian M.   +3 more
openaire   +2 more sources