Results 121 to 130 of about 53,292,385 (218)

Genetic and epigenetic factors shape phenotypes and outcomes in systemic lupus erythematosus – focus on juvenile-onset systemic lupus erythematosus

Current Opinion in Rheumatology
Purpose of review Systemic lupus erythematosus (SLE) is a severe autoimmune/inflammatory disease. Patients with juvenile disease-onset and those of non-European ancestry are most severely affected. While the exact pathophysiology remains unknown, common and rare gene variants in the context of environmental exposure and ...
Charras, Amandine, Hiraki, Linda T., Lewandowski, Laura, Hedrich, Christian M.   +3 more
openaire   +2 more sources

A case of Juvenile Systemic Lupus Erythematosus in a pre-pubertal child with atopic eczema

Journal of the Pakistan Medical Association
Juvenile Systemic Lupus Erythematosus (JSLE) is a subset of SLE, with onset before eighteen years of age and associated with increased mortality and morbidity. JSLE is a complex autoimmune disease with respect to its underlying genetics.
Ghazal Afzal, Shakila Junaid, Fatima Zahoor   +2 more
doaj   +1 more source

Kikuchi-Fujimoto disease and systemic lupus erythematosus

, 2016
Diego F Baenas,1 Fernando A Diehl,1 María J Haye Salinas,2 Verónica Riva,3 Ana Diller,3 Pablo A Lemos1,4 1Clinical Medicine Department, 2Rheumatology Department, 3Pathology Department, Hospital Privado Universitario de Córdoba ...
Baenas DF, Riva V, Diehl FA, Haye Salinas MJ, Lemos PA, Diller A   +5 more
core  

Cognitive functions and autoantibodies in patients with systemic lupus erythematosus

, 2016
Introduction: Autoantibodies may occur in the course of various diseases. In the case of systemic lupus erythematosus the presence of specific autoantibodies is included in the classification criteria of the disease.
Ewa Robak, Jakub Ząbek, Tomasz Sobów, Jarosław Bogaczewicz, Anna Woźniacka, Anna Bogaczewicz   +5 more
core   +1 more source

Systemic lupus erythematosus presented as hemorrhagic pericardial effusion with cardiac tamponade: a case report

, 2014
Hemorrhagic pericardial effusion with cardiac tamponade as the earliest clinical manifestation of systemic lupus erythematosus is distinctly uncommon.
Ng, Fei Yin, Gew, Lai Teck, A., Pravindh, Hoo, Fan Kee   +3 more
core   +1 more source

Treatment of systemic-onset juvenile arthritis with canakinumab

, 2015
Joachim Peitz, Gerd Horneff Pediatric Rheumatology Centre, Department of General Pediatrics and Neonatology, Asklepios Clinic, Sankt Augustin, Germany Abstract: Treatment of systemic-onset juvenile idiopathic arthritis is challenging, but the ...
Horneff G, Peitz J
core  

Combination Therapy of Plasmapheresis with Intravenous Cyclophosphamide and Rituximab in a Case of Juvenile-onset Systemic Lupus Erythematosus (SLE) Accompanied by Secondary Thrombotic Microangiopathy (TMA): A Case Report

Journal of Clinical Rheumatology and Immunology
Background: Thrombotic microangiopathy (TMA), a severe syndrome of microangiopathic haemolytic anaemia, thrombocytopenia, and end-organ damage, is an uncommon complication of Systemic Lupus Erythematosus (SLE), particularly with lupus nephritis.
Hiu Ching Kwong
doaj   +1 more source

Case report Heart failure with complete recovery in a patient with systemic lupus erythematosus

, 2015
We report the case of a 43-year-old female patient who was admitted to the Cardiology Department from the Rheumatology Clinic where she was being treated for multi-organ serositis, fatigue and mild dyspnoea on exertion.
Themistoklis Iliopoulos, Konstantinos Lampropoulos, Dimitrios Kotsas   +2 more
core   +1 more source

Characterizing juvenile-onset systemic lupus erythematosus: clinical outcomes, disease progression, and determinants in pediatric populations [PDF]

ARP Rheumatology
Introduction: This study aims to delineate the sociodemographic, clinical, and laboratory characteristics of juvenile-onset systemic lupus erythematosus (jSLE) patients.
Gülcan Ozomay Baykal, Betül Sözeri
doaj  

Reduced expressions of apoptosis-related proteins TRAIL, Bcl-2, and TNFR1 in NK cells of juvenile-onset systemic lupus erythematosus patients: relations with disease activity, nephritis, and neuropsychiatric involvement

Frontiers in Immunology
BackgroundLupus pathogenesis is mainly ascribed to increased production and/or impaired clearance of dead cell debris. Although self-reactive T and B lymphocytes are critically linked to lupus development, neutrophils, monocytes, and natural killer (NK ...
Bernadete L. Liphaus, Bernadete L. Liphaus, Simone C. Silva, Patrícia Palmeira, Clovis A. Silva, Clovis A. Silva, Claudia Goldenstein-Schainberg, Magda Carneiro-Sampaio   +7 more
doaj   +1 more source