Results 121 to 130 of about 67,974,619 (226)

Modern treatment options for systemic lupus erythematosus in children (literature review)

Современная ревматология
The treatment of juvenile-onset systemic lupus erythematosus (jSLE) is a complex task in view of the diversity of clinical manifestations and the course of the disease as well as the high risk of organ damage.
M. I. Kaleda, I. P. Nikishina
doaj   +1 more source

Juvenile lupus-like with negative serology: a clinical dilemma and diagnostic challenge

Journal of Rheumatic Diseases
Systemic lupus erythematosus (SLE) is an autoimmune disorder that can affect various organs. Juvenile-onset SLE (jSLE) may be more severe than the adult-onset form, but the diagnosis and classification remain challenging due to the complex nature of the ...
Alhanouf Adnan Alsharif, Abdulaziz Marzouq Almutairi, Emtenan Badar Basahl, Abdulaziz Abdulllah Alshathri, Jameela Abdulaziz Kari, Mohammed Ahmad Shalaby, Mohammed Ahmad Nashawi   +6 more
doaj   +1 more source

The future of Korean rheumatology

Journal of Rheumatic Diseases
Systemic lupus erythematosus (SLE) is an autoimmune disorder that can affect various organs. Juvenile-onset SLE (jSLE) may be more severe than the adult-onset form, but the diagnosis and classification remain challenging due to the complex nature of the ...
Bon San Koo, Jae-Bum Jun
doaj   +1 more source

Associations of Raynaud's Phenomenon in Juvenile Onset Systemic Lupus Erythematosus

Van Medical Journal
INTRODUCTION: Raynaud's phenomenon (RP) is associated with mild disease in adults with systemic lupus erythematosus (SLE). Although RP is more frequently reported in juvenile onset SLE (jSLE) clinical associations were not studied. We aimed to investigate whether the presence of RP is associated with clinical and serological features at onset and ...
Özge Baba, Hakan Kısaoğlu, Mukaddes Kalyoncu   +2 more
openaire   +2 more sources

OA21 Juvenile onset systemic lupus erythematosus: a pair of siblings

Rheumatology Advances in Practice
Abstract Introduction We present the cases of two siblings both of whom were born in Goa to non-consanguineous parents with juvenile onset systemic lupus erythematosus (jSLE) with differing clinical and laboratory features.
Waller, Rosemary, Turtsevich, Inga
openaire   +1 more source

Genetic and epigenetic factors shape phenotypes and outcomes in systemic lupus erythematosus – focus on juvenile-onset systemic lupus erythematosus

Current Opinion in Rheumatology
Purpose of review Systemic lupus erythematosus (SLE) is a severe autoimmune/inflammatory disease. Patients with juvenile disease-onset and those of non-European ancestry are most severely affected. While the exact pathophysiology remains unknown, common and rare gene variants in the context of environmental exposure and ...
Charras, Amandine, Hiraki, Linda T., Lewandowski, Laura, Hedrich, Christian M.   +3 more
openaire   +2 more sources

A case of Juvenile Systemic Lupus Erythematosus in a pre-pubertal child with atopic eczema

Journal of the Pakistan Medical Association
Juvenile Systemic Lupus Erythematosus (JSLE) is a subset of SLE, with onset before eighteen years of age and associated with increased mortality and morbidity. JSLE is a complex autoimmune disease with respect to its underlying genetics.
Ghazal Afzal, Shakila Junaid, Fatima Zahoor   +2 more
doaj   +1 more source

Supplemental material for Aquaporin-4 IgG antibody-related disorders in patients with juvenile systemic lupus erythematosus

, 2019
Supplemental Material for Aquaporin-4 IgG antibody-related disorders in patients with juvenile systemic lupus erythematosus by E Moraitis, Y Stathopoulos, Y Hong, M Al-Obaidi, K Mankad, Y Hacohen, D Sen, C Hemingway and D Eleftheriou in ...
K Mankad (6860402), D Eleftheriou (3526691), D Sen (6860408), Y Hacohen (6860405), M Al-Obaidi (6860399), E Moraitis (6860390), Y Hong (6860396), Y Stathopoulos (6860393), C Hemingway (6860411)   +8 more
core   +1 more source

Cytokines in relation to autoantibodies before onset of symptoms for systemic lupus erythematosus

, 2014
Objectives: A number of cytokines and chemokines were analysed and related to autoantibodies in blood samples pre-dating the onset of symptoms of systemic lupus erythematosus.
Eriksson, Catharina,, Rantapää Dahlqvist, Solbritt,   +1 more
core   +1 more source

An investigation of the molecular basis of interactions between human monoclonal antibodies and antigens that are clinically relevant in systemic lupus erythematosus and the Antiphospholipid Syndrome. [PDF]

, 2007
Autontibodies to a wide variety of antigens are associated with systemic lupus erythematosus (SLE) and the Antiphospholipid Syndrome (APS).
Lambrianides, A.
core