Severe Juvenile-Onset Systemic Lupus Erythematosus: A Case Series-Based Review and Update [PDF]
Children, 2023 Juvenile-onset systemic lupus erythematosus (jSLE) is a multisystemic disease diagnosed in young patients based on the clinical criteria of the European League Against Rheumatism (EULAR) and the American College of Rheumatology (ACR).
Sergi Huerta-Calpe +4 more
doaj +4 more sources
Endocrine and metabolic comorbidities in juvenile-onset systemic lupus erythematosus [PDF]
Frontiers in MedicineBackground and aimsJuvenile-onset systemic lupus erythematosus (JSLE) is a chronic autoimmune disease affecting individuals under 18, causing multi-system impairment.
Su Jin Park +2 more
doaj +4 more sources
Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus (jSLE) [PDF]
Molecular and Cellular Pediatrics, 2023 Systemic lupus erythematosus (SLE) is a rare autoimmune/inflammatory disease with significant morbidity and mortality. Approximately 15–20% of SLE patients develop the disease during childhood or adolescence (juvenile-onset SLE/jSLE).
Valentina Natoli +3 more
doaj +2 more sources
The role of assessment of renal biopsy in electron microscopy in making a diagnosis of juvenile-onset systemic lupus erythematosus in a 16-year-old female patient with depression and proteinuria – case report [PDF]
Central European Journal of Immunology, 2022 The course of juvenile-onset systemic lupus erythematosus may vary, from rapid multiorgan involvement to insidious development mimicking different medical conditions.
Tomasz Koszutski +4 more
doaj +2 more sources
The role of hsa_circ_0008945 in juvenile-onset systemic lupus erythematosus [PDF]
BMC Medical Genomics, 2023 Background circular RNAs (circRNAs) play a crucial role in many physiological and pathological processes including juvenile-onset systemic lupus erythematosus (JSLE).
Qifan Wang +6 more
doaj +2 more sources
Autoantibody-based subgroups and longitudinal seroconversion in juvenile-onset systemic lupus erythematosus [PDF]
Lupus Science and Medicine, 2023 Objective To explore the clinical value of autoantibody-based subgroup framework and the trend of autoantibody fluctuation in juvenile-onset SLE (JSLE).Methods Eighty-seven patients with JSLE were retrospectively collected and divided into subgroups via ...
Zhen Yang +8 more
doaj +2 more sources
Vasculitis in Juvenile-Onset Systemic Lupus Erythematosus [PDF]
Frontiers in Pediatrics, 2019 Juvenile-onset systemic lupus erythematosus (JSLE) is a rare, heterogeneous multisystem autoimmune disease that can affect any organ, and present with diverse clinical and serological manifestations. Vasculitis can be a feature of JSLE.
Eve M. D. Smith +4 more
doaj +2 more sources
Neuropsychiatric Involvement in Juvenile-Onset Systemic Lupus Erythematosus [PDF]
Neurology Research International, 2018 Objective. Systemic lupus erythematosus (SLE) is a complex autoimmune disorder characterized by multisystem involvement, including the nervous system.
Mohammad-Amin Khajezadeh +5 more
doaj +2 more sources
Dysregulation of complement factor H in juvenile-onset systemic lupus erythematosus patients [PDF]
The Turkish Journal of Gastroenterology, 2022 Objectives: This study aims to evaluate the expression pattern of factor H in peripheral blood and the frequency of factor H autoantibodies in plasma of juvenile-onset systemic lupus erythematosus (jSLE) patients compared to healthy controls ...
Eman Eissa +3 more
doaj +2 more sources
Nailfold capillary phenotypes distinguish juvenile myositis subtypes and associate with disease activity. [PDF]
Clin Transl MedNailfold capillaroscopy is a non‐invasive imaging tool that can aid in the diagnosis and monitoring of juvenile myositis. Branched nailfold capillary morphology is more common in juvenile myositis patients, particularly those positive for TIF1γ+ autoantibodies. Juvenile myositis patients with more active disease demonstrate increased microhaemorrhages,
McClellan N +7 more
europepmc +2 more sources