Results 41 to 50 of about 2,000,650 (198)

Impact of disease activity on health-related quality of life in systemic lupus erythematosus – a cross-sectional analysis of the Swiss Systemic Lupus Erythematosus Cohort Study (SSCS) [PDF]

open access: yes, 2017
Background To assess the impact of disease activity on health-related quality of life (HRQoL) in systemic lupus erythematosus (SLE). Methods Cross-sectional study of patients included in the Swiss SLE Cohort Study between April 2007 and June 2014.
Eric Dayer   +38 more
core   +2 more sources

Juvenile and juvenile-onset systemic lupus erythematosus patients: Clinical characteristics, disease activity and damage

open access: yesEgyptian Pediatric Association Gazette, 2017
Background: The diagnosis of systemic lupus erythematosus (SLE) in children is challenging. The heterogeneous manifestations and disease impact on the child’s growth highlight the importance of timely diagnosis and management.
Rasha E. Gheith   +5 more
doaj   +1 more source

Bone mineral density in juvenile onset Systemic lupus erythematosus

open access: yesIndian Pediatrics, 2015
To compare bone mineral density in patients with juvenile-onset Systemic lupus erythematosus and healthy controls.Serial bone mineral density measurements in 27 patients with juvenile-onset systemic lupus were compared to 97 healthy age-matched controls.All patients with juvenile-onset had low bone mineral density scores at initial assessment that ...
R, Abdwani   +4 more
openaire   +2 more sources

The Swiss Systemic lupus erythematosus Cohort Study (SSCS) - cross-sectional analysis of clinical characteristics and treatments across different medical disciplines in Switzerland [PDF]

open access: yes, 2014
OBJECTIVES: To describe disease characteristics and treatment modalities in a multidisciplinary cohort of systemic lupus erythematosus (SLE) patients in Switzerland.
Stoll, T.   +64 more
core   +1 more source

Exercise as adjunctive therapy for systemic lupus erythematosus [PDF]

open access: yes, 2021
This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To evaluate the safety and effectiveness of structured exercise interventions for adults with systemic lupus ...
Greene, David   +7 more
core   +1 more source

Case Report: Novel UNC93B1 variant causes rheumatoid arthritis and interstitial pneumonia

open access: yesFrontiers in Immunology
BackgroundUNC93B1 is a transmembrane protein essential for regulating toll-like receptors (TLRs). Pathogenic variants in human UNC93B1 have recently been described in a limited number of patients with childhood systemic lupus erythematosus and chilblain ...
Tingyan He   +6 more
doaj   +1 more source

Off-label use of tocilizumab to treat non-juvenile idiopathic arthritis in pediatric rheumatic patients: a literature review

open access: yesPediatric Rheumatology Online Journal, 2018
Tocilizumab, an anti-interleukin-6 (IL-6) agent, is indicated as a treatment for several autoimmune or inflammatory diseases, including rheumatoid arthritis and juvenile idiopathic arthritis (JIA). IL-6 plays roles in both immune system dysregulation and
Ju-Yang Jung   +3 more
doaj   +1 more source

Association of rs7574865 G/T polymorphism of STAT4 gene with juvenile onset of systemic lupus erythematosus

open access: yesСовременная ревматология, 2022
Systemic lupus erythematosus (SLE) with juvenile onset (jSLE) is a complex autoimmune disease involving many organs and systems. The single nucleotide polymorphism rs7574865 of the STAT4 (signal switch and transcription activator 4) gene is associated ...
M. Yu. Krylov   +4 more
doaj   +1 more source

Association between academic performance and cognitive dysfunction in patients with juvenile systemic lupus erythematosus

open access: yesRevista Brasileira de Reumatologia, 2016
Objective To determine whether there is an association between the profile of cognitive dysfunction and academic outcomes in patients with juvenile systemic lupus erythematosus (JSLE).
Renan Bazuco Frittoli   +5 more
doaj   +1 more source

Systemic lupus erythematosus organ manifestation and disease activity in children based on Mexican systemic lupus erythematosus disease activity index score at East Java, Indonesia

open access: yesIndian Journal of Rheumatology, 2021
Background: Disease activity in systemic lupus erythematosus (SLE) is associated with organ damage, outcome worsening, comorbidities, and mortalities in the patients.
Zahrah Hikmah   +2 more
doaj   +1 more source

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