Results 61 to 70 of about 2,000,650 (198)

AMETHYST: A Retrospective Cohort Study of Treatment Patterns and Outcomes in Patients With Glucocorticoid‐Refractory Macrophage Activation Syndrome Complicating Still's Disease

Arthritis &Rheumatology, EarlyView.
Objective Information is limited on the natural history and current treatment patterns in macrophage activation syndrome (MAS), a life‐threatening hyperinflammatory syndrome complicating Still's disease (systemic juvenile idiopathic arthritis [sJIA] and adult‐onset Still's disease [AOSD]).
Alexei Grom, Jordi Antón, Edward M. Behrens, Corey Best, Norbert Blank, Josefin Blomkvist, Scott W. Canna, Sonia Carriquí, Shanmuganathan Chandrakasan, Andrew Danquah, Ngoc‐Bao Duong, Brian D. Jamieson, Paivi Miettunen, Abiola Oladapo, Sampath Prahalad, Pierre Quartier, Grant Schulert, Anna Stoltenberg, Uwe Ullmann, Erika Van Nieuwenhove, Sebastiaan J. Vastert, Fabrizio De Benedetti   +21 more
wiley   +1 more source

The systemic lupus erythematosus IRF5 risk haplotype is associated with systemic sclerosis [PDF]

, 2013
Systemic sclerosis (SSc) is a fibrotic autoimmune disease in which the genetic component plays an important role. One of the strongest SSc association signals outside the human leukocyte antigen (HLA) region corresponds to interferon (IFN) regulatory ...
Schuerwegh, A. J., Alexander Kreuter (592), Herrick Ariane, Martín J., Carmona, F.D., Jacob M van Laar, Madelon C Vonk, Voskuyl AE, Denton C, Mónica Fernández-Castro, Martin Jose-Ezequiel, Hunzelmann Nicolas, Airó Paolo, Ariane Herrick (214049), Claudio Lunardi (12868), Paul Shiels (276244), Witte, T. de, Voskuyl Alexandre E., Distler, J.H., Riemekasten, Gabriela, H W Distler, Egurbide, María Victoria, Mónica Fernández-Castro (276238), Radstake TR, Camps, M.T., Egurbide, M. V., Simeón, C.P., Carreira, Patricia E., Airó, P., Kreuter, Alexander, Camps María Teresa, Airó, Paolo, Scorza, Raffaella, Martín, Javier, the Spanish Scleroderma Group, Nicolas Hunzelmann, Beltrán Emma, Madelon C. Vonk (213950), Torsten Witte, Javier Martín (2584444), Sáez-Comet, Luis, van Laar, J.M., María Teresa Camps, Callejas, J.L., Carmen Fonseca (214061), Airó P, Martin, J.E., Madhok, Rajan, Fernández Castro M, Kreuter, A., Herrick A, Carmen P. Simeón (5650816), Riemekasten Gabriela, Beltrán E, Radstake, T. R., Shiels, Paul G., Alexandre E. Voskuyl (213961), Carreira, P.E., Vonk, M.C., Lorenzo Beretta, Carreira PE, Hunzelmann N, Kreuter A, Patricia E. Carreira (276236), Beltrán, Emma, Carmona F. David, Rajan Madhok, Worthington J, Gabriela Riemekasten, Scorza R, Vonk MC, Simeón Carmen P., Witte, Torsten, Camps, María Teresa, Carmona FD, Herrick, A., Schuerwegh AJ, Paolo Airó, Distler, Jörg H W, Radstake Timothy R. D. J., Alexandre E Voskuyl, et al., José Luis Callejas (276237), Schuerwegh, Annemie J, Jane Worthington, Laar, Jacob M. van, Madhok R, Callejas, José Luis, Martín, J. E., Jacob M. van Laar (177818), Vonk Madelon C., Javier Martín, Beretta, Lorenzo, Emma Beltrá, Timothy R. D. J. Radstake (168224), Shiels Paul, Jörg H. W. Distler (3196062), Madhok Rajan, Callejas JL, Beltrán, E., Martin, Jose Ezequiel, Schuerwegh, A.J., Witte Torsten, Distler, J.H. W., Raffaella Scorza, Voskuyl, Alexandre E., Carmen P Simeón, Carmona, F David, Spanish Scleroderma, Claudio Lunardi, Rajan Madhok (23535), Group ", Voskuyl, A.E., Worthington, Jane, Egurbide, M.V., Jörg H W Distler, Saez-Comet, L., Callejas-Rubio, José Luis, Voskuyl, Alexandre E, van Laar JM, Simeón, Carmen P., Gabriela Riemekasten (276243), Denton, Christopher, Schuerwegh Annemie J., Camps MT, Paolo Airó (5650819), Witte T, Carmona, Francisco David, Denton, C., Lunardi, C., Fernández-Castro Mónica, Simeón, Carmen P, Riemekasten G, Luis Sáez-Comet (276239), Fonseca Carmen, Fernández-Castro, M., Herrick, Ariane, Timothy R D J Radstake, Scorza, R., Madhok, R., Denton Christopher, Fonseca, Carmen, Beretta L, Christopher Denton, Luis Sá Ez-Comet, Worthington, J., José Luis Callejas, Beretta, L., Annemie J Schuerwegh, Kreuter Alexander, Simeón CP, Nicolas Hunzelmann (213980), Lunardi Claudio, Jane Worthington (23502), Torsten Witte (32240), Emma Beltrán (276240), Lunardi, Claudio, Shiels, P., Carreira Patricia E., Fonseca C, Sáez Comet L, Shiels, Paul, Martín, J., Carmen Fonseca, F. David Carmona (276235), Riemekasten, G., Witte, T., Luis Sáez-Comet, Radstake, Timothy R. D. J., Jö Rg, van Laar, Jacob M., Egurbide María Victoria, Fernández-Castro, Monica, Radstake, T.R.D.J., van Laar Jacob M., Ariane Herrick, Emma Beltrán, Christopher Denton (276245), Alexander Kreuter, Martín Javier, Mó Nica Ferná Ndez-Castro, Shiels P, Vonk, Madelon C, Carreira, Patricia E, Fonseca, C., Paul Shiels, Callejas José Luis, Carmen P Simeó N, Martin JE, Lorenzo Beretta (214056), Egurbide MV, Distler Jörg H. W., Raffaella Scorza (214013), Vonk, Madelon C., María Victoria Egurbide, Hunzelmann, Nicolas, Carmona, F. David, Schuerwegh, Annemie J., Jose-Ezequiel Martin, Beretta Lorenzo, Patricia E Carreira, María Teresa Camps (276241), Scorza Raffaella, Annemie J. Schuerwegh (213966), Sáez-Comet Luis, F David Carmona, María Victoria Egurbide (276242), Laar, J.M. van, Hunzelmann, N., Worthington Jane, Martin, Jose-Ezequiel, van Laar, Jacob M, Spanish Scleroderma Group, Jose-Ezequiel Martin (213926), Distler JH, Radstake, Timothy R D J, Distler, Jörg H. W., Camps, Teresa   +217 more
core   +1 more source

Study of early atherosclerosis in juvenile-onset systemic lupus erythematosus patients

Egyptian Rheumatology and Rehabilitation, 2017
Objective The aim of this study was to investigate early atherosclerotic changes in juvenile-onset systemic lupus erythematosus (jSLE) patients and its relation with disease activity.
Emtethal A Said Ahmed, Sahar S Ganeb, Ahmed Y El-shambaky, Osama T Galal, Mai Y Tohamy   +4 more
doaj   +1 more source

Expert Perspectives: Toward Treat‐to‐Target Management in Adult Idiopathic Inflammatory Myopathies

Arthritis &Rheumatology, EarlyView.
Treat‐to‐target has transformed the management of several rheumatic diseases through predefined therapeutic goals, structured disease assessment, and timely treatment adjustment. Despite major advances in the understanding and treatment of idiopathic inflammatory myopathies (IIM), a formal treat‐to‐target framework for adult IIM has not yet been ...
Shiri Keret, Nantakarn Pongtarakulpanit, Rohit Aggarwal   +2 more
wiley   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Prevalence of pregnancy and birth outcomes following biologic exposure in immune‐mediated inflammatory diseases: A population‐based study

British Journal of Clinical Pharmacology, EarlyView.
Aims Almost 5% of pregnancies are affected by immune‐mediated inflammatory diseases (IMIDs). As treatments become available, understanding their use during pregnancy is important. We aimed to describe maternal, pregnancy and infant outcomes among IMID pregnancies exposed to biologic therapies. Methods Using the Merative™ MarketScan® Commercial Database,
Leah K. Flatman, Lisiane F. Leal, Gabra Nohmie, Anick Bérard   +3 more
wiley   +1 more source

Systemic lupus erythematosus with juvenile onset: current status of the problem (literature review)

Современная ревматология
Patients with juvenile-onset systemic lupus erythematosus (jSLE) account for up to 25% of all SLE patients. The main difference between jSLE and SLE in adults is the greater role of genetic factors in the pathogenesis, higher activity, earlier ...
M. I. Kaleda, I.  P. Nikishina
doaj   +1 more source

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

Ibrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen, Ningning Zhang, Ruirui Zhang, Lan Zhang, Dadong Luo, Junqiang Li, Yaqing Liu, Yunan Wang, Xinyue Duan, Xin Tian, Tiancheng Wang   +10 more
wiley   +1 more source

AB0481 Vitamin D Levels in Children, Adolescents, and Young Adults with Juvenile Onset Systemic Lupus Erythematosus: A Transversal Study

, 2014
Vitamin D Levels in Children, Adolescents, and Young Adults with Juvenile Onset Systemic Lupus Erythematosus: A Transversal ...
Lepri, Gemma, Matucci Cerinic, Marco, Stagi, Stefano, Cavalli, Loredana, Brandi, Maria Luisa, Bertini, Federico, Falcini, Fernanda   +6 more
core   +1 more source

Nail Disorders in Systemic Conditions

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail findings in children can be indicative of an underlying systemic disease. Many of these findings are seen in multiple entities and are not specific to one disease. The importance of specifically examining for these nail changes cannot be overstated.
Jane Sanders Bellet
wiley   +1 more source