Results 81 to 90 of about 1,882,441 (191)

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

Periodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer, Luigi Nibali, Noha Zoheir, Niki M. Moutsopoulos, Bruno G. Loos   +4 more
wiley   +1 more source

Revisiting Childhood-Onset Systemic Lupus Erythematosus

Childhood-onset systemic lupus erythematosus (cSLE) is a chronic autoimmune disease with a multisystemic involvement diagnosed during childhood. The disease is marked by the production of autoantibodies targeting self-antigens, often before symptoms ...
Pınar Özge Avar-Aydın, Hermine I. Brunner   +1 more
core   +1 more source

Hepatitis A virus vaccination in childhood-onset systemic lupus erythematosus

, 2019
Objectives: Vaccination of systemic lupus erythematosus patients with non-live vaccines may decrease vaccine-preventable infections and mortalities.
Adrovic, A., Barut, K., Kasapcopur, O., Yuksel, P., Sahin, S., Kocazeybek, B. S., Sazak, S., Mertoglu, S., Beser, O. F.   +8 more
core   +1 more source

Belimumab in the treatment of systemic lupus erythematosus with juvenile onset: Results of a single-center retrospective study

Научно-практическая ревматология
The treatment of systemic lupus erythematosus with juvenile onset (jSLE) remains a difficult task, taking into account the more aggressive course of the disease, requiring the appointment of various therapy regimens, including mainly a combination of ...
Maria I. Kaleda, Irina P. Nikishina, Tamari N. Pachkoria, Anna N. Shapovalenko   +3 more
doaj   +1 more source

Pathophysiology of the gut–eye axis in a Sjögren's disease‐like dry eye mouse model: An exploratory evaluation of dietary heat‐treated Enterococcus faecalis FK‐23

Experimental Physiology, EarlyView.
Abstract Sjögren's disease is an autoimmune disease characterized by severe dry eye, but its pathophysiology remains unclear. Non‐obese diabetic (NOD) mice develop Sjögren's disease‐like dry eye prior to the onset of diabetes. Although intestinal immune abnormalities precede diabetes in NOD mice, their relationship to dry eye remains poorly understood.
Kenji Goto, Shigekazu Takemura, Yukiko Minamiyama, Toshikazu Yoshikawa   +3 more
wiley   +1 more source

Acute Acalculous Cholecystitis In Juvenile Systemic Lupus Erythematosus

, 2015
Small- and medium-vessel vasculitis is a common manifestation in systemic lupus erythematosus (SLE) and may occur in any organ. However, acute acalculous cholecystitis is a rare abdominal manifestation in SLE, especially in children.
Appenzeller S., Mendonca J.A., Marques-Neto J.F., Prando P.   +3 more
core   +1 more source

Rheumatologic Manifestations of Patients With Type B Insulin Resistance

Arthritis Care &Research, Volume 78, Issue 9, Page 1195-1200, September 2026.
Objective The objectives of this study were to identify laboratory and clinical features associated with type B insulin resistance (TBIR), a rare condition caused by autoantibodies that inhibit the insulin receptor, most frequently occurring in the setting of systemic lupus erythematosus (SLE), and to increase awareness of this rare, life‐threatening ...
S. Amara Ogbonnaya, Sandra G. Williams, Raphael A. Kirou, Marissa Lightbourne, Rebecca J. Brown   +4 more
wiley   +1 more source

Lupus Enteritis: An Unusual Manifestation of Systemic Lupus Erythematosus

, 2023
Though gastrointestinal symptoms are common in Systemic Lupus Erythematosus (SLE), lupus enteritis remains a rare manifestation of the disease. The clinical picture may be non-specific but should be considered in patients with abdominal pain, as this ...
Dr. Amitra Ramrattan
core  

NEUROPSYCHIATRIC DISORDERS IN JUVENILE-ONSET SYSTEMIC LUPUS ERYTHEMATOSUS: RESULTS FROM A RETROSPECTIVE STUDY

Научно-практическая ревматология, 2020
Objective: to analyze clinical features and immunological abnormalities in juvenile-onset systemic lupus erythematosus (SLE) with neurolupus and to compare findings with the data available in the literature.Subjects and methods.
M. I. Kaleda, I. P. Nikishina, S. I. Glukhova, N. Yu. Stepanenko   +3 more
doaj   +1 more source

A Multifaceted Interplay Among Hemophagocytosis, Interleukin‐18, and Type I Interferon Distinguishes Still Disease From Other Autoinflammatory Diseases

Arthritis &Rheumatology, Volume 78, Issue 9, Page 1961-1974, September 2026.
Objective The unknown pathophysiology and the lack of specific features for systemic juvenile idiopathic arthritis and adult‐onset Still disease (collectively known as Still disease; SD) delay diagnosis and appropriate treatment. The goal of this study was to identify features and mechanisms that distinguish SD from other systemic autoinflammatory ...
Yvonne M. Mueller, Charlotte Girard, Harmen J. G. van de Werken, Stefan J. Erkeland, Dwin G. B. Grashof, Laurie Vaillant, Renske J. H. den Dekker, Iris van Zuijen, Sharon Veenbergen, Fanny Coffin, Eric Bindels, Yvan Jamilloux, Katerina Laskari, Vassili Soumelis, Bruno Fautrel, Cem Gabay, Peter D. Katsikis   +16 more
wiley   +1 more source