Results 101 to 110 of about 1,882,441 (191)

Mapping the Altered Landscape of TCR Repertoire in Autoimmune Diseases

Immunological Reviews, Volume 342, Issue 1, September 2026.
ABSTRACT Autoimmune diseases arise from the breakdown of immune tolerance through complex interactions between genetic predisposition, environmental exposures, and adaptive immune responses. High‐throughput T‐cell receptor (TCR) repertoire sequencing has transformed our ability to characterize these responses, providing unprecedented insights into ...
Celine Albalaa, Martin Pezous, David Klatzmann, Encarnita Mariotti‐Ferrandiz   +3 more
wiley   +1 more source

Clinical Features, Management, and Outcomes of Neuropsychiatric Lupus in Saudi Children, a Multicentric Study

Annals of Rheumatology and Autoimmunity
Introduction: Systemic lupus erythematosus (SLE) is a complex autoimmune disorder that affects several systems, including the neurological system. At some time over the course of their illness, around one-third of all children with SLE will exhibit ...
Mohammed Nashawi, Rahaf Shigdar, Hashim Shigdar, Reima Bakry, Abdulaziz Almutairi, Faris Althubaiti, Lujain Akbar, Emtenan Basahl   +7 more
doaj   +1 more source

Comparison of estimates of body fat content in childhood-onset systemic lupus erythematosus

, 2017
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)We aimed to compare estimates of body fat content with respect to their ability to predict the percentage of body fat, confirmed by dual-energy X-ray absorptiometry scans in childhood ...
Peres, F. A., Ramos, C. D., Santos, A. de Oliveira, Appenzeller, S., Sinicato, N. A., Pelicari, K. de Oliveira, Marini, R.   +6 more
core   +1 more source

Problems of systemic connective tissue diseases of childhood in historical perspective

Научно-практическая ревматология
The relevance of study systemic connective tissue diseases with juvenile onset for modern medicine is determined by the trend towards their growth in the population, the difficulty of early diagnosis, the rapid development of disability and a poor life ...
M. I. Kaleda, I. P. Nikishina
doaj   +1 more source

Geographical Clustering of Juvenile Onset Systemic Lupus Erythematosus within the Sultanate of Oman

Oman Medical Journal, 2013
Objective: While SLE is found worldwide, there is diversity in clinical presentation of the disease according to geographical variations. The aim of this study is to describe geographical distributions of childhood onset SLE within Oman to identify ...
Ibrahim Al-Zakwani, Sharef Waadallah Sharef, Safiya Al-Abrawi, Reem Abdwani   +3 more
doaj   +1 more source

Kawasaki disease and juvenile systemic lupus erythematosus

, 2012
Kawasaki disease (KD) is a common vasculitis in childhood. To the authors' knowledge, only one case of juvenile systemic lupus erythematosus (JSLE)-like onset mimicking KD and another case of KD and JSLE association have previously been described ...
Almeida, R. T., Sakane, P. T., Sallum, A. M. E., Aikawa, N. E., Diniz, J. C., Silva, C. A.   +5 more
core   +1 more source

Tapasin gene polymorphism in systemic onset juvenile rheumatoid arthritis: a family-based case-control study [PDF]

, 2005
Juvenile rheumatoid arthritis (JRA) comprises a group of chronic systemic inflammatory disorders that primarily affect joints and can cause long-term disability.
Woo, P, Colbert, RA, Bukulmez, H, Thompson, SD, Twine, NA, Tsoras, M, Glass, DN, Olson, JM, Fife, M, Elston, RC   +9 more
core  

Cutaneous manifestations of juvenile onset lupus erythematosus: A clinical study

Indian Journal of Paediatric Dermatology, 2018
Introduction: Juvenile-onset systemic lupus erythematosus (SLE) is one of the most common systemic autoimmune connective tissue disorders in children.
Vinitha Panicker, Anil Mathew, Gopikrishnan Anjaneyan, Soumya Jagadeesan, S. Lekshmi, Jacob Thomas   +5 more
doaj   +1 more source

Cytokines in relation to autoantibodies before onset of symptoms for systemic lupus erythematosus

, 2014
Objectives: A number of cytokines and chemokines were analysed and related to autoantibodies in blood samples pre-dating the onset of symptoms of systemic lupus erythematosus.
Eriksson, Catharina,, Rantapää Dahlqvist, Solbritt,   +1 more
core   +1 more source

Arginine mutation alters binding of a human monoclonal antibody to antigens linked to systemic lupus erythematosus and the antiphospholipid syndrome [PDF]

, 2007
Objective: Previous studies have shown the importance of somatic mutations and arginine residues in the complementarity-determining regions (CDRs) of pathogenic anti-double-stranded DNA (anti-dsDNA) antibodies in human and murine lupus, and in studies of
Yiannis Ioannou, Lambrianides, A., Anisur Rahman, Isenberg, D.A., Lesley Mason, Giles, I., Ioannou, Y., Latchman, D.S., Mason, L., Jessica J. Manson, Ian Giles, Manson, J.J., David A. Isenberg, David S. Latchman, Rahman, A., Anastasia Lambrianides   +15 more
core   +1 more source