Results 31 to 40 of about 1,882,441 (191)

Lack of the long pentraxin PTX3 promotes autoimmune lung disease but not glomerulonephritis in murine systemic lupus erythematosus. [PDF]

open access: yes, 2011
The long pentraxin PTX3 has multiple roles in innate immunity. For example, PTX3 regulates C1q binding to pathogens and dead cells and regulates their uptake by phagocytes. It also inhibits P-selectin-mediated recruitment of leukocytes.
Mantovani Alberto   +32 more
core   +1 more source

Disease characteristics in patients with juvenile- and adult-onset systemic lupus erythematosus: A multi-center comparative study

open access: yesThe Turkish Journal of Gastroenterology, 2022
Objectives: This study aims to compare disease characteristics in patients with juvenile-onset systemic lupus erythematosus (JSLE) and adult-onset systemic lupus erythematosus (ASLE). Patients and methods: Between June 2010 and March 2020, a total of
Sherif M Gamal   +4 more
doaj  

Autoantibodies against complement C1q in systemic lupus erythemathosus [PDF]

open access: yes, 2008
Complement and C1q, the first component of the classical pathway of activation of the complement system, are considered to be involved in the pathogenesis of systemic lupus erythematosus (SLE), a systemic autoimmune disease.
Bigler, Cornelia
core   +1 more source

Belimumab : a technological advance for systemic lupus erythematosus patients? Report of a systematic review and meta-analysis [PDF]

open access: yes, 2013
Objectives: To undertake a systematic review and meta-analysis to investigate clinical effectiveness of belimumab for patients with systemic lupus erythematosus (SLE) and antinuclear and/or anti-double-stranded DNA (dsDNA) autoantibodies.
Hartley, Louise   +17 more
core   +1 more source

Oral Ulcers in Juvenile-Onset Systemic Lupus Erythematosus: A Review of the Literature. [PDF]

open access: yesAm J Clin Dermatol, 2017
Oral ulcers are the most common mucosal sign in juvenile-onset systemic lupus erythematosus (JSLE). The ulcers are one of the key clinical features; however, the terminology of oral ulcers, especially in JSLE patients, is often vague and ill-defined. In fact, there are several clinical manifestations of oral ulcers in JSLE, and some lesions occur when ...
Rodsaward P   +5 more
europepmc   +4 more sources

Phototesting and photoprotection in LE [PDF]

open access: yes, 1997
Photosensitivity and induction of skin lesions following UV radiation is a common problem of patients with cutaneous and systemic forms of lupus erythematosus.
Kind, P., Walchner, M., Messer, G.
core   +1 more source

Mucocutaneous manifestations in juvenile-onset systemic lupus erythematosus: a review of literature [PDF]

open access: yesPediatric Rheumatology, 2015
Patients diagnosed with juvenile-onset systemic lupus erythematosus (JSLE) often have skin and oral lesions as part of their presentation. These mucocutaneous lesions, as defined by the American College of Rheumatology (ACR) in 1997, include malar rash, discoid rash, photosensitivity and oral ulcers. It is therefore essential to recognize mucocutaneous
Chiewchengchol, Direkrit   +3 more
openaire   +2 more sources

The systemic lupus erythematosus IRF5 risk haplotype is associated with systemic sclerosis [PDF]

open access: yes, 2013
Systemic sclerosis (SSc) is a fibrotic autoimmune disease in which the genetic component plays an important role. One of the strongest SSc association signals outside the human leukocyte antigen (HLA) region corresponds to interferon (IFN) regulatory ...
Schuerwegh, A. J.   +219 more
core   +2 more sources

The Swiss Systemic lupus erythematosus Cohort Study (SSCS) - cross-sectional analysis of clinical characteristics and treatments across different medical disciplines in Switzerland [PDF]

open access: yes, 2014
OBJECTIVES: To describe disease characteristics and treatment modalities in a multidisciplinary cohort of systemic lupus erythematosus (SLE) patients in Switzerland.
Stoll, T.   +48 more
core   +1 more source

Juvenile and juvenile-onset systemic lupus erythematosus patients: Clinical characteristics, disease activity and damage

open access: yesEgyptian Pediatric Association Gazette, 2017
Background: The diagnosis of systemic lupus erythematosus (SLE) in children is challenging. The heterogeneous manifestations and disease impact on the child’s growth highlight the importance of timely diagnosis and management.
Rasha E. Gheith   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy