Results 31 to 40 of about 2,000,650 (198)
Demographic, clinical, and laboratory parameters of the juvenile-onset systemic lupus erythematosus patients.
Butsabong Lerkvaleekul (12055191) +5 more
core +1 more source
The role of the host—Neutrophil biology
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Lack of the long pentraxin PTX3 promotes autoimmune lung disease but not glomerulonephritis in murine systemic lupus erythematosus. [PDF]
The long pentraxin PTX3 has multiple roles in innate immunity. For example, PTX3 regulates C1q binding to pathogens and dead cells and regulates their uptake by phagocytes. It also inhibits P-selectin-mediated recruitment of leukocytes.
Mantovani Alberto +32 more
core +1 more source
Genetic and epigenetic factors shape phenotypes and outcomes in systemic lupus erythematosus - focus on juvenile-onset systemic lupus erythematosus. [PDF]
Purpose of review Systemic lupus erythematosus (SLE) is a severe autoimmune/inflammatory disease. Patients with juvenile disease-onset and those of non-European ancestry are most severely affected. While the exact pathophysiology remains unknown, common and rare gene variants in the context of environmental exposure and ...
Charras A +3 more
europepmc +3 more sources
Objectives: This study aims to compare disease characteristics in patients with juvenile-onset systemic lupus erythematosus (JSLE) and adult-onset systemic lupus erythematosus (ASLE). Patients and methods: Between June 2010 and March 2020, a total of
Sherif M Gamal +4 more
doaj
Stratification of the juvenile-onset systemic lupus erythematosus patients by the median percentage of each lymphocyte subset.
Butsabong Lerkvaleekul (12055191) +5 more
core +1 more source
Serum calcification propensity is independently associated with disease activity in systemic lupus erythematosus. [PDF]
Systemic lupus erythematosus (SLE) is associated with severe cardiovascular complications. The T50 score is a novel functional blood test quantifying calcification propensity in serum.
Chizzolini, Carlo +50 more
core +3 more sources
Mucocutaneous manifestations in juvenile-onset systemic lupus erythematosus: a review of literature [PDF]
Patients diagnosed with juvenile-onset systemic lupus erythematosus (JSLE) often have skin and oral lesions as part of their presentation. These mucocutaneous lesions, as defined by the American College of Rheumatology (ACR) in 1997, include malar rash, discoid rash, photosensitivity and oral ulcers. It is therefore essential to recognize mucocutaneous
Chiewchengchol, Direkrit +3 more
openaire +2 more sources
Oral Ulcers in Juvenile-Onset Systemic Lupus Erythematosus: A Review of the Literature. [PDF]
Oral ulcers are the most common mucosal sign in juvenile-onset systemic lupus erythematosus (JSLE). The ulcers are one of the key clinical features; however, the terminology of oral ulcers, especially in JSLE patients, is often vague and ill-defined. In fact, there are several clinical manifestations of oral ulcers in JSLE, and some lesions occur when ...
Rodsaward P +5 more
europepmc +4 more sources
Phototesting and photoprotection in LE [PDF]
Photosensitivity and induction of skin lesions following UV radiation is a common problem of patients with cutaneous and systemic forms of lupus erythematosus.
Kind, P., Walchner, M., Messer, G.
core +1 more source

