Results 71 to 80 of about 67,974,619 (226)

AB0481 Vitamin D Levels in Children, Adolescents, and Young Adults with Juvenile Onset Systemic Lupus Erythematosus: A Transversal Study

, 2014
Vitamin D Levels in Children, Adolescents, and Young Adults with Juvenile Onset Systemic Lupus Erythematosus: A Transversal ...
Lepri, Gemma, Matucci Cerinic, Marco, Stagi, Stefano, Cavalli, Loredana, Brandi, Maria Luisa, Bertini, Federico, Falcini, Fernanda   +6 more
core   +1 more source

Prevalence of pregnancy and birth outcomes following biologic exposure in immune‐mediated inflammatory diseases: A population‐based study

British Journal of Clinical Pharmacology, EarlyView.
Aims Almost 5% of pregnancies are affected by immune‐mediated inflammatory diseases (IMIDs). As treatments become available, understanding their use during pregnancy is important. We aimed to describe maternal, pregnancy and infant outcomes among IMID pregnancies exposed to biologic therapies. Methods Using the Merative™ MarketScan® Commercial Database,
Leah K. Flatman, Lisiane F. Leal, Gabra Nohmie, Anick Bérard   +3 more
wiley   +1 more source

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

Ibrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen, Ningning Zhang, Ruirui Zhang, Lan Zhang, Dadong Luo, Junqiang Li, Yaqing Liu, Yunan Wang, Xinyue Duan, Xin Tian, Tiancheng Wang   +10 more
wiley   +1 more source

Ambulatory blood pressure and subclinical cardiovascular disease in patients with juvenile-onset systemic lupus erythematosus

, 2013
The aim of this study was to evaluate the presence of subclinical cardiovascular disease (CVD) and its relation to risk factors, particularly hypertension in juvenile-onset systemic lupus erythematosus (SLE)
Arisoy, Nil, Kasapcopur, Ozgur, Gokalp, Selman, Tasdemir, Mehmet, Canpolat, Nur, Sever, Lale, Bor, Meltem, Caliskan, Salim   +7 more
core   +1 more source

The V_H gene repertoire of splenic B cells and somatic hypermutation in systemic lupus erythematosus [PDF]

, 2003
In systemic lupus erythematosus (SLE) it has been hypothesized that self-reactive B cells arise from virgin B cells that express low-affinity, nonpathogenic germline V genes that are cross-reactive for self and microbial antigens, which convert to high ...
Stott, DI, Gary Rowley, Fraser, N.L.W., Field, M, Fraser, NLW, Rowley, G., Field, M., Max Field, Rowley, G, David I Stott, Stott, D.I., Nicola LW Fraser   +11 more
core   +1 more source

Autoantibody-based subgroups and longitudinal seroconversion in juvenile-onset systemic lupus erythematosus

Lupus Science & Medicine, 2023
Objective To explore the clinical value of autoantibody-based subgroup framework and the trend of autoantibody fluctuation in juvenile-onset SLE (JSLE). Methods Eighty-seven patients with JSLE were retrospectively collected and divided into ...
Shengfang Bao, Hua Huang, Yingying Jin, Fei Ding, Zhen Yang, Xuemei Xu, Chenxi Liu, Jingyi Lu, Yanliang Jin   +8 more
openaire   +3 more sources

Cutaneous manifestations of juvenile onset lupus erythematosus: A clinical study

Indian Journal of Paediatric Dermatology, 2018
Introduction: Juvenile-onset systemic lupus erythematosus (SLE) is one of the most common systemic autoimmune connective tissue disorders in children.
Vinitha Panicker, Anil Mathew, Gopikrishnan Anjaneyan, Soumya Jagadeesan, S. Lekshmi, Jacob Thomas   +5 more
doaj   +1 more source

Associations of lymphocyte subpopulations with clinical phenotypes and long-term outcomes in juvenile-onset systemic lupus erythematosus.

PLoS ONE, 2022
ObjectiveJuvenile-onset systemic lupus erythematosus (JSLE) is a complex and heterogeneous immune-mediated disease. Cellular components have crucial roles in disease phenotypes and outcomes.
Butsabong Lerkvaleekul, Nopporn Apiwattanakul, Kanchana Tangnararatchakit, Nisa Jirapattananon, Supanart Srisala, Soamarat Vilaiyuk   +5 more
doaj   +1 more source

Neuropsychiatric lupus in Malaysian children: clinical characteristics, imaging features and 12-month outcomes

The Turkish Journal of Pediatrics, 2021
Background. Neuropsychiatric lupus (NPSLE) serves as a marker of severe disease in children with juvenile onset systemic lupus erythematosus (JSLE). This study aims to characterise the clinical and imaging features at diagnosis; and outcomes after
Sern Chin Lim, Yusma Lyana Md-Yusof, Bushra Johari, Roqiah Fatmawati Abdul-Kadir, Swee Ping Tang   +4 more
doaj   +1 more source

Nail Disorders in Systemic Conditions

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail findings in children can be indicative of an underlying systemic disease. Many of these findings are seen in multiple entities and are not specific to one disease. The importance of specifically examining for these nail changes cannot be overstated.
Jane Sanders Bellet
wiley   +1 more source