Results 61 to 70 of about 656,324 (263)
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
, 2020 18 páginasWithin sustainable transportation systems, the adoption of electric vehicles (EVs) is considered as a potential solution to problems such as energy security, climate change, urban-air quality, and public health.
Sarmiento, Alfonso T. +2 more
core +1 more source
Practical use of ‘Diprifusor’ systems [PDF]
Anaesthesia, 1998 This paper describes practical aspects relating to the safe use of target controlled infusion systems in anaesthesia. Consideration is given to the correct use of syringes and infusion lines for any target controlled infusion system. The importance of appropriate connections, minimising infusion line dead space and the avoidance of syphoning are ...
openaire +2 more sources
FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
A Sketch of a System of Theory and Practice [PDF]
Political Studies Review, 2015 Most political theorists are committed to one particular view about the relation between theory and practice. It is argued in this article that there are in fact four possible ways of relating theory and practice, which are distinguished in terms of the answers that are given to two distinct questions.
openaire +3 more sources
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Developing a systemic textual analysis method based on the human activity system modelling language of soft system methodology (SSM) [PDF]
, 2006 The paper introduces a textual analysis method which utilises a modified version of the Human Activity System (HAS) modelling language from Soft Systems Methodology (SSM).
Hindle, G
core
A systemic framework to develop sustainable engineering solutions in rural communities in Colombia
, 2011 En varias zonas rurales de Colombia hay una grave falta de suministro de calidad del agua. Por lo tanto, la situación problemática se entiende como una compleja que involucra a partes interesadas con intereses pluralistas, múltiples variables y requiere ...
Torres, Camilo +11 more
core +1 more source