Results 81 to 90 of about 656,324 (263)
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
A qualitative study of systemic leadership training in a Danish municipality. Leaders’ experiences of participating in leadership training based on a systemic approach [PDF]
, 2020 DeRue (2011) finds that the literature on leadership emphasizes dominant discourses in which the personality characteristics, ability and leadership behaviour of the individual leader are central because these are important influences on employees ...
Hofsmarken, Terje
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Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Systemic Evaluation Methodology for Technology Supported Learning [PDF]
, 2010 Developments in information and communication technologies have opened up new possibilities for organising and supporting learning activity. Appropriate evaluation methodology is required to help practitioners understand how and why their implemented ...
Hart, Diane
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Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
On the Practicality of Abstract Equation Systems [PDF]
, 1995 Mulkers, Anne +3 more
openaire +3 more sources
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Karl Tomm's approach to systemic practice
, 2014 Karl Tomm occupies a pivotal position in the evolution of systemic family therapy. He played an important role in bringing the work of the original Milan systemic family therapy team to the attention of family therapists in North America, the UK and ...
Carr, Alan
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Designing for the Systemic Proximity: Positioning and Placemaking [PDF]
The workshop explores and strategically uses the concept of Systemic Proximity, focusing on how participants can effectively position themselves as designers, researchers and placemakers.
Sedini, Carla +2 more
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