Results 71 to 80 of about 28,355 (295)

Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery

Advanced Science, EarlyView.
Systematic engineering of hydrophobic tail architecture in vitamin B5‐derived ionizable lipids establishes a comprehensive structure–activity relationship framework for mRNA delivery. Combined lipidtail and formulation optimization identifies TM1‐OPT3‐C, a lipid nanoparticle platform that improves efficacy–safety balance through efficient mRNA delivery,
Seo‐Hyeon Bae, Jisun Lee, Jae‐Hun Ahn, Hosam Choi, Huijeong Choi, Jungmin Kim, Minho Kang, Ho Rim Oh, So Hyun Park, Eun Young Oh, Sanghyuk Jeon, Yeeun Lee, Yu‐Sun Lee, Na‐Young Lee, Hee‐Jin Bae, Jina Kwak, Jooil Kim, Nakyung Lee, Beomsun Kang, Ji‐Hye Kim, Eunsaem Song, Daesub Song, Hyunho Yoon, Sang‐Myeong Lee, Hyewon Youn, Kiyoun Lee, Byeong‐Cheol Kang, Jae‐Hwan Nam   +27 more
wiley   +1 more source

Anti-Black racism in library and information science curriculum

Partnership: The Canadian Journal of Library and Information Practice and Research
Canadian communities are facing a crisis of inequity, and library service providers must do more to respond to the causal conditions of anti-Black and other forms of systemic racism (Black & Mehra, 2023). Beginning in 2022, the first known Canadian MLIS
Amber Matthews
doaj   +1 more source

Engineering a 660 nm‐Responsive Optogenetic Inducer of Pyroptosis for Precision Cancer Therapy

Advanced Science, EarlyView.
This study reports a bioorthogonal pyroptosis inducer, PyroRACS. By using a red‐light‐responsive Cre‐On genetic switch to control the expression of highly cytotoxic GSDMDNT, PyroRACS enables the artificial induction of pyroptosis with precise spatiotemporal control.
Mengkai Zhang, Zhichao Li, Yonghao Ma, Yangyang Sun, Wei Chen, Weiren Huang   +5 more
wiley   +1 more source

The rain feels different under the same umbrella: Experiences with poverty across LGBTQ subgroups

American Journal of Community Psychology, EarlyView.
Abstract Population‐based survey data have demonstrated that LGBTQ communities report varying rates of economic insecurity, yet very little research directly assesses how pathways into and experiences with poverty look different among subgroups at the intersections of sexual orientation and gender identity (SOGI).
Bianca D. M. Wilson, Lillian Nguyen
wiley   +1 more source

The psychosocial toll of Dublin III on asylum seekers in the Netherlands

American Journal of Community Psychology, EarlyView.
Abstract The Dublin III Regulation determines which EU Member State is responsible for examining asylum claims, but its implementation carries significant consequences for those subjected to it. This study examines how Dublin III, as implemented in the Netherlands, affects asylum seekers' psychosocial wellbeing using Silove′s Adaptation and Development
Imen El Amouri
wiley   +1 more source

Dissecting systemic racism: policies, practices and epistemologies creating racialized systems of care for Indigenous peoples

International Journal for Equity in Health, 2021
In this paper we explore some of the ways systemic racism operates and is maintained within our health and social services. We look at a very specific context, that of Nunavik Quebec, land and home to 13,000 Nunavimmiut, citizens of Quebec and Canada ...
Sarah Louise Fraser, Dominique Gaulin, William Daibhid Fraser   +2 more
doaj   +1 more source

Systemic Racism Curriculum Project: Site Mapping [PDF]

, 2018
Since spring 2017, I have been involved with a group of researchers on the Systemic Racism Curriculum Project. The goal of the group and research is to find effective means of educating people, specifically white people about the realities of systemic ...
Ferris, Matthew
core   +1 more source

The Evaluation of Systemic Racism and its Present-Day Integration in Society [PDF]

, 2021
Rinku Sen, executive director of Race Forward, defines systemic racism, which is also known as institutional racism, as a form of racism that is embedded as the normal practice within society or standard operating procedures within an organization.
Inglis, Natoya
core  

Using photovoice to understand community perceptions of firearm risks and protective factors among Asian Americans

American Journal of Community Psychology, EarlyView.
Abstract This study used photovoice methodology to explore Asian Americans' perspectives on the root causes and protective factors of firearm violence in their communities. Photovoice provided a participatory platform for community members to document lived experiences and identify priorities for change.
Tsu‐Yin Wu, Szu‐Hsien Chen, Xining Yang, Ken Resnicow, Hsing‐Fang Hsieh   +4 more
wiley   +1 more source

¿No Hay Racismo?: application of the levels of racism framework to Latinx perspectives on barriers to health and wellbeing

BMC Public Health
Background The purpose of this study is to increase understanding of the forms of systemic racism experienced by Latinx communities in North Carolina during the COVID-19 pandemic as identified by Latinx community health workers (CHWs) and community-based
Gabriela Plasencia, Kamaria Kaalund, Rohan Gupta, Viviana Martinez-Bianchi, Rosa Gonzalez-Guarda, Jessica Sperling, Andrea Thoumi   +6 more
doaj   +1 more source