Results 41 to 50 of about 713,056 (265)
Beneficial Microorganisms as a Sustainable Alternative for Mitigating Biotic Stresses in Crops
Stresses, 2023 Nowadays, population growth, the global temperature increase, and the appearance of emerging diseases in important crops generate uncertainty regarding world food security.
Ana María García-Montelongo +4 more
doaj +1 more source
Induced Systemic Resistance and the Rhizosphere Microbiome [PDF]
The Plant Pathology Journal, 2013 Microbial communities that are associated with plant roots are highly diverse and harbor tens of thousands of species. This so-called microbiome controls plant health through several mechanisms including the suppression of infectious diseases, which is especially prominent in disease suppressive soils.
Bakker +8 more
openaire +4 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Systems biology of diuretic resistance [PDF]
Journal of Clinical Investigation, 2015 Diuretics are commonly used to treat hypertension and extracellular fluid volume expansion. However, the development of compensatory responses in the kidney limits the benefit of this class of drugs. In this issue of the JCI, Grimm and colleagues use a systems biology approach in mice lacking the kinase SPAK and unravel a complex mechanism that ...
openaire +2 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
International Journal of Plant BiologyPhytophthora blight, caused by Phytophthora capsici, is a destructive disease that significantly constrains the production of chayote (Sechium edule) in Mexico, leading to substantial yield and economic losses. The increasing ineffectiveness of synthetic
José Rigoberto Arroyo-Axol +6 more
doaj +1 more source
Damage-Associated Molecular Pattern-Triggered Immunity in Plants
Frontiers in Plant Science, 2019 As a universal process in multicellular organisms, including animals and plants, cells usually emit danger signals when suffering from attacks of microbes and herbivores, or physical damage.
Shuguo Hou +3 more
doaj +1 more source
Antibiotic Resistance in Aquatic Systems
, 2017 Rivers, lakes and the ocean receive antibiotic resistance genes from human environments. The aquatic environments are a huge reservoir and exchange stage of antibiotic resistance genes.
Suzuki, Satoru +3 more
openaire +3 more sources
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source