Results 51 to 60 of about 3,283,184 (239)

Stem cell therapy for single ventricle congenital heart disease – current state and future directions

Advances in Interventional Cardiology, 2022
Hypoplastic left heart syndrome (HLHS) is one of the most complex forms of congenital heart disease, characterized by an underdeveloped left ventricle, outflow tract and aorta.
Agata Bilewska, Rachana Mishra, Artur Stefanowicz, Sudhish Sharma, Vivek Mehta, Sunjay Kaushal   +5 more
doaj   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Prognostic Value and Determinants of High-Sensitivity Cardiac Troponin T in Patients With a Systemic Right Ventricle: Insights From the SERVE Trial. [PDF]

J Am Heart Assoc
BACKGROUND The determinants and prognostic value of high-sensitivity cardiac troponin T (hs-cTnT) among patients with a systemic right ventricle are largely unknown. METHODS AND RESULTS Ninety-eight patients from the randomized controlled SERVE (
Ruperti-Repilado FJ, Tran F, Haaf P, Lopez-Ayala P, Greutmann M, Schwerzmann M, Bouchardy J, Gabriel H, Stambach D, Rutz T, Schwitter J, Wustmann K, Freese M, Mueller C, Tobler D.   +14 more
europepmc   +3 more sources

A Constraint‐Based Analytical Framework for Design‐Space Analysis and Material Screening of Tubular Multilayer Dielectric Elastomer Pumps for Extracorporeal Circulatory Applications

Advanced Materials Technologies, EarlyView.
A constraint‐based analytical framework maps the coupled effects of material properties, structural parameters, and operating conditions in tubular dielectric elastomer pumps for extracorporeal circulatory applications. The approach defines performance boundaries through mechanical, electrical, and hydraulic constraints and identifies feasible design ...
Yan Zhang, Amine Benouhiba, Yoan Civet, Yves Perriard   +3 more
wiley   +1 more source

Mechanisms of Acute Right Ventricular Injury in Cardiothoracic Surgical and Critical Care Settings: Part 2

, 2023
The right ventricle (RV) is intricately linked in the clinical presentation of critical illness; however, the basis of this is not well-understood and has not been studied as extensively as the left ventricle. There has been an increased awareness of the
Rosenberg A, Dimarakis I, Zochios V, Bangash MN, Shelley B, Khorsandi M, for Protecting the Right Ventricle Network (PRORVnet)., Valchanov K, Scott J, Akhtar W, Antonini M, Sato R, Yusuff H, Roscoe A, Dugar S, Chawla S   +15 more
core   +1 more source

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

Advanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang, Yu Dong, Yongsheng Du, Rui Gao, Lin Zhang, Fei Tong   +5 more
wiley   +1 more source

Isolated right superior vena cava draining into the left atrium in a child with vein of Galen aneurysmal malformation—case report

Journal of Cardiothoracic Surgery, 2018
Background Isolated right Superior Vena Cava drainage into the left atrium in the absence of other cardiac anomalies is an extremely rare condition. The vein of Galen aneurysmal malformation is a congenital vascular malformation.
Ahmed F. Elmahrouk, Abdelmonem Helal, Mohamed F. Ismail, Tamer Hamouda, Mohammed Mashali, Ahmed A. Jamjoom, Jameel A. Al-Ata   +6 more
doaj   +1 more source

Metastatic Ewing's sarcoma to the right ventricle [PDF]

, 2011
Ewing's sarcoma is a round cell neoplasm derived from neural crest cells that is part of the primitive neuroectodermal tumor (PNET) family. It is a rare, aggressive malignancy that affects young people, most commonly in the second decade of life.
Milliken, Jeffrey, Kirsh, M., Saremi, Farhood, Abolhoda, Amir, Sender, Leonard, Datrice, Nicole   +5 more
core  

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

Left-ventricle myocardium segmentation using a coupled level-set with a priori knowledge [PDF]

, 2006
This paper presents a coupled level-set segmentation of the myocardium of the left ventricle of the heart using a priori information. From a fast marching initialisation, two fronts representing the endocardium and epicardium boundaries of the left ...
Lynch, Michael, Ghita, Ovidiu, Whelan, Paul F.   +2 more
core   +2 more sources