Results 121 to 130 of about 1,292,257 (266)

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran   +13 more
wiley   +1 more source

The physics-based deterministic scenarios for earthquake hazards and losses of the Zhujiangkou fault in southern China

open access: yesnpj Natural Hazards
Dynamic rupture directivity significantly impacts earthquake hazard and loss assessments; yet, it is often overlooked, leading to uncertainties. We developed high-resolution, broadband, deterministic scenarios for earthquake hazards and losses of the ...
Yilong Li   +7 more
doaj   +1 more source

Systemic risk and the European Systemic Risk Board [PDF]

open access: yes, 2009
Financial crises are often characterised by a few financial institutions \ud failing, followed by a cascade of collapses. Economists are not good at \ud predicting which shocks will trigger an initial collapse. Thus, an early \ud warning system might be better focused on measuring systemic risk, or \ud the vulnerability of the financial system to the ...
openaire  

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller   +14 more
wiley   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird   +9 more
wiley   +1 more source

Spatiotemporal differentiation and dynamics simulation of China’s industrial soot and dust emissions

open access: yesScientific Reports
To address the challenge of balancing industrial development and environmental protection in China, we explore the spatiotemporal evolution characteristics, driving mechanisms, and emission reduction paths of industrial soot and dust emissions using an ...
Shouwei Li, Guoming Zhang
doaj   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe   +7 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Interaction of Intraprocedural Antiplatelets and Intravenous Thrombolysis in Acute Intracranial Stenting: RESISTANT Registry Subanalysis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes   +75 more
wiley   +1 more source

Tropical Cyclone Storm Surge‐Based Flood Risk Assessment Under Combined Scenarios of High Tides and Sea‐Level Rise: A Case Study of Hainan Island, China

open access: yesEarth's Future
In the context of climate change, coastal flood risk is intensifying globally, particularly in China, where intricate coastlines and frequent tropical cyclones make storm surges a major concern.
Ziying Zhou   +5 more
doaj   +1 more source

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