Results 101 to 110 of about 33,761 (217)

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Evaluating the performance of pixel-based and object-based multidimensional clustering algorithms for automated surface water mapping

Geo-spatial Information Science
Remote sensing observations of surface water are vital for effective water resource management and sustainable development. Unsupervised classification holds promise for automating large-scale surface water detection, and it helps solve the difficult ...
Bohao Li, Kai Liu, Ming Wang, Yanfang Wang, Linmei Zhuang, Weihua Zhu, Chenxia Li, Linhao Zhang, Yanan Chen   +8 more
doaj   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Analysis of pork price fluctuations during the special era when African swine fever and COVID-19 epidemic coexisted: an empirical study in Macau, China

Frontiers in Sustainable Food Systems
IntroductionEmergent crises can have a catastrophic impact on regional economic systems. The concurrent outbreaks of African Swine Fever (ASF) and the COVID-19 pandemic have severely affected Macau’s pork industry, making it an interesting case study for
Fang Xu, Fang Xu, Xiaoyong Ni, Xiaoyong Ni, Kai Liu, Kai Liu, Ming Wang, Ming Wang, Kangye Tan, Jun Hu, Jun Hu   +10 more
doaj   +1 more source

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

FEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court, Nigel Francis, Andrew Shore, Stephen Rutherford   +3 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

A systemic risk assessment methodological framework for the global polycrisis

Nature Communications
Human societies and ecological systems face increasingly severe risks, stemming from crossing planetary boundaries, worsening inequality, rising geo-political tensions, and new technologies.
Ajay Gambhir, Michael J. Albert, Sylvanus S. P. Doe, Jonathan F. Donges, Nadim Farajalla, Leandro L. Giatti, Haripriya Gundimeda, Sarah Hendel-Blackford, Thomas Homer-Dixon, Daniel Hoyer, Sumaya Adan, David Jacome-Polit, Luke Kemp, David Korowicz, Zora Kovacic, Jan Kwakkel, Laurie Laybourn, Robert Lempert, Ayan Mahamoud, Tom H. Oliver, Ivana E. Pavkova, Joseph Ponnoly, Vishwas Satgar, Megan Shipman, Jana Sillmann, Nick Silver, Samuel Stevenson, Ruth Richardson   +27 more
doaj   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han, Jiachun Pan, Yuehui Hong, Xiaoyuan Fan, Ming Yao, Lixin Zhou, Yicheng Zhu, Feng Feng, Jun Ni   +8 more
wiley   +1 more source