Results 91 to 100 of about 2,340,109 (293)

Dynamic changes in soil erosion and challenges to grain productivity in the black soil region of Northeast China

Ecological Indicators
Soil erosion presents a significant obstacle to food and ecosystem security. This study combined multi-source data to construct a soil erosion model and challenges to grain productivity in the black soil region of Northeast China.
Jiawang Zhang, Ming Wang, Kai Liu, Zhan’ao Zhao   +3 more
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Dynamic Earthquake-Induced Landslide Susceptibility Assessment Model: Integrating Machine Learning and Remote Sensing

Remote Sensing
Earthquake-induced landslides (EQILs) represent a serious secondary disaster of earthquakes, and conducting an effective assessment of earthquake-induced landslide susceptibility (ELSA) post-earthquake is helpful in reducing risk. In light of the diverse
Youtian Yang, Jidong Wu, Lili Wang, Ru Ya, Rumei Tang   +4 more
doaj   +1 more source

The impact of systemic risk on the diversification benefits of a risk portfolio [PDF]

, 2013
Risk diversification is the basis of insurance and investment. It is thus crucial to study the effects that could limit it. One of them is the existence of systemic risk that affects all the policies at the same time.
Busse, Marc, Dacorogna, Michel, Kratz, Marie   +2 more
core   +5 more sources

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Estimating Global Wheat Yields at 4 km Resolution during 1982–2020 by a Spatiotemporal Transferable Method

Remote Sensing
Reliable and spatially explicit information on global crop yield has paramount implications for food security and agricultural sustainability. However, most previous yield estimates are either coarse-resolution in both space and time or are based on ...
Zhao Zhang, Yuchuan Luo, Jichong Han, Jialu Xu, Fulu Tao   +4 more
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Divergent responses of forest canopy height to environmental conditions across China

Ecological Indicators
As major components of terrestrial ecosystems, forest ecosystems play an important role in sequestering carbon and hence mitigating climate change. Canopy height is a crucial factor characterizing the structure and function of forest ecosystems, yet the ...
Xiang Pan, Junjie Ji, Kailin Gao, Tao Wei, Mingzhu He, Xiaohan Zhang   +5 more
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Exposure of Global Rail and Road Infrastructures in Future Record‐Breaking Climate Extremes

Earth's Future
Transport infrastructures built on historical experience are expected to face multiple threats under climate change, especially the continuous interruptive losses and additional maintenance costs caused by more intense or frequent record‐breaking extreme
Qianzhi Wang, Kai Liu, Ming Wang, Elco Koks, Haizhong Wang   +4 more
doaj   +1 more source