Results 141 to 150 of about 1,628,316 (351)

Blocking CD248 molecules in perivascular stromal cells of patients with systemic sclerosis strongly inhibits their differentiation toward myofibroblasts and proliferation: A new potential target for antifibrotic therapy [PDF]

, 2018
Background: Fibrosis may be considered the hallmark of systemic sclerosis (SSc), the end stage triggered by different pathological events. Transforming growth factor-β (TGF-β) and platelet-derived growth factor BB (PDGF-BB) are profibrotic molecules ...
Berardicurti O., Carubbi F., Ciccia F., Cipriani P., Di Bartolomeo S., Di Benedetto P., Giacomelli R., Guggino G., Liakouli V., Panzera N., Ruscitti P., Triolo G.   +11 more
core   +1 more source

Lower-limb Ulcers in Systemic Sclerosis: A Multicentre Retrospective Case-control Study

Acta Dermato-Venereologica, 2018
Lower-limb ulcers in systemic sclerosis patients are rarely reported. The aim of this study was to describe the main causes and outcomes of lower-limb ulcers in systemic sclerosis patients and to assess factors associated with ischaemic causes (arterial ...
Gérôme Bohelay, Sophie Blaise, Pierre Levy, Antoine Claeys, Nathalie Baudot, Jean-Francois Cuny, Hervé Maillard, Florence Granel-Brocard, Thierry Boyé, Catherine Lok, Nathalie Bénéton, Camille Francès, Patricia Senet   +12 more
doaj   +1 more source

Interstitial lung disease associated with systemic sclerosis (SSc-ILD)

Respiratory Research, 2019
BackgroundSystemic sclerosis (SSc) is a rare connective tissue disease with a heterogeneous clinical course. Interstitial lung disease (ILD) is a common manifestation of SSc and a leading cause of death.Main bodyAll patients newly diagnosed with SSc ...
V. Cottin, K. Brown
semanticscholar   +1 more source

A Simple Manufactured Hardness Sensor Based on Multi‐Layer Liquid Metal Sensing for Surgical Robotics

Advanced Electronic Materials, EarlyView.
A continuous injection method fabricates a multi‐layer liquid metal sensor by laminating PDMS microfluidic layers, decoupling pressure, and deformation measurements. Its compact, thin design integrates into fingers or robotic digits, enabling material hardness identification via contact deformation.
Tao Yue, Yuyin Zhang, Yuanjie Gan, Chengzhi Hu, Yue Wang   +4 more
wiley   +1 more source

Endothelial Cells Expressing Endothelial and Mesenchymal Cell Gene Products in Lung Tissue From Patients With Systemic Sclerosis-Associated Interstitial Lung Disease. [PDF]

, 2016
OBJECTIVE: To examine whether lung endothelial cells (ECs) from patients with systemic sclerosis (SSc)-associated interstitial lung disease (ILD) express mesenchymal cell-specific proteins and gene transcripts, indicative of the occurrence of endothelial-
Arciniegas, Beon, Cooley, Del Galdo, Falke, Gabrielli, Gilbane, Good, Goumans, Hashimoto, Herzog, Herzog, Hinz, Hinz, Humphreys, Jimenez, Katsumoto, Kendall, Kramann, Lamouille, LeBleu, Li, Li, Marelli-Berg, Matucci-Cerinic, McAnulty, Medici, Meeteren, Nolan, Pattanaik, Piera-Velazquez, Piera-Velazquez, Poslethwaite, Ranchoux, Rieder, Strieter, Varga, Veraldi, Wells, Yoshimatsu, Zeisberg, Zeisberg   +41 more
core   +2 more sources

Comment on: a novel transition clinic structure for adolescent and young adult patients with childhood onset rheumatic disease improves transition outcomes

Pediatric Rheumatology Online Journal, 2022
Mislav Radić
doaj   +1 more source

Therapeutic Promise of Hyaluronidase in Systemic Sclerosis: A Systematic Review

Dermatology Practical & Conceptual
Introduction: Systemic sclerosis, also known as scleroderma, is a chronic disease marked by autoimmune-mediated damage to connective tissues leading to vascular damage, tissue injury, and fibrosis.
Anika Pulumati, Rachel Lin, Scott Elman
doaj   +1 more source

Mesenchymal stem cell as a novel approach to systemic sclerosis; current status and future perspectives

Cell Regeneration, 2020
Systemic sclerosis is a rare chronic autoimmune disease with extensive microvascular injury, damage of endothelial cells, activation of immune responses, and progression of tissue fibrosis in the skin and various internal organs.
Mina Abedi, Sepideh Alavi-Moghadam, Moloud Payab, Parisa Goodarzi, Fereshteh Mohamadi-jahani, Forough Azam Sayahpour, Bagher Larijani, Babak Arjmand   +7 more
doaj   +1 more source

Treatment Algorithms for Systemic Sclerosis According to Experts

Arthritis & Rheumatology, 2018
There is a lack of agreement regarding treatment for many aspects of systemic sclerosis (SSc). We undertook this study to generate SSc treatment algorithms endorsed by a high percentage of SSc experts.
A. Fernández-Codina, K. M. Walker, J. Pope   +2 more
semanticscholar   +1 more source

Understanding the Housing and Support Experience of People With Complex Disability in Australia: A Qualitative Analysis of Submissions to the Disability Royal Commission

Australian Journal of Social Issues, EarlyView.
ABSTRACT In 2019, the Australian government established the Royal Commission into Violence, Abuse, Neglect and Exploitation of People with Disability (‘Disability Royal Commission’, DRC) to investigate widespread mistreatment of people with disability. Nearly 10,000 people with disability, their families and supporters engaged with the DRC.
Kate D'Cruz, Fiona Carey, Libby Witts, Jessie Spence, Peter Mulherin, Megan Topping, Di Winkler, Jacinta Douglas   +7 more
wiley   +1 more source