Results 201 to 210 of about 1,679,247 (398)

Understanding the Housing and Support Experience of People With Complex Disability in Australia: A Qualitative Analysis of Submissions to the Disability Royal Commission

Australian Journal of Social Issues, EarlyView.
ABSTRACT In 2019, the Australian government established the Royal Commission into Violence, Abuse, Neglect and Exploitation of People with Disability (‘Disability Royal Commission’, DRC) to investigate widespread mistreatment of people with disability. Nearly 10,000 people with disability, their families and supporters engaged with the DRC.
Kate D'Cruz, Fiona Carey, Libby Witts, Jessie Spence, Peter Mulherin, Megan Topping, Di Winkler, Jacinta Douglas   +7 more
wiley   +1 more source

Establishment of a humanized SCA2 mouse model carrying a CAA disruption preventing CAG repeat expansion in pathogenic genes

Animal Models and Experimental Medicine, EarlyView.
In this study, we established a mouse model in which CAG repeats do not undergo microsatellite instability (MSI) across generations. A humanized ATXN2 cDNA with four CAA interruptions within 73 CAG expansions was inserted into the Rosa26 locus of C57BL/6J mice. At the same time, a 23 CAG control mouse model was also generated.
Yao Zhang, Yufei Li, Lin Zhang, Zhaoqing Li, Keqin Lin, Kai Huang, Zhaoqing Yang, Shaohui Ma, Hao Sun, Xiaochao Zhang   +9 more
wiley   +1 more source

Clinical and serological comparison of 17 chronic progressive systemic sclerosis (PSS) and 17 CREST syndrome patients matched for sex, age, and disease duration. [PDF]

, 1984
Daniel E. Furst, P. Clements, M. P. Saab, Millie Sterz, Harold E. Paulus   +4 more
openalex   +1 more source

Standardisation of nailfold capillaroscopy for the assessment of patients with Raynaud's phenomenon and systemic sclerosis.

Autoimmunity Reviews, 2020
V. Smith, A. Herrick, F. Ingegnoli, N. Damjanov, Angelis, C. Denton, O. Distler, Karinna Espejo, I. Foeldvari, T. Frech, Boris Garro, M. Gutierrez, G. Gyger, E. Hachulla, R. Hesselstrand, A. Iagnocco, C. Kayser, K. Melsens, U. Müller-Ladner, C. Pizzorni, M. Radić, V. Riccieri, Marcus H Snow, W. Stevens, A. Sulli, J. V. van Laar, M. Vonk, A. Vanhaecke, M. Cutolo   +28 more
semanticscholar   +1 more source

Multiple low dose streptozotocin‐induced diabetes as a model for studying autoimmune diabetes in humans

Animal Models and Experimental Medicine, EarlyView.
Multiple low dose streptozotocin‐induced diabetes is a valuable animal model of diabetes type 1. It should be improved by further research on autoantigens, microbiota and mucosal immune cells from the gut, but also from other organs. Abstract The autoimmune response directed against pancreatic β cells is the most essential pathogenic process in type 1 ...
Ivan Koprivica, Suzana Stanisavljević, Dragica Mićanović, Ivana Stojanović, Đorđe Miljković   +4 more
wiley   +1 more source

Nifedipine Treatment for Pulmonary Hypertension in a Patient with Systemic Sclerosis [PDF]

, 1983
Stephen Ocken, Elizabeth Reinitz, Joel A. Strom   +2 more
openalex   +1 more source

Research progress on traditional Chinese medicine animal models of post‐stroke depression and pathological insights

Animal Models and Experimental Medicine, EarlyView.
Post‐stroke depression (PSD) animal model of traditional Chinese medicine (TCM) combined with disease and syndrome often uses western medicine surgery (including: middle cerebral artery embolization to construct cerebral ischemia, or brain injection of collagenase to construct cerebral hemorrhage) combined with other methods (including: isolation ...
Jielin Wang, Wenlu Ma, Wei Wu, Yujuan Fu, Hui Li   +4 more
wiley   +1 more source

High‐Dose Pulse Glucocorticoid Treatment Prevents White Matter Spinal Cord Pseudoatrophy in Newly Diagnosed Multiple Sclerosis

Annals of Neurology, EarlyView.
Objective Spinal cord (SC) atrophy correlates with and predicts the underlying progressive biology in active and non‐active multiple sclerosis (MS), thereby providing a biomarker for clinical trials and patient management. Initiation of disease‐modifying therapy (DMT) may be followed by early pronounced central nervous system (CNS) volume loss due to ...
Simone Sacco, Nico Papinutto, Vinicius A. Schoeps, Shuiting Cheng, William A. Stern, Haojun Zhao, Antje Bischof, Eduardo Caverzasi, Manula Dombagahawatta, Jeremy Juwono, Amit Akula, Christian Cordano, Alexandra Beaudry‐Richard, Refujia Gomez, Meagan Harms, Adam Santaniello, Riley M. Bove, Jeffrey M. Gelfand, Douglas S. Goodin, Ari J. Green, Jorge R. Oksenberg, Emmanuelle Waubant, Michael R. Wilson, Scott S. Zamvil, Bruce A. C. Cree, Stephen L. Hauser, Roland G. Henry   +26 more
wiley   +1 more source

Polymyositis and Acute Onset Systemic Sclerosis in a Patient with Primary Biliary Cirrhosis: A Clinical Syndrome Similar to the Mixed Connective Tissue Disease [PDF]

, 1981
Owen Epstein, Andrew K. Burroughs, Sheila Sherlock   +2 more
openalex   +1 more source

The FindMNDBiomarker Program: Protein Changes in Motor Neuron Disease/Amyotrophic Lateral Sclerosis Postmortem Tissue and Biofluids

Annals of Neurology, EarlyView.
Objective Biomarkers of disease pathogenesis are critically needed for amyotrophic lateral sclerosis (ALS) to facilitate diagnosis and patient stratification into appropriate therapeutic trials. Proteomic studies offer significant potential to advance this, but reproducibility across laboratories is a key component toward identifying protein changes ...
Gabrielle L. Adler, Matthew C. Kiernan, Rachel H. Tan   +2 more
wiley   +1 more source