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British Journal of Hospital Medicine, 2019
Systemic sclerosis is a complex autoimmune connective tissue disease which carries a significant burden of disease-related morbidity including potentially life-threatening complications. Systemic sclerosis can affect all the major organs and therefore, although the disease is uncommon, many hospital-based specialists are involved in patient care ...
Hughes, Michael; id_orcid 0000-0003-3361-4909 +1 more
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Systemic sclerosis is a complex autoimmune connective tissue disease which carries a significant burden of disease-related morbidity including potentially life-threatening complications. Systemic sclerosis can affect all the major organs and therefore, although the disease is uncommon, many hospital-based specialists are involved in patient care ...
Hughes, Michael; id_orcid 0000-0003-3361-4909 +1 more
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Cardiac involvement in systemic sclerosis: Getting to the heart of the matter.
Baillière's Best Practice & Research : Clinical Rheumatology, 2021Primary systemic sclerosis heart involvement (pSHI) is an important disease manifestation that accounts for a significant proportion of systemic sclerosis (SSc)-associated mortality.
C. Bruni, L. Ross
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The Lancet Rheumatology, 2021
BACKGROUND Interstitial lung disease (ILD) is the most common cause of death in systemic sclerosis. To date, the progression of systemic sclerosis-associated ILD is judged by the accrual of lung damage on CT and pulmonary function tests.
C. Bergmann +23 more
semanticscholar +1 more source
BACKGROUND Interstitial lung disease (ILD) is the most common cause of death in systemic sclerosis. To date, the progression of systemic sclerosis-associated ILD is judged by the accrual of lung damage on CT and pulmonary function tests.
C. Bergmann +23 more
semanticscholar +1 more source
Journal of the American Academy of Dermatology, 1993
Systemic sclerosis affects the connective tissue of various organs. It is characterized by alteration of the microvasculature with a dense inflammatory cellular infiltrate, followed by massive deposition of collagen. This review discusses diagnostic criteria, clinical subsets, survival data, clinical evaluation, epidemiology, pathogenesis ...
M I, Perez, S R, Kohn
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Systemic sclerosis affects the connective tissue of various organs. It is characterized by alteration of the microvasculature with a dense inflammatory cellular infiltrate, followed by massive deposition of collagen. This review discusses diagnostic criteria, clinical subsets, survival data, clinical evaluation, epidemiology, pathogenesis ...
M I, Perez, S R, Kohn
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The Lancet Rheumatology, 2021
BACKGROUND Preliminary criteria for the very early diagnosis of systemic sclerosis (VEDOSS) have been previously proposed to identify signs and symptoms in patients with Raynaud's phenomenon.
S. Bellando-Randone +14 more
semanticscholar +1 more source
BACKGROUND Preliminary criteria for the very early diagnosis of systemic sclerosis (VEDOSS) have been previously proposed to identify signs and symptoms in patients with Raynaud's phenomenon.
S. Bellando-Randone +14 more
semanticscholar +1 more source
Best Practice & Research Clinical Rheumatology, 2002
Systemic sclerosis (SSc) presents with a great deal of variability from patient to patient and classification and subset criteria will be analysed and discussed. SSc has been reported in people from all over the world. The prevalence and incidence, however, varies from country to country and within the same country in different ethnic groups.
VALENTINI, Gabriele, BLACK C.
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Systemic sclerosis (SSc) presents with a great deal of variability from patient to patient and classification and subset criteria will be analysed and discussed. SSc has been reported in people from all over the world. The prevalence and incidence, however, varies from country to country and within the same country in different ethnic groups.
VALENTINI, Gabriele, BLACK C.
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Systemic sclerosis-associated interstitial lung disease.
The Lancet Respiratory Medicine, 2020Systemic sclerosis is an autoimmune connective tissue disease, which is characterised by immune dysregulation and progressive fibrosis that typically affects the skin, with variable internal organ involvement.
A. Perelas +3 more
semanticscholar +1 more source
Rheumatic Disease Clinics of North America, 1990
Systemic sclerosis is a disease characterized by several distinctive features. This disease spares children, and its incidence increases steadily with age. Women are affected more than men, especially during childbearing years. Although there is no overall racial predilection, SSc occurs most frequently and severely in young black women.
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Systemic sclerosis is a disease characterized by several distinctive features. This disease spares children, and its incidence increases steadily with age. Women are affected more than men, especially during childbearing years. Although there is no overall racial predilection, SSc occurs most frequently and severely in young black women.
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Calcinosis in systemic sclerosis
Current Opinion in Rheumatology, 2022Purpose of review To provide updated information on the prevalence, pathogenesis, diagnostics, and therapeutics of calcinosis cutis associated with systemic sclerosis (SSc). Recent findings Observational studies show ethnic and ...
Srijana, Davuluri +2 more
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Microchimerism and Systemic Sclerosis
International Archives of Allergy and Immunology, 2001Systemic sclerosis (SSc) is a connective tissue disease characterized by progressive fibrosis of the skin and internal organs. SSc is an immunologically mediated disease. A prominent immunological abnormality in SSc patients is the presence of circulating autoantibodies against a variety of nuclear proteins.
SCALETTI, CRISTINA +4 more
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