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Systemic sclerosis

Best Practice & Research Clinical Rheumatology, 2002
Systemic sclerosis (SSc) presents with a great deal of variability from patient to patient and classification and subset criteria will be analysed and discussed. SSc has been reported in people from all over the world. The prevalence and incidence, however, varies from country to country and within the same country in different ethnic groups.
VALENTINI, Gabriele, BLACK C.
  +6 more sources

Systemic sclerosis

British Journal of Hospital Medicine, 2019
Systemic sclerosis is a complex autoimmune connective tissue disease which carries a significant burden of disease-related morbidity including potentially life-threatening complications. Systemic sclerosis can affect all the major organs and therefore, although the disease is uncommon, many hospital-based specialists are involved in patient care ...
Hughes, Michael, Herrick, Ariane L
openaire   +5 more sources

Systemic sclerosis

Journal of the American Academy of Dermatology, 1993
Systemic sclerosis affects the connective tissue of various organs. It is characterized by alteration of the microvasculature with a dense inflammatory cellular infiltrate, followed by massive deposition of collagen. This review discusses diagnostic criteria, clinical subsets, survival data, clinical evaluation, epidemiology, pathogenesis ...
M I, Perez, S R, Kohn
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SYSTEMIC SCLEROSIS (SCLERODERMA)

Acta Clinica Belgica, 2007
Systemic sclerosis is a rare and often debilitating disorder characterized by a pathological triad: increased deposition of extracellular matrix and collagen in tissues, microvascular damage and dysfunction, and immune activation as evidenced by inflammation and frequent occurrence of autoantibodies.
Roufosse, Florence   +1 more
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Systemic Sclerosis

Rheumatic Disease Clinics of North America, 1990
Systemic sclerosis is a disease characterized by several distinctive features. This disease spares children, and its incidence increases steadily with age. Women are affected more than men, especially during childbearing years. Although there is no overall racial predilection, SSc occurs most frequently and severely in young black women.
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Childhood systemic sclerosis

Current Opinion in Rheumatology, 2007
Juvenile systemic sclerosis has a variety of clinical manifestations, sometimes different from the adult form. Early recognition, proper classification and treatment may improve the long-term outcome.A large multicenter study coordinated by the Pediatric Rheumatology European Society has yielded important information on the epidemiology and clinical ...
Francesco, Zulian, Giorgia, Martini
openaire   +2 more sources

Progressive Systemic Sclerosis

The British Journal of Radiology, 1965
Fifty-two cases of scleroderma have been investigated in the Diagnostic Radiology Department. The incidence of the various systemic manifestations has been discussed. It has been found that over 50 per cent of the patients had positive radiological changes in the colon. These are specific for scleroderma and consist of wide-necked pseudo diverticula in
R A, Harper, D C, Jackson
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Microchimerism and Systemic Sclerosis

International Archives of Allergy and Immunology, 2001
Systemic sclerosis (SSc) is a connective tissue disease characterized by progressive fibrosis of the skin and internal organs. SSc is an immunologically mediated disease. A prominent immunological abnormality in SSc patients is the presence of circulating autoantibodies against a variety of nuclear proteins.
SCALETTI, CRISTINA   +4 more
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Systemic Sclerosis, Scleroderma

2006
Abstract The scleroderma spectrum of disorders includes several diseases that have Raynaud’s phenomenon or skin sclerosis in common, comprising (1) localized cutaneous scleroderma; (2) systemic sclerosis (SSc)—the most important form of scleroderma—limited cutaneous SSc, diffuse cutaneous SSc, and overlap syndromes (with features of ...
Christopher P. Denton, Carol M. Black
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Systemic Sclerosis

2009
Systemic sclerosis and its subtypes differ significantly from other diseases in rheumatology and clinical immunology, as the aberrant activation of the immune system does not result in an inflammation-driven destruction but in a progressive matrix synthesis, especially of the skin. Owing to the recently established networks in Germany (DNSS) as well as
openaire   +2 more sources

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