Results 21 to 30 of about 951,952 (191)

Efficacy of belimumab combined with rituximab in severe systemic lupus erythematosus: study protocol for the phase 3, multicenter, randomized, open-label Synbiose 2 trial

Trials, 2022
Background Belimumab, an anti-B-cell activating factor antibody, is approved for the treatment of auto-antibody positive systemic lupus erythematosus with a high degree of disease activity.
Mieke van Schaik, Eline J. Arends, Darius Soonawala, Ellen van Ommen, Karina de Leeuw, Maarten Limper, Pieter van Paassen, Tom W. J. Huizinga, René E. M. Toes, Cees van Kooten, Joris I. Rotmans, Ton J. Rabelink, Y. K. Onno Teng   +12 more
doaj   +1 more source

The eye in systemic vasculitis [PDF]

Clinical Medicine, 2004
The term 'vasculitis' includes a wide range of disorders characterised by inflammation of the wall of blood vessels, sometimes with necrosis, leading to ischaemia of the affected organ. The exact pathogenesis of most of these vasculitides is not fully understood and although the presence of circulating auto-antibodies seems to be a common feature among
Victor, Menezo, Susan, Lightman
openaire   +2 more sources

Highly Sensitive Flow Cytometric Detection of Residual B-Cells After Rituximab in Anti-Neutrophil Cytoplasmic Antibodies-Associated Vasculitis Patients

Frontiers in Immunology, 2020
BackgroundB-cell depletion with rituximab (RTX) is an effective treatment for anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) patients.
Laura S. van Dam, Jelle M. Oskam, Sylvia W. A. Kamerling, Eline J. Arends, O. W. Bredewold, Magdalena A. Berkowska, Jacques J. M. van Dongen, Ton J. Rabelink, Cees van Kooten, Y. K. Onno Teng   +9 more
doaj   +1 more source

The Impact of High Dose Glucocorticoids on Bone Health and Fracture Risk in Systemic Vasculitides

Frontiers in Endocrinology, 2022
Systemic vasculitides are a range of conditions characterized by inflammation of blood vessels which may manifest as single organ or life-threatening multisystem disease.
Christopher David Box, Owen Cronin, Owen Cronin, Barbara Hauser, Barbara Hauser   +4 more
doaj   +1 more source

Stroke frequency, associated factors, and clinical features in primary systemic vasculitis: a multicentric observational study. [PDF]

J Neurol
Objectives: The cerebral vessels may be affected in primary systemic vasculitis (PSV), but little is known about cerebrovascular events (CVEs) in this population.
Geraldes R, Santos M, Ponte C, Craven A, Barra L, Robson JC, Hammam N, Springer J, Henes J, Hocevar A, Putaala J, Santos E, Rajasekhar L, Daikeler T, Karadag O, Costa A, Khalidi N, Pagnoux C, Canhão P, Melo TPE, Fonseca AC, Ferro JM, Fonseca JE, Suppiah R, Watts RA, Grayson P, Merkel PA, Luqmani RA, DCVAS Study Group.   +28 more
europepmc   +4 more sources

Immune-Complex Allergic Vasculitis in Association with the Immune-Complex Allergic Vasculitis in Association with the Development of Transverse Myelitis: A Case Report [PDF]

, 1996
A severe vasculitis, probably therapy related, in a sixty-four-year-old man being treated for possible subacute bacterial endocarditis, was associated with the development of transverse myelitis.
Huehns, Tanya Y., Nikol, Sigrid, Pilz, Günter, Scheidt, Wolfgang von, Günter Pilz, Wolfgang von Scheidt, Sigrid Nikol, Tanya Y. Huehns   +7 more
core   +1 more source

Vasculitic peripheral neuropathy [PDF]

Reviews in Clinical Medicine, 2014
Primary systemic vasculitis in pre-capillary arteries is associated with peripheral neuropathy. In some types of systematic vasculitis about 60 % of patients have peripheral nervous system (PNS) involvement.
Mona Amini, Reza Boostani, Maryam Sahebari   +2 more
doaj   +3 more sources

Classification of systemic vasculitis: evolution from eponyms to modern criteria

Терапевтический архив, 2022
Systemic vasculitis is a manifold group of systemic autoimmune diseases characterized by the inflammation of the blood vessels. The first clinical cases of systemic vasculitis were described in the Middle Ages, and most of the currently recognised ...
Nikolay M. Bulanov, Pavel I. Novikov, Mariia A. Litvinova, Sergey V. Moiseev   +3 more
doaj   +1 more source

Incidence of Systemic Vasculitis and Clinical Outcomes in Systemic Sclerosis: 2-Years Follow-Up of Asymptomatic Positive for Anti-Neutrophilic Cytoplasmic Antibody. [PDF]

Clin Cosmet Investig Dermatol
Raiwin Suwannamajo, Ajanee Mahakkanukrauh, Siraphop Suwannaroj, Chingching Foocharoen Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, ThailandCorrespondence: Chingching Foocharoen, Department of Medicine, Faculty of ...
Suwannamajo R, Mahakkanukrauh A, Suwannaroj S, Foocharoen C.   +3 more
europepmc   +2 more sources

Takayasu arteritis in childhood: retrospective experience from a tertiary referral centre in the United Kingdom. [PDF]

, 2015
Takayasu arteritis (TA) is an idiopathic large-vessel vasculitis affecting the aorta and its major branches. Although the disease rarely affects children, it does occur, even in infants.
McMahon, AM, Paul A Brogan, Pavla Dolezalova, Giulia Varnier, Despina Eleftheriou, Eleftheriou, D, Varnier, G, Muthana Al-Obaidi, Al-Obaidi, M, Dolezalova, P, Brogan, PA, Anne-Marie McMahon   +11 more
core   +1 more source