Results 81 to 90 of about 4,082,982 (293)

A hybrid methodology to enable the verification of temporal properties as system-level

, 2019
SoCs haben unterschiedliche Komplexitätsgrade und zudem werden kommende Generationen zunehmend komplexer. Allerdings bedeutet diese Zunahme an Komplexität und Funktionalität auch, dass die Lücke zwischen der Entwicklung des Designs und die Notwendigkeit der Verifizierung desselben immer größer wird.
openaire   +3 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Analysis of Healthcare Systems by Using Systemic Approach

Complexity, 2019
National healthcare systems in all countries do not act effectively. Therefore, especially strategies for introducing organizational innovation to public organization should be considered. The problem is how to organize the research in this field. One of
Andrzej Bielecki, Sylwia Nieszporska
doaj   +1 more source

Approaches and Challenges of Engineering Implantable Microelectromechanical Systems (MEMS) Drug Delivery Systems for in Vitro and in Vivo Applications

Micromachines, 2012
Despite the advancements made in drug delivery systems over the years, many challenges remain in drug delivery systems for treating chronic diseases at the personalized medicine level.
Ken-Tye Yong, Indrajit Roy, Rui Hu, Peiyi Song, Danny Jian Hang Tng   +4 more
doaj   +1 more source

Four-level N-scheme crossover resonances in Rb saturation spectroscopy in magnetic fields

, 2015
We perform saturated absorption spectroscopy on the D$\_2$ line for room temperature rubidium atoms immersed in magnetic fields within the 0.05-0.13 T range.
Arimondo, Ennio, Ciampini, Donatella, Rizzo, Carlo, Scotto, Stefano   +3 more
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Influence of Enzymatic Acylation on the Stability and Antioxidant Properties of Cyanidin-3-O-Glucoside in Both Aqueous and Lipid Systems

Molecules
Cyanidin-3-O-glucoside (C3G) was used as a substrate for enzymatic acylation, and different compounds (methyl n-octanoate and methyl salicylate) were selected as acyl donors.
Ziwei Ye, Mingyun Liu, Jingmei Lyu, Han Rong, Lujing Gan   +4 more
doaj   +1 more source

Impact of Control System Structure and Performance of Inventory Goods Flow System with Long-Variable Delay

Elektronika ir Elektrotechnika, 2018
In this paper, we use a mathematical model of a inventory system with time-varying delivery delay and three control systems  in order to compare their properties for the goods flow optimization problem in the inventory systems.
Ewelina Cholodowicz, Przemyslaw Orlowski
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Quality-aware model-driven service engineering [PDF]

, 2008
Service engineering and service-oriented architecture as an integration and platform technology is a recent approach to software systems integration.
Barrett, Ronan, Boskovic, Marko, Hasselbring, Wilhelm, Pahl, Claus   +3 more
core