Results 151 to 160 of about 14,311,112 (298)

Coalitions as Prevention Infrastructure for Youth Substance Use: Coordinated, Local Relevance, and Sustainability. [PDF]

J Public Health Manag Pract
Roehler DR, Moreno C, Watts B, Schainker LM, Koffkey C, Baranek B, Fockler L, Spieckerman A, Hardin K.   +8 more
europepmc   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

2015 CPES Annual Report

, 2015
In its efforts to develop power processing systems to take electricity to the next step, CPES has developed research expertise encompassing five technology areas: (1) power conversion technologies and architectures; (2) power electronics components; (3 ...
Center for Power Electronics Systems, Uncork-it, Inc.   +1 more
core  

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

2016 CPES Annual Report

, 2016
In its effort to develop power processing systems to take electricity to the next step, CPES has cultivated research expertise encompassing five technology areas: (1) power conversion technologies and architectures; (2) power electronics components; (3 ...
Center for Power Electronics Systems, Uncork-it, Inc.   +1 more
core  

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Annual progress report 2013: CGIAR Research Program on Dryland Systems (Dryland Systems)

, 2013
Annual progress report 2013: CGIAR Research Program on Dryland Systems (Dryland ...
CGIAR Research Program on Dryland Systems
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Connecting behaviour change to systems change: rethinking climate action in scientific societies. [PDF]

Int J Behav Nutr Phys Act
Crielaard L, O'Mara J, Dijkstra C, Waterlander W.   +3 more
europepmc   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source