Results 61 to 70 of about 698,481 (205)
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Sustainability and resilience: toward a systems approach
A comprehensive systems approach is essential for effective decision making with regard to global sustainability, since industrial, social, and ecological systems are closely linked. Despite efforts to reduce unsustainability, global resource consumption
Joseph Fiksel
doaj
Improvement interventions: To what extent are they manifestations of social defences?
Orientation: The statistical record of change and improvement interventions to deliver on expectations is notoriously poor. Yet, new interventions are started constantly.
Jeremias J. de Klerk
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Building Models for a Scientific Approach to Problem Solving in Production Systems
The paper presents a model of scientific approach to problem solving. The model is based on a gradual approach, preparation, resolution, verification and improvement of solutions.
Veljko Kondić +3 more
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Transitional Electrodes in Electrowetting-Based Droplet Dispensing
Digital microfluidic systems based on electrowetting-on-dielectric technology, particularly valuable in producing and manipulating microdroplets steadily and consistently, have experienced notable advancements in recent years. In this paper, experimental
Wei Wang +3 more
doaj +1 more source
Results of a cluster randomized trial testing the Systems Analysis and Improvement Approach to increase cervical cancer screening in family planning clinics in Mombasa County, Kenya. [PDF]
Eastment MC +9 more
europepmc +1 more source

