Results 191 to 200 of about 1,150,837 (304)

Integrative systems biology approaches for analyzing microbiome dysbiosis and species interactions. [PDF]

Brief Bioinform
Sabih Ur Rehman S, Nasar MI, Mesquita CS, Al Khodor S, Notebaart RA, Ott S, Mundra S, Arasardanam RP, Muhammad K, Alam MT.   +9 more
europepmc   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

An integrative systems-biology approach defines mechanisms of Alzheimer's disease neurodegeneration. [PDF]

Nat Commun
Leventhal MJ, Zanella CA, Kang B, Peng J, Gritsch D, Liao Z, Bukhari H, Wang T, Pao PC, Danquah S, Benetatos J, Nehme R, Farhi S, Tsai LH, Dong X, Scherzer CR, Feany MB, Fraenkel E.   +17 more
europepmc   +1 more source

Data Integration and Analysis for Medical Systems Biology [PDF]

, 2004
Hans van Beek
openalex   +1 more source

Systems biology or the biology of systems: routes to reducing hunger [PDF]

New Phytologist, 2008
P. L. Mitchell, Anaida B. Ferrer, Florence R. Danila, J. E. Sheehy, D. Gunawardana, K. G. Tan   +5 more
openaire   +3 more sources

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

Editorial: Natural products and immune inflammation: mechanistic understanding based on systems biology. [PDF]

Front Pharmacol
Ma Z, Li X.
europepmc   +1 more source

Pollination and Reproductive Biology of Twelve Species of Neotropical Malpighiaceae: Stigma Morphology and its Implications for the Breeding System [PDF]

, 2004
Maria Rosângela Sigrist
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Systems biology approaches investigating mitochondrial dysfunction in cyanotic heart disease: a systematic review. [PDF]

EBioMedicine
Elbatarny M, Lu YT, Hu M, Coles J, Mital S, Ross-White A, Honjo O, Barron DJ, Gramolini AO.   +8 more
europepmc   +1 more source