Results 191 to 200 of about 2,957,126 (345)

Numerical Methods for Parameter Estimation in Dynamical Systems with Noise with Applications in Systems Biology [PDF]

, 2017
Andreas Sommer
openalex   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Bioinformatics and Systems Biology

BioTechniques, 2009
Lynne Lederman
doaj   +1 more source

Systems biology and microbiome innovations for personalized diabetic retinopathy management. [PDF]

NPJ Syst Biol Appl
Aminian-Dehkordi J, Montazeri F, Tamadon A, Mofrad MRK.   +3 more
europepmc   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Unifying pharmacology, systems biology, and regenerative medicine to advance personalized therapies. [PDF]

Front Pharmacol
Martins A.
europepmc   +1 more source

The limited role of genetics explaining the atherosclerotic process and coronary artery disease and the holistic perspective of systems biology

, 2018
George Louridas
openalex   +1 more source

Supplementary Table 2 from The Exomes of the NCI-60 Panel: A Genomic Resource for Cancer Biology and Systems Pharmacology

, 2023
Ogan D. Abaan, Eric C. Polley, Sean Davis, Yuelin J. Zhu, Sven Bilke, Robert L. Walker, Marbin Pineda, Yevgeniy Gindin, Yuan Jiang, William C. Reinhold, Susan L. Holbeck, Richard Simon, James H. Doroshow, Yves Pommier, Paul S. Meltzer   +14 more
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Editorial: Systems biology, women in science 2021/22: translational systems biology and in silico trials

Frontiers in Systems Biology, 2023
Jane A. Leopold, Madhavi K. Ganapathiraju, Naveena Yanamala   +2 more
doaj   +1 more source