Results 191 to 200 of about 2,989,026 (346)

Roadmap for a Systems Biology Initiative in Iran. [PDF]

J Med Signals Sens
Kamali Z, Jalilvandnejad A, Falenji B, Zarei P, Lotfi M, Hadizadeh F, Vaez A.   +6 more
europepmc   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Molecular Systems Biology at 20: reflecting on the past, envisioning the future. [PDF]

Mol Syst Biol
Bheda P, Hou J, Aebersold R, Alon U, Bader JS, Bardwell L, Liu ET, Locke JCW, Mann M, Millar AJ, Naef F, Pilpel Y, Shamir R, Vitkup D.   +13 more
europepmc   +1 more source

A Systems Biology Approach in Therapeutic Response Study for Different Dosing Regimens—a Modeling Study of Drug Effects on Tumor Growth using Hybrid Systems

, 2012
Xiangfang Li, Lijun Qian, Michale L. Bittner, Edward R. Dougherty   +3 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Bioinformatics and Systems Biology

BioTechniques, 2009
Lynne Lederman
doaj   +1 more source

Systems biology and microbiome innovations for personalized diabetic retinopathy management. [PDF]

NPJ Syst Biol Appl
Aminian-Dehkordi J, Montazeri F, Tamadon A, Mofrad MRK.   +3 more
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Exploring the Mechanism of Traditional Chinese Medicine Improving Immune and Inflammatory Responses in Systemic Sclerosis Based on Systems Biology and Cell Experiments

Xiang Ding, Jian Liu, Xiaolu Chen, Xianheng Zhang   +3 more
openalex   +1 more source

Supplementary Figure 1 from A Systems Biology Approach Identifies SART1 as a Novel Determinant of Both 5-Fluorouracil and SN38 Drug Resistance in Colorectal Cancer

, 2023
Wendy L. Allen, Leanne Stevenson, Vicky M. Coyle, Puthen V. Jithesh, Irina Proutski, Gail Carson, Melita A. Gordon, Heinz-Josef D. Lenz, Sandra Van Schaeybroeck, Daniel B. Longley, Patrick G. Johnston   +10 more
openalex   +1 more source