Results 201 to 210 of about 25,508,313 (370)

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

The viral killer system in yeast: from molecular biology to application [PDF]

, 2002
Manfred Schmitt
openalex   +1 more source

Applications of Magnetic Resonance in Model Systems: Tumor Biology and Physiology

, 2000
Robert J. Gillies, Zaver M. Bhujwalla, Jeffrey L. Evelhoch, Michael Garwood, M. Neema, Simon P. Robinson, Christopher H. Sotak, Boudewijn van der Sanden   +7 more
openalex   +1 more source

Understanding biology through intelligent systems. [PDF]

, 2002
Igor Jurišica, Dennis A. Wigle
openalex   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

The IGF System: Molecular Biology, Physiology, and Clinical Applications

, 2000
Michael Berry, Terry G. Unterman
openalex   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Evolvable Systems: From Biology to Hardware

, 2000
Julian F. Miller, A. Thompson, P.F. Thomson, Terence C. Fogarty   +3 more
openalex   +1 more source

Meeting Review: Intelligent Systems for Molecular Biology 2002 (ISMB02) [PDF]

, 2002
K. Cara Woodwark
openalex   +1 more source

Cross-linking mass spectrometry: methods and applications in structural, molecular and systems biology

Nature Structural & Molecular Biology, 2018
Francis J. O’Reilly, J. Rappsilber
semanticscholar   +1 more source