Results 201 to 210 of about 2,957,126 (345)

Organokine-Mediated Crosstalk: A Systems Biology Perspective on the Pathogenesis of MASLD-A Narrative Review. [PDF]

Int J Mol Sci
Maria Barbalho S, Laurindo LF, Valenti VE, Méndez-Sánchez N, Ramírez-Mejía MM, Goulart RA.   +5 more
europepmc   +1 more source

ANDDigest: a text-mining based computer system for generating digests in the field of biology

, 2020

openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Semantic systems biology of prokaryotes : heterogeneous data integration to understand bacterial metabolism

, 2019
Jesse C. J. van Dam
openalex   +2 more sources

InFlo: a novel systems biology framework identifies cAMP-CREB1 axis as a key modulator of platinum resistance in ovarian cancer [PDF]

, 2016
Nevenka Dimitrova, Anil Belur Nagaraj, Abolfazl Razi, Salendra Singh, Sitharthan Kamalakaran, Nilanjana Banerjee, Peronne Joseph, AR Mankovich, Pooja Mittal, Analisa DiFeo, Vinay Varadan   +10 more
openalex   +1 more source

Computational and Systems Biology [PDF]

Molecular BioSystems, 2009
M Madan, Babu, Hirotada, Mori
openaire   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Unravelling the Complexity of Sarcopenia Through a Systems Biology Approach. [PDF]

Int J Mol Sci
Ceyhan AB, Altay O, Zhang C, Temel SG, Turkez H, Mardinoglu A.   +5 more
europepmc   +1 more source

Category of Metabolic-Replication Systems in Biology and Medicine

, 2012
Ion C. Băianu
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source