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Systems Biology and the Biology of Systems
Physiology, 2010When I sit down to write an editorial for Physiology, I flatter myself that the two or three people who will ultimately read it want to hear my thoughts on a “big” topic. It strikes me that, within the rarefied realm of academic biology, there few bigger topics, or at least few topics more ...
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2018
The aim of this volume is to encourage the use of systems-level methodologies to contribute to the improvement of human-health . We intend to motivate biomedical researchers to complement their current theoretical and empirical practice with up-to-date systems biology conceptual approaches.
María Elena, Álvarez-Buylla Roces +4 more
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The aim of this volume is to encourage the use of systems-level methodologies to contribute to the improvement of human-health . We intend to motivate biomedical researchers to complement their current theoretical and empirical practice with up-to-date systems biology conceptual approaches.
María Elena, Álvarez-Buylla Roces +4 more
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2010
Cancer is a complex and heterogeneous disease, not only at a genetic and biochemical level, but also at a tissue, organism, and population level. Multiple data streams, from reductionist biochemistry in vitro to high-throughput "-omics" from clinical material, have been generated with the hope that they encode useful information about phenotype and ...
Dana, Faratian +4 more
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Cancer is a complex and heterogeneous disease, not only at a genetic and biochemical level, but also at a tissue, organism, and population level. Multiple data streams, from reductionist biochemistry in vitro to high-throughput "-omics" from clinical material, have been generated with the hope that they encode useful information about phenotype and ...
Dana, Faratian +4 more
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Annals of the New York Academy of Sciences, 2005
Abstract: As more detailed molecular information accumulates on the biology of the heart and other complex systems in health and disease, the need for new integrative analyses and tools is growing. Systems biology and bioengineering seek to use high‐throughput technologies and integrative computational analysis to construct networks of the ...
Andrew D, McCulloch +1 more
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Abstract: As more detailed molecular information accumulates on the biology of the heart and other complex systems in health and disease, the need for new integrative analyses and tools is growing. Systems biology and bioengineering seek to use high‐throughput technologies and integrative computational analysis to construct networks of the ...
Andrew D, McCulloch +1 more
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Nature, 2002
To understand complex biological systems requires the integration of experimental and computational research -- in other words a systems biology approach. Computational biology, through pragmatic modelling and theoretical exploration, provides a powerful foundation from which to address critical scientific questions head-on. The reviews in this Insight
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To understand complex biological systems requires the integration of experimental and computational research -- in other words a systems biology approach. Computational biology, through pragmatic modelling and theoretical exploration, provides a powerful foundation from which to address critical scientific questions head-on. The reviews in this Insight
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FEMS Yeast Research, 2008
Systems Biology (SB) is a rapidly developing field, which is expected to have a major impact on the future of biological and medical research. It aims at system-level understanding of biological processes employing mathematical analysis and computational tools to integrate the information content obtained in experimental biology.
Merja, Penttilä, Jens, Nielsen
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Systems Biology (SB) is a rapidly developing field, which is expected to have a major impact on the future of biological and medical research. It aims at system-level understanding of biological processes employing mathematical analysis and computational tools to integrate the information content obtained in experimental biology.
Merja, Penttilä, Jens, Nielsen
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Communications of the ACM, 2009
The convergence of CS and biology will serve both disciplines, providing each with greater power and relevance.
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The convergence of CS and biology will serve both disciplines, providing each with greater power and relevance.
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Membrane systems in systems biology
2008 9th International Workshop on Discrete Event Systems, 2008Membrane systems were introduced by Gh. Paun in 1998 as a class of distributed parallel computing devices of biochemical type, inspired from the functioning of living cells. Since then, they have been the subject of various studies, aimed at investigating and point out many aspects related to their computational power and efficiency. More recently, the
BESOZZI, DANIELA +3 more
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Introduction to systems biology
2007The developments in the molecular biosciences have made possible a shift to combined molecular and system-level approaches to biological research under the name of Systems Biology. It integrates many types of molecular knowledge, which can best be achieved by the synergistic use of models and experimental data.
Bruggeman, F.J. +3 more
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Metabolomics in Systems Biology
Annual Review of Plant Biology, 2003The primary aim of “omic” technologies is the nontargeted identification of all gene products (transcripts, proteins, and metabolites) present in a specific biological sample. By their nature, these technologies reveal unexpected properties of biological systems.
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