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Introduction to systems biology
2007The developments in the molecular biosciences have made possible a shift to combined molecular and system-level approaches to biological research under the name of Systems Biology. It integrates many types of molecular knowledge, which can best be achieved by the synergistic use of models and experimental data.
Bruggeman, F.J. +3 more
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Membrane systems in systems biology
2008 9th International Workshop on Discrete Event Systems, 2008Membrane systems were introduced by Gh. Paun in 1998 as a class of distributed parallel computing devices of biochemical type, inspired from the functioning of living cells. Since then, they have been the subject of various studies, aimed at investigating and point out many aspects related to their computational power and efficiency. More recently, the
BESOZZI, DANIELA +3 more
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Systems biology of the mitochondrion
American Journal of Physiology-Cell Physiology, 2006The promise of the current era of biological research is to understand the integrated function of biological systems in order to predict and rationally manipulate their behavior, with the ultimate aim of improving human health.
Daniel A, Beard, Marko, Vendelin
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Metabolomics in Systems Biology
Annual Review of Plant Biology, 2003The primary aim of “omic” technologies is the nontargeted identification of all gene products (transcripts, proteins, and metabolites) present in a specific biological sample. By their nature, these technologies reveal unexpected properties of biological systems.
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Systems biology of tuberculosis
Tuberculosis, 2011Systems biology seeks to study biological systems as a whole, by adopting an integrated approach to study and understand the function of biological systems, particularly, the response of such systems to various perturbations. In this article, we focus on the Indian efforts towards systems-level studies of Mycobacterium tuberculosis and its interaction ...
Chandra, Nagasuma +2 more
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2010
Cancer is a complex and heterogeneous disease, not only at a genetic and biochemical level, but also at a tissue, organism, and population level. Multiple data streams, from reductionist biochemistry in vitro to high-throughput "-omics" from clinical material, have been generated with the hope that they encode useful information about phenotype and ...
Dana, Faratian +4 more
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Cancer is a complex and heterogeneous disease, not only at a genetic and biochemical level, but also at a tissue, organism, and population level. Multiple data streams, from reductionist biochemistry in vitro to high-throughput "-omics" from clinical material, have been generated with the hope that they encode useful information about phenotype and ...
Dana, Faratian +4 more
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Current Opinion in Structural Biology, 2007
Oil and water do not normally mix, and apparently structural biology and systems biology look like two different universes. It can be argued that structural biology could play a very important role in systems biology. Although at the final stage of understanding a signal transduction pathway, a cell, an organ or a living system, structures could be ...
Beltrao, Pedro +2 more
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Oil and water do not normally mix, and apparently structural biology and systems biology look like two different universes. It can be argued that structural biology could play a very important role in systems biology. Although at the final stage of understanding a signal transduction pathway, a cell, an organ or a living system, structures could be ...
Beltrao, Pedro +2 more
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The Systems Biology of Glycosylation
ChemInform, 2004AbstractFor Abstract see ChemInform Abstract in Full Text.
Michael P, Murrell +2 more
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2018
The aim of this volume is to encourage the use of systems-level methodologies to contribute to the improvement of human-health . We intend to motivate biomedical researchers to complement their current theoretical and empirical practice with up-to-date systems biology conceptual approaches.
María Elena, Álvarez-Buylla Roces +4 more
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The aim of this volume is to encourage the use of systems-level methodologies to contribute to the improvement of human-health . We intend to motivate biomedical researchers to complement their current theoretical and empirical practice with up-to-date systems biology conceptual approaches.
María Elena, Álvarez-Buylla Roces +4 more
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The Language of Systems Biology
2014Systems Biology is an interdisciplinary approach to understand biological processes that act on different scales. For example biochemical pathways steer internal cell dynamics, which can lead to cell movement. Cell movement can lead to cancer invasion and cancer invasion can lead to a disease that affects the whole body. To understand such a process, a
DELITALA, MARCELLO EDOARDO, T. Hillen
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