Results 131 to 140 of about 1,058,962 (296)

Application of systems engineering to complex systems and system of systems

, 2017
Rick Sturdivant, Chong, Edwin K. P., Sega, Ronald M., Jayasumana, Anura P., Atadero, Rebecca   +4 more
openalex   +2 more sources

Commentary: Engineering an optimal mechanical circulatory support system for the cavopulmonary connection [PDF]

, 2019
Osami Honjo, Matthew G. Doyle, Cristina H. Amon   +2 more
openalex   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Sandia National Laboratories Hydrogen System Engineering (Power Parks) Quarterly Report.

, 2020
Andrew E. Lutz
openalex   +1 more source

Equation-free and variable free modeling for complex/multiscale systems. Coarse-grained computation in science and engineering using fine-grained models

, 2017
Ioannis G. Kevrekidis
openalex   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Process Systems Engineering in Precision Medicine: Opportunities in Autologous CAR-T Therapy. [PDF]

Eng Life Sci
Wayne Bequette B.
europepmc   +1 more source

Sensor-Driven Human-Robot Synergy: A Systems Engineering Approach. [PDF]

Sensors (Basel), 2022
Tsolakis N, Gasteratos A.
europepmc   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Symmetry Breaking in Chemical Systems: Engineering Complexity Through Self-Organization and Marangoni Flows. [PDF]

Adv Sci (Weinh)
Gore S, Paudyal BR, Rocha D, Ali M, Masmoudi N, Bae AJ, Diddens C, Lohse D, Steinbock O, Gholami A.   +9 more
europepmc   +1 more source