Results 151 to 160 of about 25,134,561 (338)

Application Quality Function Deployment (Qfd) Tool In Design Of Aero Pumps Based On System Engineering

, 2016
Zohre Soleymani, Meisam Amirzadeh
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Characterizing barriers to antibiotic stewardship for skin and soft-tissue infections in the emergency department using a systems engineering framework. [PDF]

Antimicrob Steward Healthc Epidemiol, 2022
Pulia MS, Schwei RJ, Hesse SP, Werner NE.   +3 more
europepmc   +1 more source

PLS-based hellinger distance method for fault detection in chemical engineering systems

K. Ramakrishna Kini, Fouzi Harrou, Muddu Madakyaru, Ying Sun, Mukund Kumar Menon   +4 more
openalex   +1 more source

A systems engineering approach to financial risk quantification in primary raw materials production

, 2015
Indranil Pan
openalex   +2 more sources

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Role of systems engineering attributes in enhancing supply chain resilience: Healthcare in context of COVID-19 pandemic. [PDF]

Heliyon, 2022
Hossain NUI, Fazio SA, Lawrence JM, Santibanez Gonzalez ED, Jaradat R, Alvarado MS.   +5 more
europepmc   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

The complexity of safety: Embracing systems engineering in radiation oncology. [PDF]

J Appl Clin Med Phys
Wong LM, Pawlicki T.
europepmc   +1 more source

WIP Complex Engineering Systems and Systems Engineering [PDF]

2018 IEEE 23rd International Conference on Emerging Technologies and Factory Automation (ETFA), 2018
openaire   +1 more source