Results 181 to 190 of about 25,134,561 (338)

Data Challenges in AI Systems and their Solutions: A Requirements and AI Engineering Systematic Literature Review and Comparison [PDF]

Yi Peng, Hans-Martin Heyn, Jennifer Horkoff   +2 more
openalex   +1 more source

An overview of process systems engineering approaches for process intensification: State of the art

Chemical Engineering and Processing, 2018
Yuhe Tian, S. Demirel, M. Hasan, E. Pistikopoulos   +3 more
semanticscholar   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Phage-based delivery systems: engineering, applications, and challenges in nanomedicines. [PDF]

J Nanobiotechnology
Wang H, Yang Y, Xu Y, Chen Y, Zhang W, Liu T, Chen G, Wang K.   +7 more
europepmc   +1 more source

A Cognitive Systems Engineering Approach Using Unsupervised Fuzzy C-Means Technique, Exploratory Factor Analysis and Network Analysis-A Preliminary Statistical Investigation of the Bean Counter Profiling Scale Robustness. [PDF]

Int J Environ Res Public Health, 2022
Rad D, Cuc LD, Lile R, Balas VE, Barna C, Pantea MF, Bâtcă-Dumitru GC, Szentesi SG, Rad G.   +8 more
europepmc   +1 more source

Model Driven Engineering for Designing Adaptive Multi-Agents Systems

, 2008
Sylvain Rougemaille, Frédéric Migeon, Christine Maurel, Marie-Pierre Gleizes   +3 more
openalex   +2 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Retraction Note: Systems engineering of Escherichia coli for high-level glutarate production from glucose. [PDF]

Nat Commun
Zhang Z, Chu R, Wei W, Song W, Ye C, Chen X, Wu J, Liu L, Gao C.   +8 more
europepmc   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

How Do Molecular Systems Engineering Scientists Frame the Ethics of Their Research? [PDF]

AJOB Empir Bioeth
da Silva RGL, Blasimme A, Vayena E, Ormond KE.   +3 more
europepmc   +1 more source