Results 181 to 190 of about 4,929,681 (330)

Engineering Contextual Information for Pervasive Multiagent Systems

, 2008
Gabriella Castelli, Marco Mamei, Franco Zambonelli   +2 more
openalex   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Entangled Autopoiesis: Reframing Psychotherapy and Neuroscience Through Cognitive Science and Systems Engineering. [PDF]

Brain Sci
Rad D, Maier M, Triff Z, Marcu R.
europepmc   +1 more source

Systems engineering analysis of diagnostic referral closed-loop processes. [PDF]

BMJ Open Qual, 2021
Nehls N, Yap TS, Salant T, Aronson M, Schiff G, Olbricht S, Reddy S, Sternberg SB, Anderson TS, Phillips RS, Benneyan JC.   +10 more
europepmc   +1 more source

Engineering a multi-sensor surveillance system with secure alerting for next-generation threat detection and response

Mohammad Naim Uddin, Hussain Nyeem
openalex   +1 more source

EUNOMIA (ΕΥΝΟΜIΑ): A REQUIREMENT ENGINEERING BASED COMPLIANCE FRAMEWORK FOR SOFTWARE SYSTEMS [PDF]

, 2018
PRISCILA ENGIEL
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Characterizing barriers to antibiotic stewardship for skin and soft-tissue infections in the emergency department using a systems engineering framework. [PDF]

Antimicrob Steward Healthc Epidemiol, 2022
Pulia MS, Schwei RJ, Hesse SP, Werner NE.   +3 more
europepmc   +1 more source

WIP Complex Engineering Systems and Systems Engineering [PDF]

2018 IEEE 23rd International Conference on Emerging Technologies and Factory Automation (ETFA), 2018
openaire   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source