Results 181 to 190 of about 4,736,102 (330)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Regulatory Components for Bacterial Cell-Free Systems Engineering. [PDF]

ACS Synth Biol
Lee PW, Maerkl SJ.
europepmc   +1 more source

Investigating the cognitive capacity constraints of an ICU care team using a systems engineering approach. [PDF]

BMC Anesthesiol, 2022
Park J, Zhong X, Dong Y, Barwise A, Pickering BW.   +4 more
europepmc   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Comparative Study of Machine Learning and System Identification for Process Systems Engineering Dynamics. [PDF]

Ind Eng Chem Res
Ahmed A, Del Rio-Chanona EA, Mercangöz M.   +2 more
europepmc   +1 more source

Turbulence health systems: engineering a rapidly adaptive health system for times of crisis. [PDF]

BMJ Health Care Inform, 2021
Coiera E, Braithwaite J.
europepmc   +1 more source

Systems Engineering Approaches to the Studies of Fishing Gear-II

, 1979
Teisuke MIURA
openalex   +2 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Engineering and cost comparison of three different all-dry cooling systems

, 1976
B.C. Fryer, David J. Braun, David J. Braun, D.W. Faletti, L.E. Wiles   +4 more
openalex   +2 more sources