Results 201 to 210 of about 4,929,681 (330)

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Comparative Study of Machine Learning and System Identification for Process Systems Engineering Dynamics. [PDF]

Ind Eng Chem Res
Ahmed A, Del Rio-Chanona EA, Mercangöz M.   +2 more
europepmc   +1 more source

Investigating the cognitive capacity constraints of an ICU care team using a systems engineering approach. [PDF]

BMC Anesthesiol, 2022
Park J, Zhong X, Dong Y, Barwise A, Pickering BW.   +4 more
europepmc   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Turbulence health systems: engineering a rapidly adaptive health system for times of crisis. [PDF]

BMJ Health Care Inform, 2021
Coiera E, Braithwaite J.
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

CONSTRUCTION OF THE SUPPORT SYSTEM FOR ILLEGAL ABANDONMENT AND UNSUITABLE PROCESSING PREVENT OF WASTE, AND ITS EMPIRICAL STUDY(Environmental Engineering)

, 2006
Hirotoshi Yoda
openalex   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

A systems engineering approach to alarm management on pediatric medical-surgical units. [PDF]

J Hosp Med
Ruppel H, Luo B, Rasooly IR, McNamara M, McLoone M, Kern-Goldberger A, Ferro DF, Albanowski K, Brent C, Cieplinski JA, Irizarry J, Rottenberg S, Hehir D, Stinson HR, Makeneni S, Hamershock RA, Won J, Bonafide CP.   +17 more
europepmc   +1 more source

Engineering and Physics Optimization of Breed and Burn Fast Reactor Systems; NUCLEAR ENERGY RESEARCH INITIATIVE (NERI) QUARTERLY PROGRESS REPORT

, 2005
Error, Pavel Hejzlar, Peter Yarsky, Mike Driscoll, Daniel M. Wachs, Kevan Weaver, Ken Czerwinski, Mike Pope, James R. Parry, Cliff Davis, Dustin Crawford, Thomas Hartmann, Pradip Saha   +12 more
openalex   +2 more sources