Results 201 to 210 of about 4,654,755 (329)

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

New horizons in systems engineering and thinking to improve health and social care for older people. [PDF]

Age Ageing
Aujla N, Tooman T, Arakelyan S, Kerby T, Hartley L, O'Donnell A, Guthrie B, Underwood I, Jacko JA, Anand A.   +9 more
europepmc   +1 more source

A Cognitive Systems Engineering Approach Using Unsupervised Fuzzy C-Means Technique, Exploratory Factor Analysis and Network Analysis-A Preliminary Statistical Investigation of the Bean Counter Profiling Scale Robustness. [PDF]

Int J Environ Res Public Health, 2022
Rad D, Cuc LD, Lile R, Balas VE, Barna C, Pantea MF, Bâtcă-Dumitru GC, Szentesi SG, Rad G.   +8 more
europepmc   +1 more source

Interactive graphics analysis system for nuclear engineering applications

, 1973
Michael Danchak, W.R. Moyer, M. Becker
openalex   +2 more sources

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

Molecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo, Yoshihiro Mezawa, Zixu Wang, Ahmet Acar, Yasuhiko Ito, Atsushi Takano, Yohei Miyagi, Tomoyuki Yokose, Toshinari Yamashita, Yataro Daigo, Takuya Shirakihara, Akira Orimo   +11 more
wiley   +1 more source

Phage-based delivery systems: engineering, applications, and challenges in nanomedicines. [PDF]

J Nanobiotechnology
Wang H, Yang Y, Xu Y, Chen Y, Zhang W, Liu T, Chen G, Wang K.   +7 more
europepmc   +1 more source

Using Health Systems Engineering Approaches to Prepare for Tailoring of Implementation Interventions. [PDF]

J Gen Intern Med, 2021
Barnes GD, Acosta J, Kurlander JE, Sales AE.   +3 more
europepmc   +1 more source

Base line data [PDF]

, 1975
Georgia Institute of Technology(School of Industrial and Systems Engineering)
core  

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

Retraction Note: Systems engineering of Escherichia coli for high-level glutarate production from glucose. [PDF]

Nat Commun
Zhang Z, Chu R, Wei W, Song W, Ye C, Chen X, Wu J, Liu L, Gao C.   +8 more
europepmc   +1 more source