Results 241 to 250 of about 4,929,681 (330)

Adaptive Content Tuning of Social Network Digital Health Interventions Using Control Systems Engineering for Precision Public Health: Cluster Randomized Controlled Trial.

J Med Internet Res, 2023
Rocha P, Pinheiro D, de Paula Monteiro R, Tubert E, Romero E, Bastos-Filho C, Nuno M, Cadeiras M.   +7 more
europepmc   +1 more source

A systems biology pipeline identifies regulatory networks for stem cell engineering

, 2019
Melissa A. Kinney, Linda T. Vo, Jenna M. Frame, Jessica Barragan, Ashlee J. Conway, Shuai Li, Kwok‐Kin Wong, James J. Collins, Patrick Cahan, Trista E. North, Douglas A. Lauffenburger, George Q. Daley   +11 more
openalex   +2 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Environmental cleaning and disinfection in the operating room: a systematic scoping review through a human factors and systems engineering lens. [PDF]

Infect Control Hosp Epidemiol
Xie A, Sax H, Daodu O, Alam L, Sultan M, Rock C, Stewart CM, Perry SJ, Gurses AP.   +8 more
europepmc   +1 more source

Wireless sensors network based physiological parameters monitoring system : a project report [i.e. thesis] submitted in partial fulfilment of the requirements for the degree of Master of Engineering in Electronics and Telecommunication Engineering, School of Engineering and Advanced Technology, Massey University, Palmerston North, New Zealand

, 2010
Karandeep Malhi
openalex   +1 more source

Intelligence based Defense System to Protect from Advanced Persistent Threat by means of Social Engineering on Social Cloud Platform

, 2015
J. Vijaya Chandra, Narasimham Challa, Sai Kiran Pasupuleti   +2 more
openalex   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

From lab to society: Fostering clinical translation of molecular systems engineering. [PDF]

Bioeng Transl Med
da Silva RGL, Blasimme A.
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source