Results 91 to 100 of about 33,318,051 (318)

Dynamic Congested Traffic States of Density Difference Lattice Hydrodynamic Model with On-Ramp

open access: yesDiscrete Dynamics in Nature and Society, 2013
The density difference lattice hydrodynamic model with on-ramp is proposed. Stochastic and deterministic rules for the on-ramp flow entering into the main road are designed. Under the stochastic rule, various empirical spatiotemporal patterns can be well
Jun-fang Tian   +3 more
doaj   +1 more source

Theory of reliable systems [PDF]

open access: yes
An attempt was made to refine the current notion of system reliability by identifying and investigating attributes of a system which are important to reliability considerations.
Meyer, J. F.
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Timetable Design for Urban Rail Line with Capacity Constraints

open access: yesDiscrete Dynamics in Nature and Society, 2015
To design an efficient and economical timetable for a heavily congested urban rail corridor, a scheduling model is proposed in this paper. The objective of the proposed model is to find the departure time of trains at the start terminal to minimize the ...
Yu-Ting Zhu   +3 more
doaj   +1 more source

Mode 3 knowledge production: systems and systems theory, clusters and networks

open access: yes, 2016
With the comprehensive term of “Mode 3,” we want to draw a conceptual link between systems and systems theory and want to demonstrate further how this can be applied to knowledge in the next steps. Systems can be understood as being composed of “elements”
E. Carayannis, D. J. Campbell, S. Rehman
semanticscholar   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Large-Scale Demand Driven Design of a Customized Bus Network: A Methodological Framework and Beijing Case Study

open access: yesJournal of Advanced Transportation, 2017
In recent years, an innovative public transportation (PT) mode known as the customized bus (CB) has been proposed and implemented in many cities in China to efficiently and effectively shift private car users to PT to alleviate traffic congestion and ...
Jihui Ma   +6 more
doaj   +1 more source

Driving-Simulator-Based Test on the Effectiveness of Auditory Red-Light Running Vehicle Warning System Based on Time-To-Collision Sensor

open access: yesSensors, 2014
The collision avoidance warning system is an emerging technology designed to assist drivers in avoiding red-light running (RLR) collisions at intersections.
Xuedong Yan   +3 more
doaj   +1 more source

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